Vascular endothelial growth factor-related protein
- CAS No.
- Chemical Name:
- Vascular endothelial growth factor-related protein
- Synonyms
- VEGF-C;VRP;VEGFC;Flt4-L;TBC1D8;LMPH1D;Flt4 ligand;VEGF-C human;VEGF-C from rat;VEGF-C from mouse
- CBNumber:
- CB82895237
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03458368
- MOL File:
- Mol file
- TDS File:
- TDS
Vascular endothelial growth factor-related protein price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3184 | VEGF-C human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture | 20μg | $381 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SAB1303607 | ANTI-VEGFC (VEGF3) (CENTER M263) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400μL | $532 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SAB1303101 | ANTI-VEGFC antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400μl | $532 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SRP4633 | VEGF-C human recombinant, expressed in E. coli, ≥90% (SDS-PAGE) | 10μg | $356 | 2025-07-31 | Buy | |
| Sigma-Aldrich | SRP6020 | VEGF-C from rat recombinant, expressed in E. coli, ≥90% (SDS-PAGE) | 10μg | $342 | 2024-03-01 | Buy |
Vascular endothelial growth factor-related protein Chemical Properties, Uses, Production
Uses
VEGF-C human has been used to determine cell proliferation and survival.
Biological Activity
VEGF-C (vascular endothelial growth factor-C) promotes tumorigenesis, by inducing lymphatic metastasis. The production of VEGF-C is stimulated by pro-fibrotic transforming growth factor β. The main function of VEGF-C is to mediate lymphangiogenesis. Overexpression of VEGF-C in keratinocytes of skin causes dermal lymphatic vessel hyperplasia.
Description
VEGF-C Human Recombinant- contains 121 amino acids residues including 6 amino acid His-tag fused at the C-terminal end. As a result of glycosylation VEGF-C migrates as an 18-24 kDa protein in SDS-PAGE under reducing conditions.
Source
Sf9, Insect Cells
Background
VEGF-C, also known as Vascular Endothelial Growth Factor Related Protein (VRP), is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. Human VEGF-C cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant human VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT-4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. Although recombinant human VEGF-C is also a mitogen for vascular endothelial cells, it is much less potent than VEGF-A.
Vascular endothelial growth factor-related protein Preparation Products And Raw materials
Raw materials
Preparation Products
Vascular endothelial growth factor-related protein Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9925 | 58 |
| Shanghai Yingxin Laboratory Equipment Co., Ltd. | 021-59178156 17002132182 | 3146474380@qq.com | China | 9997 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| ACROBiosystems | 13121935750 | jiaxin.zhao@acrobiosystems.com | China | 1582 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8165 | 58 |
| shlmai | 021-67680335 13052188602 | sale1@shlmai.net | China | 10000 | 58 |
