PROMETON
- CAS No.
- 1610-18-0
- Chemical Name:
- PROMETON
- Synonyms
- Prometone;G31435;Ontrack;PRAMITOL;PROMETON;Gesafram;Gesagram;Primatol O;NSC 163048;gesafram50
- CBNumber:
- CB8308519
- Molecular Formula:
- C10H19N5O
- Molecular Weight:
- 225.29
- MDL Number:
- MFCD00047343
- MOL File:
- 1610-18-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 118-121℃ |
|---|---|
| Boiling point | 366.8°C (rough estimate) |
| Density | 1.1038 (rough estimate) |
| refractive index | 1.7610 (estimate) |
| storage temp. | 0-6°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 4.36±0.41(Predicted) |
| form | Solid |
| color | White to Pale Beige |
| Water Solubility | 0.75g/L(21 ºC) |
| Merck | 13,7880 |
| Henry's Law Constant | 1.1×104 mol/(m3Pa) at 25℃, HSDB (2015) |
| EWG's Food Scores | 1 |
| FDA UNII | DY7SQ0399L |
| EPA Substance Registry System | Prometon (1610-18-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | UN2763 |
| RTECS | XY4200000 |
| TSCA | TSCA listed |
| HS Code | 29336990 |
| Hazardous Substances Data | 1610-18-0(Hazardous Substances Data) |
| Toxicity | LD50 in mice, rats (mg/kg): 2160, 2980 orally (Gysin, Knüsli, 1960); LC50 (96 hour) in bluegill sunfish, rainbow trout (ppm): >32, 20 (Tweedy, Kahrs) |
PROMETON price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P757035 | Prometon | 1610-18-0 | 25mg | $95 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 42082 | Prometon | 1610-18-0 | 25mg | $595 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0008979 | PROMETON 95.00% | 1610-18-0 | 10MG | $909.56 | 2021-12-16 | Buy |
PROMETON Chemical Properties,Uses,Production
Description
Prometon is a non-selective herbicide. It is moderately soluble in water, volatile and, based on its chemical properties, it is highly mobile and has a high potential to leach to groundwater. It can be highly persistent in both soil and aquatic systems. It has a relatively low mammalian toxicity and is not expected to bioaccumulate. It is classified as an irritant. It is moderately toxic to birds, most aquatic species and honeybees.
Chemical Properties
Colorless crystalline solid or white powder. Odorless.
Uses
Nonselective herbicide.
Uses
Nonselective preemergence and postemergence herbicide used to control most annual and perennial broad-leaved weeds, grasses and brush weeds on noncrop land.
Production Methods
The industrial synthesis of prometon begins with the formation of the 1,3,5-triazine ring, typically derived from cyanuric chloride or melamine. The triazine core undergoes sequential nucleophilic substitution with isopropylamine to introduce the two diisopropylamino groups at the 2- and 4-positions. The final step involves methoxylation at the 6-position using sodium methoxide or methanol under basic conditions. These reactions are carried out in organic solvents such as acetone or acetonitrile under controlled temperature and pH to ensure high yield and selectivity. After synthesis, the crude product is purified through crystallisation or solvent extraction.
Definition
ChEBI: A methoxy-1,3,5-triazine that is 6-methoxy-1,3,5-triazine-2,4-diamine in which the one of the hydrogens of each amino group is substituted by an isopropyl group.
Hazard
Toxic by ingestion.
Agricultural Uses
Herbicide: A non-selective pre-emergence and post-emergence herbicide. Use around buildings, storage areas, industrial sites, fences, recreational areas, rights-of-way, railroads, pipelines, lumberyards, tank farms, and similar areas. Controls broadleaf weeds and grasses over an extended period of time. Not listed for use in EU countries. Registered for use in the U.S.
Trade name
ACME® Prometon; G-31435®; GESAFRAM® 50; GESAFRAM®; GESAGRAM®; GROUND ZERO®; KLEENWALK®; NIX®; NOXALL®; ONTRACK®; PRIMATOL® (prometon); PROMETONE®; WEED-GO®
Mechanism of action
Non-selective, systemic absorbed by foliage and roots, inhibits photosynthesis. Affects photosystem II competing with plastoquinone and modifying electron transport processes.
Potential Exposure
A nonselective pre-emergence and postemergence triazine herbicide. Use around buildings, storage areas, industrial sites, fences, recreational areas, rights-of-way, railroads, pipelines, lumberyards, tank farms, and similar areas. Controls broadleaf weeds and grasses over an extended period of time
Environmental Fate
Soil. Degrades in soil yielding hydroxy metabolites and dealkylation of the side chains
(Hartley and Kidd, 1987).
Photolytic. Pelizzetti et al. (1990) studied the aqueous photocatalytic degradation of
prometon and other s-triazines (ppb level) using simulated sunlight (λ >340 nm) and
titanium dioxide as a photocatalyst. Prometon rapidly degraded forming cyanuric acid,
nitrates, the intermediate tentatively identified as 2,4-diamino-6-hydroxy-N,N′-bis(1-methylethyl)-1,3,5-triazine and other intermediate compounds similar to those found for atrazine. Mineralization of cyanuric acid to carbon dioxide was not observed (Pelizzetti et al.,
1990).
Shipping
UN2763 Triazine pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explo- sions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. UV causes decomposition.
Waste Disposal
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed. In accordance with 40CFR165, follow recom- mendations for the disposal of pesticides and pesticide containers. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
Pesticide Type
Herbicide
PROMETON Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29988 | 65 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9656 | 58 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
| TianJin Alta Scientific Co., Ltd. | 022-65378550-8551 | contact@altascientific.com | China | 2772 | 58 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
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