5-Phenyl-2H-pyrazole-3-carboxylic acid ethyl ester
- CAS No.
- 13599-12-7
- Chemical Name:
- 5-Phenyl-2H-pyrazole-3-carboxylic acid ethyl ester
- Synonyms
- SALOR-INT L250031-1EA;Ethyl 3-phenyl-5-pyrazole formate;3-phenypyrazole-5-ethyl carboxylate;Ethyl 3-phenylpyrazole-5-carboxylate;ETHYL 3-PHENYL-1H-PYRAZOLE-5-CARBOXYLATE;5-Phenyl-2H-pyrazole-3-carboxylic acid ethyl ester;5-phenyl-1(2)H-pyrazole-3-carboxylic acid ethyl ester;1H-pyrazole-5-carboxylic acid, 3-phenyl-, ethyl ester
- CBNumber:
- CB8400284
- Molecular Formula:
- C12H12N2O2
- Molecular Weight:
- 216.24
- MDL Number:
- MFCD03130041
- MOL File:
- Mol file
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 24/25 |
| HazardClass | IRRITANT |
| HS Code | 29331990 |
5-Phenyl-2H-pyrazole-3-carboxylic acid ethyl ester price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | NAA59912 | Ethyl 3-phenyl-1H-pyrazole-5-carboxylate | 13599-12-7 | 5g | $900 | 2026-06-04 | Buy |
| Biosynth | NAA59912 | Ethyl 3-phenyl-1H-pyrazole-5-carboxylate | 13599-12-7 | 2g | $900 | 2026-06-04 | Buy |
| Biosynth | NAA59912 | Ethyl 3-phenyl-1H-pyrazole-5-carboxylate | 13599-12-7 | 1g | $900 | 2026-06-04 | Buy |
| Biosynth | NAA59912 | Ethyl 3-phenyl-1H-pyrazole-5-carboxylate | 13599-12-7 | 10g | $900 | 2026-06-04 | Buy |
| Biosynth | NAA59912 | Ethyl 3-phenyl-1H-pyrazole-5-carboxylate | 13599-12-7 | 0.5g | $900 | 2026-06-04 | Buy |
5-Phenyl-2H-pyrazole-3-carboxylic acid ethyl ester Chemical Properties, Uses, Production
Chemical Properties
White solid
Synthesis
98-86-2
95-92-1
13599-12-7
A mixed solution of acetophenone (100 g) with diethyl oxalate (123 g) was added slowly and dropwise to a mixed system of potassium tert-butoxide (132 g) and tetrahydrofuran (600 mL), and the reaction was stirred at room temperature for 15 hours. Subsequently, acetic acid (119 mL) and hydrazine monohydrate (45.8 g) were added to the reaction system and stirred at reflux for 2 hours. After completion of the reaction, the reaction solution was cooled to room temperature and concentrated under reduced pressure. The concentrated residue was dissolved in a solvent mixture of water and ethyl acetate for partition extraction. The ethyl acetate layer was separated, washed sequentially with saturated aqueous sodium carbonate and saturated saline, dried over anhydrous magnesium sulfate and concentrated. The resulting crude product was recrystallized by diisopropyl ether to give ethyl 3-phenyl-1H-pyrazole-5-carboxylate (145 g, yield: brown solid). The product was characterized by 1H-NMR (300 MHz, CDCl3): δ 1.36 (3H, t, J = 7.2 Hz), 4.36 (2H, q, J = 7.2 Hz), 7.10 (1H, s), 7.30-7.46 (3H, m), 7.71-7.80 (2H, m), 11.86 (1H, br s).
References
[1] Patent: WO2007/18314, 2007, A2. Location in patent: Page/Page column 115
5-Phenyl-2H-pyrazole-3-carboxylic acid ethyl ester Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
5-Phenyl-2H-pyrazole-3-carboxylic acid ethyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Pharmsynth Pharmaceutical (Chengdu) Technology Co.,LTD | 15528092102 | Pharmsynth@hotmail.com | China | 116 | 60 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Jiaxing Novartis Chemical Co., Ltd. | 18957373295 | China | 1579 | 58 | |
| Changsha Luxing Bio-Chem Technology Co., Ltd. | 0731-88827538 15574813303 | luxingbc@126.com | China | 1975 | 65 |
| Zhengzhou Alfachem Co., Ltd. | 0371-53765687 18937137882 | 3969243885@qq.com | China | 7734 | 55 |
| Nanjing Chemcn Pharmaceutical Co., Ltd. | 18114022054; 18114022054 | 3317707757@qq.com | China | 301 | 55 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Pingguo Pharmaceutical Co., Ltd. | 021-20432229 | 2412110556@qq.com | China | 6016 | 55 |
