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ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER

CAS No.
21085-72-3
Chemical Name:
ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER
Synonyms
(2R,3R,4S,5S,6S)-2-BroMo-6-(Methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate;Bromo-2,3,4-tri-O-acetyl-α-d-glucopyranuronic Acid Methyl Ester;Methyl acetobromo-α-D-glucuronate;METHYL ACETOBROMO-ALPHA-D-GLUCURONATE;acetobromo-α-d-glucuronic acid methyl ester;EOS-61715;Acetobromo-aL;Einecs 244-203-4;ucuronicacidmethyL;Methyl α-Acetobromoglucuronate
CBNumber:
CB8396406
Molecular Formula:
C13H17BrO9
Molecular Weight:
397.17
MDL Number:
MFCD00061613
MOL File:
21085-72-3.mol
MSDS File:
SDS
Last updated:2026-01-13 11:26:22
Product description Number Pack Size Price
Acetobromo-α-D-glucuronic acid methyl ester ≥93% A8292 1g $272
Acetobromo-α-D-glucuronic acid methyl ester ≥93% A8292 5g $929
Acetobromo-α-D-glucuronic Acid Methyl Ester min. 95.0 % A3379 1G $36
Acetobromo-a-D-glucuronic Acid, Methyl Ester A0200-89 2g $403
Acetobromo-α-D-glucuronicAcidMethylEster(contains2%CaCO3) A162000 5g $275
More product size

ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Properties

Melting point 80-110 °C(lit.)
Boiling point 388.6±42.0 °C(Predicted)
Density 1.52
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Acetonitrile (Slightly), Chloroform (Slightly, Heated, Sonicated), Dichlorometha
form Crystalline Powder or Solid
color White to gray
optical activity [α]/D 188 to 198 °, c =1% (w/v) in ethyl acetate
BRN 96281
Stability Moisture and Temperature Sensitive
InChI InChI=1/C13H17BrO9/c1-5(15)20-8-9(21-6(2)16)11(13(18)19-4)23-12(14)10(8)22-7(3)17/h8-12H,1-4H3/t8-,9-,10+,11-,12-/s3
InChIKey BCDVKFMSIQGEHB-CIQUZCHMSA-N
SMILES O([C@@H]1[C@H]([C@@H](Br)O[C@H](C(=O)OC)[C@H]1OC(=O)C)OC(=O)C)C(=O)C |&1:1,2,3,6,11,r|
CAS DataBase Reference 21085-72-3(CAS DataBase Reference)
UNSPSC Code 12352201
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25
WGK Germany  3
3-8-10-21
Hazard Note  Irritant/Store Cold under -20oC
HS Code  29189900
Storage Class 11 - Combustible Solids

ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A8292 Acetobromo-α-D-glucuronic acid methyl ester ≥93% 21085-72-3 1g $272 2025-07-31 Buy
Sigma-Aldrich A8292 Acetobromo-α-D-glucuronic acid methyl ester ≥93% 21085-72-3 5g $929 2025-07-31 Buy
TCI Chemical A3379 Acetobromo-α-D-glucuronic Acid Methyl Ester min. 95.0 % 21085-72-3 1G $36 2025-07-31 Buy
Usbiological A0200-89 Acetobromo-a-D-glucuronic Acid, Methyl Ester 21085-72-3 2g $403 2021-12-16 Buy
TRC A162000 Acetobromo-α-D-glucuronicAcidMethylEster(contains2%CaCO3) 21085-72-3 5g $275 2021-12-16 Buy
Product number Packaging Price Buy
A8292 1g $272 Buy
A8292 5g $929 Buy
A3379 1G $36 Buy
A0200-89 2g $403 Buy
A162000 5g $275 Buy

ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Chemical Properties,Uses,Production

Uses

Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of HMR1098-S-glucuronide methyl ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.
Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of water-soluble glucuronide derivatives of Camptothecin, which is used for cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy (ADEPT).
Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of glucuronide prodrug compounds of Janus kinase (JAK) inhibitor tofacitinib, which could be cleaved by β-glucuronidase enzymes such as those produced by the microbiome in the gastrointestinal tract, thereby increasing levels of tofacitinib at the site of gastrointestinal inflammation and limiting the systemic exposure of tofacitinib when treating localized inflammatory diseases.

Chemical Properties

White Crystalline Solid

Uses

Antitumor agent

7355-18-2
21085-72-3
Synthesis of ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER from METHYL 1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCURONATE
Global( 274)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29735 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13799 58
Speranza Chemical Co., Ltd.
+86-86-075521030354 +8618688942810 sophieliu@speranzachem.com China 923 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29831 58
Jinan Samuel Pharmaceutical CO., Ltd
0531-88821801 15192360884 605818151@qq.com CHINA 124 58
Win-Win Chemical CO., Limited
0086-577-64498589 sales@win-winchemical.com CHINA 998 58
Changzhou Ansciep Chemical Co., Ltd.
+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8497 58
Changzhou PBpharmaceutical R&D Co.,Ltd
0519-83990708 info@pbpharm.com CHINA 498 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 21193 58

