8-Anilino-1-naphthalenesulfonic acid
- CAS No.
- 82-76-8
- Chemical Name:
- 8-Anilino-1-naphthalenesulfonic acid
- Synonyms
- ANS;PHENYL PERI ACID;1,8-ANS;ANSA;1-ANILINONAPHTHALENE-8-SULFONIC ACID;8-(Phenylamino)naphthalene-1-sulfonic acid;PHENYL ACID;ANSA/1,8-ANS;N-PHENYL PERI ACID;fluorescent probes
- CBNumber:
- CB8289935
- Molecular Formula:
- C16H13NO3S
- Molecular Weight:
- 299.34
- MDL Number:
- MFCD00003998
- MOL File:
- 82-76-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 8-Anilino-1-naphthalenesulfonic acid ≥97% (HPLC) | A1028 | 5g | $69.2 |
| 8-Anilino-1-naphthalenesulfonic acid ≥97% (HPLC) | A1028 | 25g | $191 |
| 8-Anilino-1-naphthalenesulfonic Acid >95.0%(HPLC)(T) | A0472 | 25g | $81 |
| 1,8-ANS ≥95% | 10010219 | 5g | $36 |
| 1,8-ANS ≥95% | 10010219 | 10g | $55 |
| More product size | |||
| Melting point | 215-217 °C (dec.)(lit.) |
|---|---|
| Density | 1.409±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMF: soluble50mg/mL |
| pka | 0.19±0.40(Predicted) |
| form | Powder |
| color | Dark green to brown to black |
| Appearance | Dark Grey to Black Solid |
| Merck | 13,664 |
| BRN | 1843887 |
| Major Application |
diagnostic assay manufacturing hematology histology |
| InChI | InChI=1S/C16H13NO3S/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13/h1-11,17H,(H,18,19,20) |
| InChIKey | FWEOQOXTVHGIFQ-UHFFFAOYSA-N |
| SMILES | C1(S(O)(=O)=O)=C2C(C=CC=C2NC2=CC=CC=C2)=CC=C1 |
| CAS DataBase Reference | 82-76-8(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | ANS |
| FDA UNII | 630I4V6051 |
| EPA Substance Registry System | 8-Anilino-1-naphthalenesulfonic acid (82-76-8) |
| UNSPSC Code | 12171500 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | - | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29214980 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
8-Anilino-1-naphthalenesulfonic acid price More Price(73)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A1028 | 8-Anilino-1-naphthalenesulfonic acid ≥97% (HPLC) | 82-76-8 | 5g | $69.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | A1028 | 8-Anilino-1-naphthalenesulfonic acid ≥97% (HPLC) | 82-76-8 | 25g | $191 | 2026-04-30 | Buy |
| TCI Chemical | A0472 | 8-Anilino-1-naphthalenesulfonic Acid >95.0%(HPLC)(T) | 82-76-8 | 25g | $81 | 2026-04-30 | Buy |
| Cayman Chemical | 10010219 | 1,8-ANS ≥95% | 82-76-8 | 5g | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 10010219 | 1,8-ANS ≥95% | 82-76-8 | 10g | $55 | 2026-04-30 | Buy |
8-Anilino-1-naphthalenesulfonic acid Chemical Properties,Uses,Production
Description
1,8-ANS is a fluorescent dye that binds with high affinity to hydrophobic surfaces of proteins. 1,8-ANS has an excitation maximum of 350 nm. It has an emission maximum of 520 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FABP2) it has emission maxima of 468-477 nm. 1,8-ANS binds to low polarity regions of protein surfaces making it well suited for determining the affinity of hydrophobic ligands to their corresponding binding proteins, such as the binding of free fatty acids to FABPs. 1,8-ANS binds to FABP2 with a Kd value of approximately 9.7 μM at 24.5°C.
Chemical Properties
green needles
Uses
Intermediate of dyestuff
Uses
8-Anilino-1-naphthalenesulfonic Acid is used as a fluorescent probe to identify hydrophobic sites. Dyes and metabolites.
Definition
CHEBI:8-anilinonaphthalene-1-sulfonic acid is a naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8. It has a role as a fluorescent probe. It is an aminonaphthalene and a naphthalenesulfonic acid.
Biotechnological Applications
8-Anilino-1-naphthalenesulfonic acid is a fluorescent dye with high affinity towards hydrophobic surfaces of proteins. It is useful for determining the affinity of hydrophobic ligands to their corresponding binding proteins. 8-Anilino-1-naphthalenesulfonic acid undergoes a blue shift and fluorescence increases when it binds to non-polar regions of a protein surface or membranes. Used as a probe to monitor protein-folding.
References
[1] ALEXANDER V PASTUKHOV Ira J R. Fluorescent dyes as probes to study lipid-binding proteins.[J]. Proteins-Structure Function and Bioinformatics, 2003, 53 3: 607-615. DOI: 10.1002/prot.10401
[2] W R KIRK F G P E Kurian. Characterization of the sources of protein-ligand affinity: 1-sulfonato-8-(1’)anilinonaphthalene binding to intestinal fatty acid binding protein.[J]. Biophysical journal, 1996, 70 1: 69-83. DOI: 10.1016/s0006-3495(96)79592-9
[3] J J ORY L J B. Studies of the ligand binding reaction of adipocyte lipid binding protein using the fluorescent probe 1, 8-anilinonaphthalene-8-sulfonate.[J]. Biophysical journal, 1999, 77 2: 1107-1116. DOI: 10.1016/s0006-3495(99)76961-4
Excitation / Emission Maximum
350 nm (free), 468 nm (bound)/520 nm (free), 477 nm (bound)
8-Anilino-1-naphthalenesulfonic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3379 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 | info@fortunachem.com | China | 5992 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14014 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | info@longyupharma.com | China | 2423 | 58 | |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
View Lastest Price from 8-Anilino-1-naphthalenesulfonic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-03 | 8-Anilino-1-naphthalenesulfonic acid
82-76-8
|
$10.00 | 1ASSAYS | 99% | 1 ton | RongNa Biotechnology Co.,Ltd | |
 |
2026-07-03 | 8-Anilino-1-naphthalenesulfonic acid
82-76-8
|
1KG | 98% | 50kgs/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-05-22 | 8-Anilino-1-naphthalenesulfonic acid
82-76-8
|
1G/KG | 99% | 10000000KG | Anhuyan (Hainan) Biotechnology Co., LTD |
-
- 8-Anilino-1-naphthalenesulfonic acid
82-76-8
- $10.00
- 99%
- RongNa Biotechnology Co.,Ltd
-
- 8-Anilino-1-naphthalenesulfonic acid
82-76-8
- 98%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 8-Anilino-1-naphthalenesulfonic acid
82-76-8
- $0.00
- 99%
- Anhuyan (Hainan) Biotechnology Co., LTD
