ChemicalBook >> CAS DataBase List >>2-Methylamino-3-nitro-6-chloropyridine

2-Methylamino-3-nitro-6-chloropyridine

CAS No.
33742-70-0
Chemical Name:
2-Methylamino-3-nitro-6-chloropyridine
Synonyms
2-METHYLAMINO-3-NITRO-6-CHLORO;2-Chloro-5-nitro-6-methylaminopyridine;2-Methylamino-3-nitro-6-chloropyridine;6-Chloro-N-methyl-3-nitro-2-pyridinamine;2-Chloro-6-(methylamino)-5-nitropyridine;6-Chloro-2-(methylamino)-3-nitropyridine;6-Chloro-2-(N-methylamino)-3-nitropyridine;2-PYRIDINAMINE, 6-CHLORO-N-METHYL-3-NITRO-;Pyridine, 6-chloro-2-(methylamino)-3-nitro-;(6-Chloro-3-nitro-pyridin-2-yl)-Methyl-aMine
CBNumber:
CB8421232
Molecular Formula:
C6H6ClN3O2
Molecular Weight:
187.58
MDL Number:
MFCD08460164
MOL File:
33742-70-0.mol
MSDS File:
SDS
Last updated:2026-05-28 05:12:12
Product description Number Pack Size Price
2-Chloro-5-nitro-6-methylaminopyridine 95% OR345079 1g $102
6-Chloro-N-methyl-3-nitropyridin-2-amine 126420 1.00g $432
6-Chloro-N-methyl-3-nitropyridin-2-amine 126420 5.00g $1350
6-Chloro-N-methyl-3-nitropyridin-2-amine 95+% C42818 100mg $22
6-Chloro-N-methyl-3-nitropyridin-2-amine 95+% C42818 250mg $26

2-Methylamino-3-nitro-6-chloropyridine Properties

Melting point 114 °C
Boiling point 330 °C
Density 1.489
Flash point 153 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka -0.67±0.10(Predicted)
Appearance White to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338
HS Code  2933399990

2-Methylamino-3-nitro-6-chloropyridine price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR345079 2-Chloro-5-nitro-6-methylaminopyridine 95% 33742-70-0 1g $102 2026-06-04 Buy
Matrix Scientific 126420 6-Chloro-N-methyl-3-nitropyridin-2-amine 33742-70-0 1.00g $432 2026-05-18 Buy
Matrix Scientific 126420 6-Chloro-N-methyl-3-nitropyridin-2-amine 33742-70-0 5.00g $1350 2026-05-18 Buy
Synthonix C42818 6-Chloro-N-methyl-3-nitropyridin-2-amine 95+% 33742-70-0 100mg $22 2026-05-06 Buy
Synthonix C42818 6-Chloro-N-methyl-3-nitropyridin-2-amine 95+% 33742-70-0 250mg $26 2026-05-06 Buy
Product number Packaging Price Buy
OR345079 1g $102 Buy
126420 1.00g $432 Buy
126420 5.00g $1350 Buy
C42818 100mg $22 Buy
C42818 250mg $26 Buy

2-Methylamino-3-nitro-6-chloropyridine Chemical Properties,Uses,Production

Synthesis

2,6-Dichloro-3-nitropyridine

16013-85-7

Methylamine

74-89-5

2-Methylamino-3-nitro-6-chloropyridine

33742-70-0

General procedure for the synthesis of 2-methylamino-3-nitro-6-chloropyridine (9) from 2,6-dichloro-3-nitropyridine (8) (2.0 g, 10.4 mmol) and monomethylamine: 2,6-dichloro-3-nitropyridine (8) and sodium carbonate (2.75 g, 25.9 mmol) were suspended in ethanol (100 mL). Subsequently, methylamine solution (7.8 mL, 15.6 mmol, 2M) was added to the suspension and the resulting mixture was stirred and reacted for 3 hours at room temperature. Upon completion of the reaction, the yellow reaction solution was concentrated under reduced pressure and the residue was dissolved in ethyl acetate and washed sequentially with sodium bicarbonate solution and saturated brine. The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The resulting yellow solid was purified by recrystallization from ethanol to afford the target product 6-chloro-N-methyl-3-nitropyridin-2-amine (9) as a yellow solid (1.6 g, 82% yield). Mass spectrum (MS) m/z (M+H): calculated value=187.6; measured value=187.1. 1H NMR (400MHz, DMSO-d6): δ3.00 (3H, d, J=5.1Hz), 6.77 (1H, d, J=8.1Hz), 8.42 (1H, d, J=8.1Hz), 8.72 (1H, m).

References

[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 16, p. 3052 - 3066
[2] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 4, p. 1260 - 1264
[3] ACS Medicinal Chemistry Letters, 2016, vol. 7, # 3, p. 312 - 317
[4] Patent: US2014/349990, 2014, A1. Location in patent: Paragraph 1013; 1014
[5] Patent: WO2014/191896, 2014, A1. Location in patent: Page/Page column 209

2-Methylamino-3-nitro-6-chloropyridine Preparation Products And Raw materials

2-Methylamino-3-nitro-6-chloropyridine Suppliers

Global( 90)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8497 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
career henan chemical co
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Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited
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Baoji Guokang Healthchem Co., Ltd.
+86-0917-3909592 +86-13892490616 gksales1@gk-bio.com China 9071 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Labnetwork lnc.
+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58

View Lastest Price from 2-Methylamino-3-nitro-6-chloropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methylamino-3-nitro-6-chloropyridine pictures 2025-11-18 2-Methylamino-3-nitro-6-chloropyridine
33742-70-0
$1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Methylamino-3-nitro-6-chloropyridine pictures 2021-07-13 2-Methylamino-3-nitro-6-chloropyridine
33742-70-0
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
2-Methylamino-3-nitro-6-chloropyridine pictures 2020-01-09 2-Methylamino-3-nitro-6-chloropyridine
33742-70-0
$1.00 1KG 99% 1000kgs Career Henan Chemical Co

2-Methylamino-3-nitro-6-chloropyridine Spectrum

6-Chloro-2-(N-methylamino)-3-nitropyridine (6-Chloro-3-nitro-pyridin-2-yl)-Methyl-aMine Pyridine, 6-chloro-2-(methylamino)-3-nitro- 2-PYRIDINAMINE, 6-CHLORO-N-METHYL-3-NITRO- 2-Methylamino-3-nitro-6-chloropyridine 2-Chloro-6-(methylamino)-5-nitropyridine 6-Chloro-N-methyl-3-nitro-2-pyridinamine 2-METHYLAMINO-3-NITRO-6-CHLORO 6-Chloro-2-(methylamino)-3-nitropyridine 2-Methylamino-3-nitro-6-chloropyridine ISO 9001:2015 REACH 2-Chloro-5-nitro-6-methylaminopyridine 33742-70-0 Heterocycle-Pyridine series