2-Iodo-6-nitrotoluene
- CAS No.
- 41252-98-6
- Chemical Name:
- 2-Iodo-6-nitrotoluene
- Synonyms
- 2-Iodo-6-nitrotoluene;2-Iodo-6-nitrotoluene, 95%;3-Iodo-2-methyl nitro benzene;5-IODO-6-METHYL-1-NITROBENZENE;Benzene, 1-iodo-2-methyl-3-nitro-
- CBNumber:
- CB8289748
- Molecular Formula:
- C7H6INO2
- Molecular Weight:
- 263.03
- MDL Number:
- MFCD08272202
- MOL File:
- 41252-98-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H227 |
| Precautionary statements | P501-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235 |
2-Iodo-6-nitrotoluene price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | RBA25298 | 1-Iodo-2-methyl-3-nitrobenzene | 41252-98-6 | 0.25g | $250 | 2026-06-05 | Buy |
| Biosynth | RBA25298 | 1-Iodo-2-methyl-3-nitrobenzene | 41252-98-6 | 2.5g | $855.5 | 2026-06-05 | Buy |
| Activate Scientific | AS49713 | 1-Iodo-2-methyl-3-nitrobenzene 98% | 41252-98-6 | 1g | $31 | 2026-06-04 | Buy |
| Activate Scientific | AS49713 | 1-Iodo-2-methyl-3-nitrobenzene 98% | 41252-98-6 | 5g | $105 | 2026-06-04 | Buy |
| Activate Scientific | AS49713 | 1-Iodo-2-methyl-3-nitrobenzene 98% | 41252-98-6 | 25g | $325 | 2026-06-04 | Buy |
2-Iodo-6-nitrotoluene Chemical Properties,Uses,Production
Synthesis
603-83-8
41252-98-6
General procedure for the synthesis of 2-iodo-6-nitrotoluene from 2-methyl-3-nitroaniline: 4.1.10. Synthesis of 2-methyl-3-nitroiodobenzene (26) Concentrated sulfuric acid (8 mL) was added to a solution of 2-methyl-3-nitroaniline (25) (5.00 g, 32.9 mmol) in water (50 mL). The reaction mixture was cooled to 0 °C and a solution of sodium nitrite (2.49 g, 36.2 mmol) in water (5 mL) was added slowly and dropwise. After the dropwise addition, the reaction mixture was continued to be stirred for 1 hour. Subsequently, a solution of potassium iodide (8.18 g, 49.3 mmol) in water (20 mL) was added slowly dropwise and stirring was continued for 1 hour after completion of the dropwise addition. Upon completion of the reaction, the reaction mixture was extracted with dichloromethane (330 mL). The organic phases were combined, washed with saturated aqueous sodium thiosulfate (Na2S2O3), dried over anhydrous sodium sulfate (Na2SO4), and concentrated under reduced pressure to remove the solvent to give the crude product. The crude product was purified by column chromatography with ethyl acetate/petroleum ether (1:10) as eluent to afford the target product 2-iodo-6-nitrotoluene as a yellow solid (7.43 g, 85% yield); melting point 36-37 ° C.; infrared spectra (thin-film method, cm1 ): 3082, 1591, 1519, 1443, 1348, 1273, 1204, 1087, 1001, 860, 794, 735, 696; 1H NMR (400 MHz, CDCl3): δ 2.52 (3H, s, CH3), 6.96 (1H, t, J = 8.0 Hz, aromatic hydrogen, H5), 7.64 (1H, dd, J = 8.0, 1.2 Hz, aromatic hydrogen, H6), 7.80 (1H, dd, J = 8.0, 1.2 Hz, aromatic hydrogen, H6), 7.80 (1H, dd, J = 8.0, 1.2 Hz). J = 8.0, 1.2 Hz, aromatic hydrogen, H4); 13C NMR (100 MHz, CDCl3): δ 25.0 (CH3, ArCH3), 103.6 (quaternary, aromatic carbon, C1), 123.9 (aromatic hydrogen, C4), 128.0 (aromatic hydrogen, C5), 135.0 (quaternary, aromatic carbon, C2), 143.1 (aromatic hydrogen, C6), 150.4 (quaternary, aromatic carbon, C2), 143.1 (aromatic hydrogen, C2), 143.1 (aromatic hydrogen, C2), 150.1 (aromatic hydrogen, C2), 150.1 (aromatic hydrogen, C2), 150.1 (aromatic hydrogen, C2) C6), 150.4 (quaternary carbon, aromatic carbon, C3); mass spectrum (EI): m/z 262.9439; theoretical value of C7H6INO2 (M) 262.9443.
References
[1] Chemical & Pharmaceutical Bulletin, 1986, vol. 34, # 9, p. 3971 - 3973
[2] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 11, p. 3177 - 3180
[3] Chemical Communications, 2015, vol. 51, # 6, p. 1070 - 1073
[4] Tetrahedron, 2013, vol. 69, # 2, p. 758 - 769
[5] Patent: US2010/75952, 2010, A1. Location in patent: Page/Page column 89
2-Iodo-6-nitrotoluene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4975 | 55 |
| Yancheng KangdiSen Pharmaceutical Co., Ltd. | 13812573443;18052965989 | tongbenwan22@163.com | China | 1975 | 55 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 10000 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Sichuan BoYou Biotechnology Co., Ltd. | 028-65791793 18140026355 | 568470422@qq.com | China | 9961 | 58 |
| Henan Alfachem Co.,Ltd. | 0371-55051623 18137891487 | 3983243027@qq.com | China | 9965 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-58859352 17714375163 | qzhang@aikonchem.com | China | 15525 | 58 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10452 | 58 |
| Changzhou Yinghao Technology Development Co., Ltd | 15151934985 | sales@yingsapharm.com | China | 5457 | 58 |
View Lastest Price from 2-Iodo-6-nitrotoluene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | 2-IODO-6-NITROTOLUENE
41252-98-6
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
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- 2-IODO-6-NITROTOLUENE
41252-98-6
- $9.80
- ≥99%
- Career Henan Chemical Co
