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Norverapamil hydrochloride

CAS No.
67812-42-4
Chemical Name:
Norverapamil hydrochloride
Synonyms
NORVERAPAMIL HCL;D591 hydrochloride;Verapamil EP Impurity J;Verapamil Impurity J HCl;Norverapamil hydrochloride;Verapamil EP Impurity J HCl;(+)Norverapamil hydrochloride;(±)-Norverapamil hydrochloride;(+/-)-Norverapamil hydrochloride;n-nor-(±)-verapamil hydrochloride
CBNumber:
CB8331256
Molecular Formula:
C26H37ClN2O4
Molecular Weight:
477.04
MDL Number:
MFCD00078605
MOL File:
67812-42-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:38

Norverapamil hydrochloride Properties

Melting point softens at 50°C, 155-160°C dec.
Flash point 9℃
storage temp. desiccated
solubility H2O: >10 mg/mL
form solid
color white
Water Solubility H2O: 15mg/mL, clear
Stability Hygroscopic
InChI 1S/C26H36N2O4.ClH/c1-19(2)26(18-27,21-9-11-23(30-4)25(17-21)32-6)13-7-14-28-15-12-20-8-10-22(29-3)24(16-20)31-5;/h8-11,16-17,19,28H,7,12-15H2,1-6H3;1H
InChIKey OEAFTRIDBHSJDC-UHFFFAOYSA-N
SMILES CC(C)C(CCCNCCC1=CC=C(OC)C(OC)=C1)(C#N)C2=CC(OC)=C(OC)C=C2.Cl
EPA Substance Registry System Benzeneacetonitrile, .alpha.-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-, hydrochloride (1:1) (67812-42-4)
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type N95 (US)
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

Norverapamil hydrochloride price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich V108 (±)-Norverapamil hydrochloride ≥98% (HPLC) 67812-42-4 5mg $361 2026-04-30 Buy
Sigma-Aldrich N-112 (±)-Norverapamill hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 67812-42-4 1mL $150 2022-05-15 Buy
Cayman Chemical 20950 Norverapamil (hydrochloride) ≥98% 67812-42-4 1mg $36 2026-04-30 Buy
Cayman Chemical 20950 Norverapamil (hydrochloride) ≥98% 67812-42-4 5mg $153 2026-04-30 Buy
Cayman Chemical 20950 Norverapamil (hydrochloride) ≥98% 67812-42-4 10mg $268 2026-04-30 Buy
Product number Packaging Price Buy
V108 5mg $361 Buy
N-112 1mL $150 Buy
20950 1mg $36 Buy
20950 5mg $153 Buy
20950 10mg $268 Buy

Norverapamil hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Off-White Crystalline Solid

Uses

Nor Verapamil Hydrochloride (Verapamil EP Impurity J HCl) is a metabolite of Verapamil.

General Description

Norverapamil is a primary urinary metabolite of verapamil, a calcium channel blocker used in the treatment of hypertension, angina pectoris, and cardiac arrhythmia. Verapamil is also an effective preventive medication for migraines. This Certified Reference Material is applicable for use as starting material in calibrators or controls for verapamil testing methods by LC-MS/MS or GC-MS.

Biochem/physiol Actions

Norverapamil is an N-demethylated metabolite of verapamil. It has significantly less calcium channel blocking ability and exhibit therapeutic activity.

Norverapamil hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 110)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412 3001272453@qq.com China 5000 50
Acesys Pharmatech 18860950986 tangmanman@zenjipharma.com China 1731 55
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9656 58
Cato Research Chemicals Inc. 020-81960175 min.he@cato-chem.com China 1949 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
BOC Sciences 16314854226 info@bocsci.com United States 9909 65
Artis Biotech Co. Ltd. 18108108965 18108108965 sales@artisbio.com China 2503 58

View Lastest Price from Norverapamil hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Norverapamil hydrochloride pictures 2026-07-27 Norverapamil hydrochloride
67812-42-4
$113.00-332.00 99.63% 10g TargetMol Chemicals Inc.
NORVERAPAMIL HYDROCHLORIDE pictures 2021-07-13 NORVERAPAMIL HYDROCHLORIDE
67812-42-4
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
NORVERAPAMIL HYDROCHLORIDE pictures 2021-07-10 NORVERAPAMIL HYDROCHLORIDE
67812-42-4
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

Norverapamil hydrochloride Spectrum

NORVERAPAMIL HCL (+/-)-VERAPAMIL, NOR-METHYL-, HYDROCHLORIDE a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-a-(1-methylethyl)- benzeneacetonitril n-nor-(±)-verapamil hydrochloride α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)- benzeneacetonitrile (+-)-VERAPAMIL HYDROCHLORIDE, NOR-METHYL (NORVERAPAMIL HYDROCH a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile NorverapaMil HCl (N-DesMethyl VerapaMil HCl) (±)-Norverapamill hydrochloride solution Verapamil Impurity J HCl (±)-NORVERAPAMIL HYDROCHLORIDE;D591 HYDROCHLORIDE D591 hydrochloride 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-propan-2-ylpentanenitrile,hydrochloride Verapamil EP Impurity J Verapamil Impurity 10(Verapamil EP Impurity J) Verapamil EP Impurity J HCl (N-Desmethyl Verapamil HCl) (+/-)-Norverapamil hydrochloride (+/-)-Norverapamill hydrochloride solution Verapamil EP Impurity J HCl Norverapamil HydrochlorideQ: What is Norverapamil Hydrochloride Q: What is the CAS Number of Norverapamil Hydrochloride Q: What is the storage condition of Norverapamil Hydrochloride Q: What are the applications of Norverapamil Hydrochloride MDR1,CD243,Inhibitor,mycobacterial,Norverapamil,M. tuberculosis,Multidrug resistance protein 1,Ca2+ channels,metabolite,(±)-Norverapamil,P-gp,Calcium Channel,efflux,Ca channels,Drug Metabolite,P-glycoprotein,inhibit,ABCB1,Cluster of differentiation 243,D 591,Norverapamil hydrochloride,pumps,D-591,D591,Pgp (+)Norverapamil hydrochloride Norverapamil hydrochloride, 10 mM in DMSO (±)-Norverapamil hydrochloride (±)-Norverapamill hydrochloride solution (RS)-5-((3,4-dimethoxyphenethyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile Verapamil EP Impurity J HCl (N-Desmethyl Verapamil HCl, Norverapamil HCl) Norverapamil hydrochloride (Standard) Norverapamil hydrochloride 67812-42-4 670018-85-3 C26H36N2O4HCl Ion Channels Voltage-gated Ion Channels Cell Signaling and Neuroscience Cell Biology Calcium Channel Modulators BioChemical Metabolites Various Metabolites and Impurities