PHENACETIN-ETHOXY-1-13C
- CAS No.
- 72156-72-0
- Chemical Name:
- PHENACETIN-ETHOXY-1-13C
- Synonyms
- PHENACETIN-ETHOXY-1-13C;Phenacetin- oxethyl-1-13C;phenacetin-13c1(ethoxy-1-13c);ACETOPHENETIDIN (ETHOXY-1-13C);P-ACETOPHENETIDIDE-ETHOXY-1-13C;Phenacetin-ethoxy-1-13C;n-(4-ethoxy-1-13c-phenyl)acetamide;PHENACETIN-ETHOXY-1-13C, 98 ATOM % 13C;Acetamide, N-[4-(ethoxy-1-13C)phenyl]-;N-[4-ETHOXYPHENYL]ACETAMIDE (ETHOXY-1-13C)
- CBNumber:
- CB8298744
- Molecular Formula:
- C10H13NO2
- Molecular Weight:
- 180.22
- MDL Number:
- MFCD00083951
- MOL File:
- 72156-72-0.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H350-H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Hazard Codes | T |
| Risk Statements | 45-46-20/21/22-22 |
| Safety Statements | 53-22-36/37/39-45 |
| WGK Germany | 3 |
PHENACETIN-ETHOXY-1-13C price More Price(1)
PHENACETIN-ETHOXY-1-13C Chemical Properties,Uses,Production
Uses
Phenacetin-13C is the 13C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Chandrasekharan NV, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13926-31. DOI:10.1073/pnas.162468699
[3] Xiao-Meng He, et al. Effects of long-term smoking on the activity and mRNA expression of CYP isozymes in rats. J Thorac Dis. 2015 Oct 7(10): 1725–1731. DOI:10.3978/j.issn.2072-1439.2015.10.07
[4] Na Gao, et al. Inhibition of Baicalin on Metabolism of Phenacetin, a Probe of CYP1A2, in Human Liver Microsomes and in Rats. PLoS One. 2014 9(2): e89752. DOI:10.1371/journal.pone.0089752
PHENACETIN-ETHOXY-1-13C Preparation Products And Raw materials
Raw materials
Preparation Products
PHENACETIN-ETHOXY-1-13C Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Ouhe Technology Co., Ltd | 010-010-82967028 13552068683 | 2355560935@qq.com | China | 10442 | 60 |
| Shanghai wechem chemical co., ltd | 18824865657 | 2684615189@qq.com | China | 423 | 58 |
| Shanghai Nature Biotechnology Co., Ltd | (86)21-80370399-802,808 | sales@naturesci.cn | China | 85 | 58 |
| Hangzhou Jinghao Biotechnology Co., LTD | 17513242016 | 1576861551@qq.com | China | 2815 | 58 |
| Qingdao Tenglong microwave technology co., LTD. | 0532-83818797 18561885118 | market@tlwb.com.cn | China | 3944 | 58 |
| Reer Technology (Shanghai) Co., LTD | 021-64400900 15800436310 | bessey@reertech.com | China | 4105 | 58 |
| Shanghai isotope chemical co.,ltd | 021-51600108 13062666369 | sales@isotopechem.com | China | 4297 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 15102117276 19921389125 | tech@zzbioco.com | China | 12064 | 58 |
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
| Aikon International Limited | 025-58859352 18651614124 | 2881516338@qq.com | China | 9199 | 58 |