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BROMOPRIDE

BROMOPRIDE structure

CAS No.: 4093-35-0

Chemical Name:: BROMOPRIDE

Synonyms: Emoril;Viadil;Artomey;Praiden;Plesium;Opridan;Emepride;val13081;BROMOPRID;VAL 13081

CBNumber:: CB8288660

Molecular Formula:: C14H22BrN3O2

Molecular Weight:: 344.25

MDL Number:: MFCD00078959

MOL File:: 4093-35-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

Product description	Number	Pack Size	Price
Bromopride ≥95%	29329	1mg	$36
Bromopride ≥95%	29329	5mg	$145
Bromopride ≥95%	29329	10mg	$236
Bromopride ≥95%	29329	25mg	$502
Bromopride	TRC-B686645-5MG	5mg	$107
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BROMOPRIDE Properties

Melting point	148-150C
Boiling point	435.8±45.0 °C(Predicted)
Density	1.4132 (rough estimate)
refractive index	1.6200 (estimate)
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	13.84±0.46(Predicted)
color	White to Off-White
InChI	InChI=1S/C14H22BrN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)
InChIKey	GIYAQDDTCWHPPL-UHFFFAOYSA-N
SMILES	C(NCCN(CC)CC)(=O)C1=CC(Br)=C(N)C=C1OC
FDA UNII	75473V2YZK
ATC code	A03FA04

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H312-H332

Precautionary statements

P280

Hazard Codes

Risk Statements

20/21/22

Safety Statements

WGK Germany

RTECS

BZ3280000

NFPA 704

	0
3		0

BROMOPRIDE price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	29329	Bromopride ≥95%	4093-35-0	1mg	$36	2026-04-30	Buy
Cayman Chemical	29329	Bromopride ≥95%	4093-35-0	5mg	$145	2026-04-30	Buy
Cayman Chemical	29329	Bromopride ≥95%	4093-35-0	10mg	$236	2026-04-30	Buy
Cayman Chemical	29329	Bromopride ≥95%	4093-35-0	25mg	$502	2026-04-30	Buy
TRC	TRC-B686645-5MG	Bromopride	4093-35-0	5mg	$107	2026-06-03	Buy

Product number	Packaging	Price	Buy
29329	1mg	$36	Buy
29329	5mg	$145	Buy
29329	10mg	$236	Buy
29329	25mg	$502	Buy
TRC-B686645-5MG	5mg	$107	Buy

BROMOPRIDE Chemical Properties,Uses,Production

Description

Bromopride is a dopamine D₂ receptor antagonist (K_i = 14 nM). It binds to bovine anterior pituitary membranes with an IC₅₀ value of 2.13 μM. Bromopride inhibits cholinesterase activity in vitro in rat plasma and striatum homogenate (IC₅₀s = 67.8 and 38.4 μM, respectively). It increases serum prolactin levels in rats by 100% when used at a dose of 0.02 mol/kg. Bromopride (2.5 mg/kg) decreases locomotion and rearing in an open field test and impairs acquistion, but not retention, of a conditioned avoidance response in a two-way active conditioned avoidance test in rats.

Chemical Properties

White Solid

Originator

Praiden,Italchemi,Italy,1977

Uses

An antiemetic.Bromopride is used in method and a system for analyzing neuropharmacology of a drug.

Definition

ChEBI: 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide is a member of benzamides.

Manufacturing Process

To 119 g (0.45 mol) of N-(2-diethylaminoethyl)-2-methoxy-4-aminobenzamide dissolved in 200 cc of acetic acid are added in the cold in small portions 69 g of acetic anhydride (0.45 mol + 50% excess). The starting material is made by esterifying 4-aminosalicylic acid with methanol, then acetylating with acetic anhydride and then methylating with dimethyl sulfate. The solution obtained is heated for 2 hours on a water bath and then boiled for 15 minutes. It is cooled at 25°C. While agitating constantly and maintaining the temperature between 25° and 30°C, there is added to the solution drop by drop 72 g of bromine dissolved in 60 cc of acetic acid. It is agitated for one hour. The mixture obtained is added to one liter of water and the base is precipitated by the addition of 30% soda, The precipitated base is extracted with 40 cc of methylene chloride. After evaporation of the solvent, the residue is boiled for two hours with 390 g of concentrated hydrochloric acid in 780 cc of water. It is cooled, diluted with one liter of water, 12 g of charcoal are added, and the mixture filtered. The base is precipitated with 30% soda. The N-(2- diethylaminoethyl)-2-methoxy-4-amino-5-bromobenzamide formed crystallizes, is centrifuged and washed with water. A yield of 85 g of base having a melting point of 129°-130°C is obtained.
To produce the dihydrochloride, the free base is dissolved in 110 cc of absolute alcohol, 9.6 g of dry hydrochloric acid dissolved in 35 cc of alcohol are added, followed by 2.8 cc of water. The dihydrochloride precipitates, is centrifuged, washed, and dried at 40°C. It was a solid white material having a melting point of 134°-135°C.

