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Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester

Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester Structure
Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester structure
CAS No.
477585-43-6
Chemical Name:
Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester
Synonyms
(2S, 2R)-GLY-4-PYRANOYL-OME;methyl aminotetrahydropyr...;methyl 2-amino-2-(oxan-4-yl)acetate;Methyl aMinotetrahydropyran-4-ylacetate;METHYL AMINO-(4-TETRAHYDROPYRANYL) ACETATE;METHYL AMINO(TETRAHYDRO-2H-PYRAN-4-YL)ACETATE;methyl 2-amino-2-tetrahydropyran-4-yl-acetate;Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester;2H-Pyran-4-acetic acid, a-aMinotetrahydro-, Methyl ester;2H-Pyran-4-acetic acid, α-aminotetrahydro-, methyl ester
CBNumber:
CB8303842
Molecular Formula:
C8H15NO3
Molecular Weight:
173.21
MDL Number:
MFCD03425227
MOL File:
477585-43-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:38
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Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester Properties

Boiling point 244.130±10.00 °C(Press: 760.00 Torr)(predicted)
Density 1.105±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. 2-8°C(protect from light)
pka 7.237±0.50(predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H302-H350-H411
Precautionary statements  P201-P202-P264-P270-P273-P280-P301+P312+P330-P308+P313-P391-P405-P501
Hazard Codes  Xn
Risk Statements  22

Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 260920 Amino-(tetrahydropyran-4-yl)acetic acid methyl ester hydrochloride Asreported 477585-43-6 50mg $343 2026-06-03 Buy
Usbiological 260920 Amino-(tetrahydropyran-4-yl)acetic acid methyl ester hydrochloride Asreported 477585-43-6 100mg $472 2026-06-03 Buy
Usbiological 260920 Amino-(tetrahydropyran-4-yl)acetic acid methyl ester hydrochloride Asreported 477585-43-6 250mg $581 2026-06-03 Buy
Usbiological 260920 Amino-(tetrahydropyran-4-yl)acetic acid methyl ester hydrochloride Asreported 477585-43-6 500mg $765 2026-06-03 Buy
Usbiological 260920 Amino-(tetrahydropyran-4-yl)acetic acid methyl ester hydrochloride Asreported 477585-43-6 1g $1020 2026-06-03 Buy
Product number Packaging Price Buy
260920 50mg $343 Buy
260920 100mg $472 Buy
260920 250mg $581 Buy
260920 500mg $765 Buy
260920 1g $1020 Buy

Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester Chemical Properties, Uses, Production

Synthesis

Methyl 2-(benzyloxycarbonylaMino)-2-(2H-pyran-4(3H,5H,6H)-ylidene)acetate

477584-90-0

AMINO-(TETRAHYDRO-PYRAN-4-YL)-ACETIC ACID METHYL ESTER

477585-43-6

The general procedure for the synthesis of methyl 2-amino-2-(tetrahydro-2H-pyran-4-yl)acetate from methyl 2-(benzyloxycarbonylamino)-2-(tetrahydro-2H-pyran-4-yl)acetate was as follows: a mixture of methyl N-Cbz-dehydropyranosylglycinate (5.2 g, 17 mmol), 5% Pd/C catalyst (500 mg), methanol (75 mL) and tetrahydrofuran ( A mixture of methanol (75 mL) and tetrahydrofuran (25 mL) was placed under hydrogen atmosphere for 24 hours. Upon completion of the reaction, the mixture was filtered through diatomaceous earth and the diatomaceous earth was washed with methanol. The filtrate was concentrated under reduced pressure to give methyl 2-amino-2-(tetrahydro-2H-pyran-4-yl)acetate in quantitative yield as a colorless oil, which can be used directly in the next step of the reaction.

References

[1] Patent: WO2006/69063, 2006, A1. Location in patent: Page/Page column 80
[2] Patent: WO2010/21934, 2010, A2. Location in patent: Page/Page column 40-41
[3] Patent: WO2007/106192, 2007, A2. Location in patent: Page/Page column 50
[4] Patent: WO2008/134679, 2008, A1. Location in patent: Page/Page column 74
[5] Patent: WO2013/131408, 2013, A1. Location in patent: Page/Page column 110; 111

Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester Preparation Products And Raw materials

Raw materials

Methyl 2-(benzyloxycarbonylaMino)-2-(2H-pyran-4(3H,5H,6H)-ylidene)acetate Tetrahydrofuran Hydrogen Methanol

Preparation Products

Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester Suppliers

Global Suppliers ( 56)
Supplier Tel Email Country ProdList Advantage
Shanghai Boc Chemical Co.,Ltd 021-34975603-808 18721111801 sales@bocpharma.com China 991 64
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Shanghai potentpharm CO.,Ltd 13524892556 sales-cn@potentpharm.com China 1011 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Shanghai ChriChem Co., Ltd. 021-54880687 China 510 55
Shanghai Hong-chuang Pharma Tech Co., Ltd. 18151128828 hc-sales@foxmail.com China 2635 55
Shanghai Carlow Chemicals Co., Ltd. 21-33526724 18930996265 info@carlowchem.com China 1996 58
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Tianjin Anhao Biological Technology Co., Ltd. sales@ahpharmatech.com China 5734 55
SPIRO PHARMA eric_feng1954@126.com China 9239 55
Supplier Advantage
Shanghai Boc Chemical Co.,Ltd 64
Hangzhou Sage Chemical Co., Ltd. 58
Shanghai potentpharm CO.,Ltd 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Shanghai ChriChem Co., Ltd. 55
Shanghai Hong-chuang Pharma Tech Co., Ltd. 55
Shanghai Carlow Chemicals Co., Ltd. 58
ShangHai AmK Pharmaceutical Technology Co., Ltd. 55
Tianjin Anhao Biological Technology Co., Ltd. 55
SPIRO PHARMA 55

Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester Spectrum

AMINO-(TETRAHYDRO-PYRAN-4-YL)-ACETIC ACID METHYL ESTER(477585-43-6)1HNMR

477585-43-6 (Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester) Related Search:

(4-Amino-tetrahydro-pyran-4-yl)-acetic acid methyl ester Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester HCl (S)-Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester (R)-Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester hydrochloride (R)-Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester
4-Amino-tetrahydropyran-4-acetic acid methyl ester HCl Amino-(tetrahydro-pyran-4-yl)-acetic acid Benzyloxycarbonylamino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester tert-Butoxycarbonylamino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester

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(2S, 2R)-GLY-4-PYRANOYL-OME METHYL AMINO(TETRAHYDRO-2H-PYRAN-4-YL)ACETATE METHYL AMINO-(4-TETRAHYDROPYRANYL) ACETATE methyl aminotetrahydropyr... Methyl aMinotetrahydropyran-4-ylacetate 2H-Pyran-4-acetic acid, a-aMinotetrahydro-, Methyl ester Methyl 2-aMino-2-(tetrahydro-2H-pyran-4-yl)acetate hydrochloride methyl 2-amino-2-(oxan-4-yl)acetate 2H-Pyran-4-acetic acid, α-aminotetrahydro-, methyl ester methyl 2-amino-2-tetrahydropyran-4-yl-acetate Amino-(tetrahydro-pyran-4-yl)-acetic acid methyl ester 477585-43-6