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CeMMEC1

CeMMEC1 Structure
CeMMEC1 structure
CAS No.
440662-09-9
Chemical Name:
CeMMEC1
Synonyms
cemmecl;CeMMEC1;CeMMEC1(free base);CeMMEC1 (CeMMEC 1);CeMMEC1, 10 mM in DMSO;Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide;4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-;N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
CBNumber:
CB83171705
Molecular Formula:
C19H16N2O4
Molecular Weight:
336.34
MDL Number:
MFCD02939849
MOL File:
440662-09-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-20 23:19:27
Product description Number Pack Size Price
CeMMEC1 ≥98% 19956 500μg $36
CeMMEC1 ≥98% 19956 1mg $68
CeMMEC1 ≥98% 19956 5mg $268
CeMMEC1 ≥98% 19956 10mg $469
CeMMEC1 98.94% CS-0040872 5mg $65
More product size
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CeMMEC1 Properties

Boiling point 590.1±50.0 °C(Predicted)
Density 1.386±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form A crystalline solid
pka 11.38±0.20(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

CeMMEC1 price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19956 CeMMEC1 ≥98% 440662-09-9 500μg $36 2026-04-30 Buy
Cayman Chemical 19956 CeMMEC1 ≥98% 440662-09-9 1mg $68 2026-04-30 Buy
Cayman Chemical 19956 CeMMEC1 ≥98% 440662-09-9 5mg $268 2026-04-30 Buy
Cayman Chemical 19956 CeMMEC1 ≥98% 440662-09-9 10mg $469 2026-04-30 Buy
ChemScene CS-0040872 CeMMEC1 98.94% 440662-09-9 5mg $65 2026-06-04 Buy
Product number Packaging Price Buy
19956 500μg $36 Buy
19956 1mg $68 Buy
19956 5mg $268 Buy
19956 10mg $469 Buy
CS-0040872 5mg $65 Buy

CeMMEC1 Chemical Properties,Uses,Production

Description

CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. This compound synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.

Uses

CeMMEC1, shows high affinity for TAF1, and is an inhibitor of BRD4.

storage

Store at -20°C

References

[1] SARA SDELCI. Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk[J]. Nature chemical biology, 2016, 12 7: 504-510. DOI: 10.1038/nchembio.2080

CeMMEC1 Preparation Products And Raw materials

Raw materials

Preparation Products

CeMMEC1 Suppliers

Global( 68)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 factory@coreychem.com China 29780 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
BOC Sciences 		16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 38999 58
Aladdin Scientific 		tp@aladdinsci.com United States 54746 58
Shaanxi Dideu New Materials Co. Ltd 		18192503167 1036@dideu.com China 13233 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4766 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4857 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Supplier Advantage
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Shaanxi Dideu New Materials Co. Ltd 		58
Amadis Chemical Company Limited 		58
Dalian Meilun Biotech Co., Ltd. 58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58

View Lastest Price from CeMMEC1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CeMMEC1 pictures 2026-07-20 CeMMEC1
440662-09-9
 $30.00-116.00 98.90% 10g TargetMol Chemicals Inc.
CeMMEC1 pictures 2026-07-01 CeMMEC1
440662-09-9
 1KG 98% 20Tons Shaanxi Dideu New Materials Co. Ltd
CeMMEC1 pictures 2020-01-10 CeMMEC1
440662-09-9
 1KG 98%; 99% 500g;1kg； 25kg Career Henan Chemical Co
  • CeMMEC1 pictures
  • CeMMEC1
    440662-09-9
  • $30.00-116.00
  • 98.90%
  • TargetMol Chemicals Inc.
  • CeMMEC1 pictures
  • CeMMEC1
    440662-09-9
  • $0.00
  • 98%
  • Shaanxi Dideu New Materials Co. Ltd
  • CeMMEC1 pictures
  • CeMMEC1
    440662-09-9
  • $0.01
  • 98%; 99%
  • Career Henan Chemical Co

CeMMEC1 Spectrum

CeMMEC1(440662-09-9)1HNMR

440662-09-9(CeMMEC1)Related Search:

1(2H)-Isoquinolinone, 2-ethyl-6,7-dimethoxy-4-[(4-methyl-1-piperazinyl)carbonyl]- N,N-DIMETHYL-1-OXO-2-PHENYL-1,2-DIHYDRO-4-ISOQUINOLINECARBOXAMIDE NA N-METHYL-1-OXO-2-PHENYL-1,2-DIHYDRO-4-ISOQUINOLINECARBOXAMIDE CeMMEC1 hydrochloride
2-ethyl-4-[(4-ethyl-1-piperazinyl)carbonyl]-6,7-dimethoxy-1(2H)-Isoquinolinone

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CeMMEC1 cemmecl CeMMEC1(free base) 4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo- Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1 N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide CeMMEC1, 10 mM in DMSO CeMMEC1 (CeMMEC 1) 440662-09-9