Therapeutic Function

Antiemetic

References

[1] M. TONINI. Clinical implications of enteric and central D2 receptor blockade by antidopaminergic gastrointestinal prokinetics[J]. Alimentary Pharmacology & Therapeutics, 2004, 19 4: 379-390. DOI: 10.1111/j.1365-2036.2004.01867.x
[2] HERBERT Y. MELTZER Rebecca S Miljana Simonovic. Effects of a series of substituted benzamides on rat prolactin secretion and 3H-spiperone binding to bovine anterior pituitary membranes[J]. Life sciences, 1983, 32 25: Pages 2877-2886. DOI: 10.1016/0024-3205(83)90324-7
[3] A G NASELLO. Differential effects of bromopride and domperidone on cholinesterase activity in rat tissues.[J]. Life sciences, 1995, 56 3: 151-156. DOI: 10.1016/0024-3205(94)00429-v
[4] ANTONIA GLADYS NASELLO Luciano F F Maria Luzinete Alves Vanzeler. A Comparison of Bromopride and Domperidone Effects on Rat Conditioned Avoidance and Motor Activity[J]. Basic & Clinical Pharmacology & Toxicology, 1991, 68 1: 46-50. DOI: 10.1111/j.1600-0773.1991.tb01206.x

BROMOPRIDE Preparation Products And Raw materials

Raw materials

Dimethyl sulfate 4-Aminosalicylic acid Methanol Acetic anhydride

Preparation Products

BROMOPRIDE Suppliers

Global( 121)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Xiamen AmoyChem Co., Ltd	+86-86-5926051114	sales@amoychem.com	China	6339	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58
AFINE CHEMICALS LIMITED	+86-571-85134551 +86-18958018566	info@afinechem.com	China	15050	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Alfa Chemistry	+1-5166625404;	Info@alfa-chemistry.com	United States	20000	58
Shaanxi Didu New Materials Co. Ltd	+86-86-17392712779 +86-13289823923	1090@dideu.com	China	8651	58

Supplier	Advantage
Xiamen AmoyChem Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
AFINE CHEMICALS LIMITED	58
BOC Sciences	58
Alfa Chemistry	58
Shaanxi Didu New Materials Co. Ltd	58

View Lastest Price from BROMOPRIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-16	Bromopride 4093-35-0	$56.00-179.00		99.95%	10g	TargetMol Chemicals Inc.
	2026-07-15	Bromopride 4093-35-0	$56.00-179.00		99.95%	10g	TargetMol Chemicals Inc.

Bromopride
4093-35-0
$56.00-179.00
99.95%
TargetMol Chemicals Inc.

Bromopride
4093-35-0
$56.00-179.00
99.95%
TargetMol Chemicals Inc.

BROMOPRIDE Spectrum

BROMOPRIDE(4093-35-0)¹HNMR

4093-35-0(BROMOPRIDE)Related Search:

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5-BROMOSALICYLAMIDE Saletamide 5-BROMO-2-METHOXYBENZYLAMINE 5-BROMO-2-HYDROXYBENZYLAMINE N-(5-BROMO-2-METHOXYBENZYL)-N-METHYLAMINE

2-BROMO-5-METHOXYANILINE HCL (3-BROMOBENZYL)METHYLAMINE 5-Bromo-2-chlorobenzoic acid procainamide 5-Bromosalicylaldehyde

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4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide,Emepride,Emoril,Viadil BROMOPRID 2-Methoxy-4-aMino-5-broMo-N,N-diethylaMinoethylbenzaMide Opridan Plesium Praiden 4-azanyl-5-bromo-N-(2-diethylaminoethyl)-2-methoxy-benzamide 4-amino-5-bromo-n-(2-(diethylamino)ethyl)-2-methoxy-benzamid 4-amino-5-bromo-n-(2-(diethylamino)ethyl)-o-anisamid 4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide Artomey Benzamide, 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxy- Bromoprida Emepride Emoril n-(diethylaminoethyl)-2-methoxy-4-amino-5-bromobenzamide o-Anisamide, 4-amino-5-bromo-N-[2-(diethylamino)ethyl]- VAL 13081 val13081 Valopride Viadil 4-AMINO-5-BROMO-N-[2-(DIETHYL-AMINO)ETHYL-O-ANISAMIDE BROMOPRIDE BromoprideQ: What is Bromopride Q: What is the CAS Number of Bromopride Q: What is the storage condition of Bromopride Q: What are the applications of Bromopride Inhibitor,Bromopride,Dopamine Receptor,inhibit Bromopride in methanol Bromopride, 10 mM in DMSO Bromothyroxine Bromopride Impurity 8 4093-35-0 C14H22BrN3O2 BI - BZ Alphabetic Analytical Chromatography Product Catalog Analytical Standards Intermediates & Fine Chemicals Pharmaceuticals Amines Aromatics EMEPRIDE