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N-(Azido-PEG3)-N-Boc-PEG3-acid

CAS No.
2112731-52-7
Chemical Name:
N-(Azido-PEG3)-N-Boc-PEG3-acid
Synonyms
CUN 31527;N-(Azido-PEG3)-N-Boc-PEG3-acid;Boc-(N3-PEG3-CH2CH2)N-PEG3-CH2CH2COOH;1-Azido-12-(tert-butoxycarbonyl)-3,6,9,15,18,21-hexaoxa-12-azatetracosan-24-oic acid;5,8,11-Trioxa-2-azatetradecanedioic acid, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-, 1-(1,1-dimethylethyl) ester
CBNumber:
CB83373691
Molecular Formula:
C22H42N4O10
Molecular Weight:
522.58968
MDL Number:
MFCD30723234
MOL File:
2112731-52-7.mol
MSDS File:
SDS
Last updated:2026-05-28 05:51:45

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

N-(Azido-PEG3)-N-Boc-PEG3-acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0115283 N-(Azido-PEG3)-N-Boc-PEG3-acid ≥98% 2112731-52-7 100mg $233 2026-06-04 Buy
ChemScene CS-0115283 N-(Azido-PEG3)-N-Boc-PEG3-acid ≥98% 2112731-52-7 250mg $529 2026-06-04 Buy
ChemScene CS-0115283 N-(Azido-PEG3)-N-Boc-PEG3-acid ≥98% 2112731-52-7 1g $1484 2026-06-04 Buy
BroadPharm bp-23569 N-(Azido-PEG3)-N-Boc-PEG3-acid 95% 2112731-52-7 100MG $320 2026-05-24 Buy
BroadPharm bp-23569 N-(Azido-PEG3)-N-Boc-PEG3-acid 95% 2112731-52-7 250MG $650 2026-05-24 Buy
Product number Packaging Price Buy
CS-0115283 100mg $233 Buy
CS-0115283 250mg $529 Buy
CS-0115283 1g $1484 Buy
bp-23569 100MG $320 Buy
bp-23569 250MG $650 Buy

N-(Azido-PEG3)-N-Boc-PEG3-acid Chemical Properties, Uses, Production

Description

N-(Azido-PEG3)-N-Boc-PEG3-acid enable Click Chemistry with alkyne such as Propargyl, BCN or DBCO reagent. Boc group can be deprotected under acidic conditions. The terminal carboxylic acid can react with primary amino groups in the presence of EDCor HATU.

Uses

N-(Azido-PEG3)-N-Boc-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-Boc-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Azido-PEG3)-N-Boc-PEG3-acid Preparation Products And Raw materials

Raw materials

Preparation Products

N-(Azido-PEG3)-N-Boc-PEG3-acid Suppliers

Global Suppliers ( 21)
Supplier Tel Email Country ProdList Advantage
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80534353 19917294565 et@chemextension.com China 3904 55
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28760 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-025-66113011 15955137747 cb5@aikonchem.com China 10354 58
Nanjing Bairuikang Biotechnology Co., Ltd. 18168036974 wangweicss@126.com China 1379 58
Shandong fen Boyu Biotechnology Co.,LTD 13356310019 13356310019; boyu2024@163.com China 3947 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58

View Latest Price from N-(Azido-PEG3)-N-Boc-PEG3-acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-(Azido-PEG3)-N-Boc-PEG3-acid pictures 2025-06-07 N-(Azido-PEG3)-N-Boc-PEG3-acid
2112731-52-7
500mg >95.00% 500mg Xian confluore Biological Technology Co., Ltd.
N-(Azido-PEG3)-N-Boc-PEG3-acid CUN 31527 5,8,11-Trioxa-2-azatetradecanedioic acid, 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-, 1-(1,1-dimethylethyl) ester Boc-(N3-PEG3-CH2CH2)N-PEG3-CH2CH2COOH 1-Azido-12-(tert-butoxycarbonyl)-3,6,9,15,18,21-hexaoxa-12-azatetracosan-24-oic acid 2112731-52-7