2-(Azido-PEG2-amido)-1,3-propandiol
- CAS No.
- 1398044-52-4
- Chemical Name:
- 2-(Azido-PEG2-amido)-1,3-propandiol
- Synonyms
- 2-(Azido-PEG2-amido)-1,3-propandiol
- CBNumber:
- CB83062270
- Molecular Formula:
- C10H20N4O5
- Molecular Weight:
- 276.29
- MDL Number:
- MFCD22574770
- MOL File:
- 1398044-52-4.mol
2-(Azido-PEG2-amido)-1,3-propandiol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114953 | 2-(Azido-PEG2-amido)-1,3-propandiol ≥98% | 1398044-52-4 | 1g | $1398 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1124 | 2-(Azido-PEG2-amido)-1,3-propandiol 97% | 1398044-52-4 | 250mg | $531 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1124 | 2-(Azido-PEG2-amido)-1,3-propandiol 97% | 1398044-52-4 | 500mg | $908 | 2026-06-04 | Buy |
| Apolloscientific | BIPG1124 | 2-(Azido-PEG2-amido)-1,3-propandiol 97% | 1398044-52-4 | 1g | $1510 | 2026-06-04 | Buy |
| BroadPharm | bp-20966 | 2-(Azido-PEG2-amido)-1,3-propandiol 97% | 1398044-52-4 | 250MG | $260 | 2026-05-24 | Buy |
2-(Azido-PEG2-amido)-1,3-propandiol Chemical Properties, Uses, Production
Description
2-(Azido-PEG2-amido)-1,3-propandiol is a branched PEG derivtive containing terminal azide moieties and two primary alcohol groups. The azide group can participate in copper-catalyzed Click Chemistry reactions with alkyne, DBCO and BCN moieties. The hydroxyl groups can react to further derivatize the compound. PEG linker increases solubility of compounds in aqueous media.
Uses
2-(Azido-PEG2-amido)-13-propandiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 2-(Azido-PEG2-amido)-1,3-propandiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
2-(Azido-PEG2-amido)-1,3-propandiol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Affinity（Wuhan）Ltd. | 15841022315 | sales@affinitytech.cn | China | 2980 | 58 |
| Shandong fen Boyu Biotechnology Co.,LTD | 13356310019 13356310019; | boyu2024@163.com | China | 3947 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38904 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
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