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View Lastest Price from ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Acetobromo-a-D-glucuronic acid methyl ester pictures 2026-02-13 Acetobromo-a-D-glucuronic acid methyl ester
21085-72-3
US $0.00 / G 1G 98%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Acetobromo-alpha-d-glucuronic acid methyl ester pictures 2022-02-19 Acetobromo-alpha-d-glucuronic acid methyl ester
21085-72-3
US $0.00 / KG 1KG 98.4% 100 tons Honest Joy Holdings Limited
1-Bromo-2,3,4-tri-O-acetyl-α-D-glucuronide methyl ester  pictures 2020-03-26 1-Bromo-2,3,4-tri-O-acetyl-α-D-glucuronide methyl ester
21085-72-3
US $0.00 / g/bag 25g/bag 97%HPLC MG-KG GlycoPharm.LLC
Methyl acetobromo-α-D-glucuronate, Bromo-2,3,4-tri-O-acetyl-α-D-glucopyranuronic acid methyl ester, (2,3,4-Tri-O-acetyl-α-D-glucopyranosyl bromide)uronic acid methyl ester 1-Bromo-1-deoxy-2-O,3-O,4-O-triacetyl-α-D-glucopyranuronic acid methyl ester 2,3,4-Trideoxy-2,3,4-triacetoxy-1-bromo-1-deoxy-α-D-glucopyranuronic acid methyl ester 2-O,3-O,4-O-Triacetyl-1-bromo-1-deoxy-α-D-glucopyranuronic acid methyl ester 2-O,3-O,4-O-Triacetyl-6-O-methyl-6-C-oxo-1-bromo-1-deoxy-α-D-glucopyranose 2-O,3-O,4-O-Triacetyl-6-O-methyl-6-oxo-α-D-glucopyranosyl bromide 6-O-Methyl-2-O,3-O,4-O-triacetyl-α-D-glucopyranuronosyl bromide Einecs 244-203-4 Acetobromo-α-D-glucuronic acid methyl ester ,98% ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER Methyl (3S,4R,6R)-3,4,5-tris(acetoxy)-6-bromotetrahydro-2H-pyran-2-carboxylate Methyl 1-bromo-1-deoxy-2,3,4-tri-O-acetyl-alpha-D-glucopyranuronate Methyl 2,3,4-tri-O-acetyl-1-bromo-1-deoxy-alpha-D-glucopyranosyluronate METHYL ACETOBROMO-ALPHA-D-GLUCURONATE BROMO-2,3,4-TRI-O-ACETYL-ALPHA-D-GLUCOPYRANURONIC ACID METHYL ESTER BROMOMETHYLTRIACETYL GLUCURONATE alpha-d-glucopyranuronicacid,1-bromo-1-deoxy-,methylester,triacetate (2,3,4-TRI-O-ACETYL-ALPHA-D-GLUCOPYRANOSYL BROMIDE)URONIC ACID METHYL ESTER 2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-ALPHA-DGLUCOPYRANOSIDURONIC ACID METHYL ESTER 1-BROMO-1-DEOXY-2,3,4-TRI-0-ACETYL-Α-D-GLUCURONICACID METHYL (2S,3S,4S,5R,6R)-3,4,5-TRIS(ACETYLOXY)-6-BROMOOXANE-2-CARBOXYLATE 1-Bromo-2,3,4-tri-O-acetyl-α-D- glucuronide methyl ester EOS-61715 (2R,3R,4S,5S,6S)-2-BroMo-6-(Methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 1-Bromo-1-deoxy-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester Methyl acetobromo-α-D-glucuronate (2S,3S,4S,5R,6R)-methyl 3,4,5-triacetoxy-6-bromo-tetrahydro-2H-pyran-2-carboxylate (2R,3R,5S)-2-bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 1-Bromo-2,3,4-tri-O-acetyl-a-D-glucuronide methyl ester - 1% CaCO3 Acetobromo-α-D-glucuronic Acid Methyl Ester Α-D 1-Bromo-2,3,4-tri-O-acetyl-α-D-glucuronic Acid Methyl Ester Methyl a-Acetobromoglucuronate Bromo-2,3,4-tri-O-acetyl-a-d-glucopyranuronic Acid Methyl Ester (2,3,4-tri-o-acetyl-α-d-glucopyranosyl bromide)uronic acid methyl ester acetobromo-α-d-glucuronic acid methyl ester 1-Bromo-2,3,4-tri-O-acetyl-a-D-glucuronidemethylester METHYL 2,3,4-TRI-O-ACETYL-1-BROMO-1-DEOXY-A-D-GLUCOPYRANURONATE Acetobromo-alpha-D-glucuronic acid, methyl ester 95+% 1-Bromo-1-deoxy-2,3,4-tri-O-acetyl-ALPHA-D-glucuronide methyl ester Bromo-2,3,4-tri-O-acetyl-α-d-glucopyranuronic Acid Methyl Ester Methyl α-Acetobromoglucuronate ACETOBROMO-A-D-GLUCURONIC ACID, METHYL ESTER methyl tri-O-acetyl-1-bromo-1-deoxy-alpha-D-glucopyranuronate 1-BROMO-2,3,4-TRI-O-ACETYL-ALPHA-D-GLUCURONIC ACID METHYL ESTER Acetobromo-aL ucuronicacidmethyL 2,3,4-Tri-O-acetyl-1-bromo-1-deoxy-α-D-glucopyranuronic acid methyl ester Methyl 2,3,4-Tri-O-acetyl-alpha-D-glucopyranosyluronate Bromide ACETOBROMO-ALPHA-D-GLUCURONIC ACID METHYL ESTER USP/EP/BP Acetobromo-α-D-glucuronic Acid Methyl Ester (contains 2% CaCO3) methyl tri-O-acetyl-1-bromo-1-deoxy-α-D-glucopyranuronate Acetobromo- α-D-glucuronic acid methyl ester Methyl(tri-O-acetyl-α-D-glucopyranosyl bromide)uronate α-D-Glucopyranuronic acid, 1-bromo-1-deoxy-, methyl ester, 2,3,4-triacetate methyl (2S,3S,4S,5R,6R)-3,4,5-triacetoxy-6-bromo-tetrahydropyran-2-carboxylate D-Glucuronic Acid-13C6 Sodium Salt Hydrate Acetobromo-α-D-glucuronic acid methyl ester Acetobromo-α-D-glucuronic acid methyl ester, CAS 21085-72-3