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Lithium orotate

CAS No.
5266-20-6
Chemical Name:
Lithium orotate
Synonyms
Lithium orotate;lithium 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate;C5H5LiN2O4;Lithium whorate;Orotic acid lithium salt;Lithiiorotasmonohydricum;OROTIC ACID LITHIUM SALT MONOHYDRATE;Orotic acid monohydrate lithium salt;lithium,2,4-dioxo-1H-pyrimidine-6-carboxylate;Lithium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate
CBNumber:
CB8360076
Molecular Formula:
C5H5LiN2O4
Molecular Weight:
164.05
MDL Number:
MFCD00167174
MOL File:
5266-20-6.mol
MSDS File:
SDS
Last updated:2026-06-24 09:49:51
Product description Number Pack Size Price
Lithium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate 297133 1.00g $60
Lithium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate 297133 5.00g $180
Lithium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate 297133 25.00g $535
Lithium orotate 95% AA00DE65 250mg $42
Lithium orotate ≥95% AA00DE65 5g $263
More product size

Lithium orotate Properties

Melting point ≥300 °C
InChI InChI=1S/C5H4N2O4.Li.H/c8-3-1-2(4(9)10)6-5(11)7-3;;/h1H,(H,9,10)(H2,6,7,8,11);;
InChIKey VGCZUEFPIFEVJF-UHFFFAOYSA-N
SMILES C(C1NC(=O)NC(=O)C=1)(=O)O.[LiH]
FDA UNII L2N7Z24B30
EPA Substance Registry System 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, monolithium salt (5266-20-6)

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
TSCA  TSCA listed

Lithium orotate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 297133 Lithium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate 5266-20-6 1.00g $60 2026-05-19 Buy
Matrix Scientific 297133 Lithium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate 5266-20-6 5.00g $180 2026-05-19 Buy
Matrix Scientific 297133 Lithium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate 5266-20-6 25.00g $535 2026-05-19 Buy
aablocks AA00DE65 Lithium orotate 95% 5266-20-6 250mg $42 2026-05-28 Buy
aablocks AA00DE65 Lithium orotate ≥95% 5266-20-6 5g $263 2026-05-28 Buy
Product number Packaging Price Buy
297133 1.00g $60 Buy
297133 5.00g $180 Buy
297133 25.00g $535 Buy
AA00DE65 250mg $42 Buy
AA00DE65 5g $263 Buy

Lithium orotate Chemical Properties,Uses,Production

Description

Lithium orotate (LiOr) is a salt composed of orotic acid and lithium, and serves as a superior alternative to lithium carbonate in lithium therapy. As a dietary supplement, LiOr is used for mood regulation, cognitive enhancement, and brain protection, and plays an important role in the prevention and treatment of bipolar disorder (BD). Studies have shown that LiOr crosses the blood-brain barrier and enters cells more easily than lithium carbonate, meaning that LiOr is more potent and requires lower doses[1].

Chemical Properties

Lithium orotate, also known as vitamin B13. White shiny needle-like crystals or crystalline powder obtained from water, odorless and sour. The melting point was 345-346 °c. Insoluble in cold water and ethanol, slightly soluble in hot water.

Uses

Lithium orotate is a nutritional supplement form of lithium, used in micro doses much like zinc or selenium.

Purification Methods

The salt is soluble in H2O at 17o and 100o. Best to acidify an aqueous solution of the salt, isolate the free acid (see above) which is recrystallised from H2O (as monohydrate) m 345-347o (345-346o), then dissolve it in EtOH, add an equivalent amount of LiOH in EtOH and evaporate. Its solubility in H2O is 1.28% (17o) and 2.34% (100o). [Bachstez Chem Ber 63 1000 1930, Johnson & Shroeder J Am Chem Soc 54 2941 1932, UV: Shugar & Fox Biochim Biophys Acta 9 199 1952, Beilstein 25 III/IV 1759.]

References

[1] Anthony G. Pacholko, Lane K. B. (2021). Lithium orotate: A superior option for lithium therapy? Brain and Behavior, 11 8. https://doi.org/10.1002/brb3.2262

Lithium orotate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 157)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong Natural Micron Pharm Tech Co.,LTD
+86-18653895227 info@nmpharmtech.com China 94 58
Hydebio Labs Co.,Limited
+86-18100690299 +86-18100690299 mrkt@hydebiolabs.com China 129 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739 info@dycnchem.com China 53799 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81139210 17389186172 1077@dideu.com China 3999 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 3955 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20111 58
Shaanxi Xianhe Biotech Co., Ltd
+86-17709210191; +86-17709210191 Jerry@xhobio.com China 901 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 niki@zlchemi.com China 7240 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21531 55
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19935 58

View Lastest Price from Lithium orotate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lithium orotate pictures 2026-08-07 Lithium orotate
5266-20-6
1KG 99% 1KG 100KG 1MT Shaanxi Dideu Medichem Co. Ltd
				Lithium orotate pictures 2026-08-06 Lithium orotate
5266-20-6
$1.00-6.00 1KG 99% Henan Fengda Chemical Co., Ltd
Lithium orotate pictures 2026-08-06 Lithium orotate
5266-20-6
1kg 98.5%min 20tons HANGZHOU HAILAN CHEMICAL CO.,LTD.
orotic acid lithium salt monohydrate 5266-20-6 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid lithium salt Orotic acid lithium salt 5266-20-6 lithium,2,4-dioxo-1H-pyrimidine-6-carboxylate 1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicacimonolithiumsalt OROTIC ACID LITHIUM SALT MONOHYDRATE Lithiiorotasmonohydricum Lithium orotate Orotic acid monohydrate lithium salt 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid lithium salt Orotic acid lithium salt 4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-, lithium salt Lithium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate Lithium whorate lithium 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate C5H5LiN2O4 5266-20-6 85266-20-6 C5H5LiN2O5 C5H3N2O4Li C5H3LiN2O4H2O