PAF (C18)
- CAS No.
- 74389-69-8
- Chemical Name:
- PAF (C18)
- Synonyms
- C18 PAF;PAF (C18);ro14-8161;C18-02:0 PC;PAF (C18),99%;c18-paf-acether;PLATELET ACTIVATING FACTOR-18;PLATELET ACTIVATING FACTOR (C18);hydroxide,innersalt,4-oxide,(r)-thyl;1-O-STEARYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- CBNumber:
- CB8371788
- Molecular Formula:
- C28H58NO7P
- Molecular Weight:
- 551.74
- MDL Number:
- MFCD00063528
- MOL File:
- 74389-69-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| PAF C-18 ≥97% | 60910 | 1mg | $55 |
| PAF C-18 ≥97% | 60910 | 5mg | $165 |
| PAF C-18 ≥97% | 60910 | 10mg | $248 |
| PAF C-18 ≥97% | 60910 | 25mg | $413 |
| PAF C-18 ≥97% | 60910 | 5mg | $70 |
| storage temp. | -20°C |
|---|---|
| solubility | chloroform: 10 mg/mL |
| form | powder |
| color | White to off-white |
| InChI | 1S/C28H58NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3,4)5/h28H,6-26H2,1-5H3/t28-/m1/s1 |
| InChIKey | ZXCIEWBDUAPBJF-MUUNZHRXSA-N |
| SMILES | [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCCCC)=O |
| FDA UNII | C9ZA6E5Q2B |
| UNSPSC Code | 12352211 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| HS Code | 29310099 |
| Storage Class | 11 - Combustible Solids |
PAF (C18) price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 60910 | PAF C-18 ≥97% | 74389-69-8 | 1mg | $55 | 2026-04-30 | Buy |
| Cayman Chemical | 60910 | PAF C-18 ≥97% | 74389-69-8 | 5mg | $165 | 2026-04-30 | Buy |
| Cayman Chemical | 60910 | PAF C-18 ≥97% | 74389-69-8 | 10mg | $248 | 2026-04-30 | Buy |
| Cayman Chemical | 60910 | PAF C-18 ≥97% | 74389-69-8 | 25mg | $413 | 2026-04-30 | Buy |
| Cayman Chemical | 60910 | PAF C-18 ≥97% | 74389-69-8 | 5mg | $70 | 2024-03-01 | Buy |
PAF (C18) Chemical Properties,Uses,Production
Chemical Properties
white solid
Uses
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine is suitable as a substrate for enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.
Uses
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.
Definition
ChEBI: 2-acyl-1-alkyl-sn-glycero-3-phosphocholine betaine in which the 1-alkyl and 2-acyl groups are specified as octacdecyl and acetyl respectively
General Description
C18-02:0 PC, also known as 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18∶0-PAF), is a platelet-activating factor lipid. It belongs to a class of natural PAFs and is produced in basophil leucocytes, macrophages, polymorphonuclear neutrophils and monocytes and platelets.
Biochem/physiol Actions
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18-PAF), a platelet-activating factor (PAF) facilitates platelet aggregation and secretion. It also plays a key role in inflammation and anaphylaxis. C18-PAF exhibits neurotoxic effects by initiating caspase-independent death in PAF receptor-deficient neurons.
PAF (C18) Preparation Products And Raw materials
Raw materials
Preparation Products
PAF (C18) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17770 | 75 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29974 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Codow Chemical Co.,Ltd. | -- | amy@howeipharm.com | China | 6687 | 55 |
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