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Trifluoromethanesulfonyl fluoride

CAS No.
335-05-7
Chemical Name:
Trifluoromethanesulfonyl fluoride
Synonyms
PFC-MSF;Trifluorometansulfonyl fluoride;trifluoromethylsulfonylfluoride;trifluoro-methanesulfonylfluorid;Trifluoromethanesulfonyl fluoride;TRIFLUOROMETHANESULPHONYL FLUORIDE;methanesulfonylfluoride,trifluoro-;Trifluoromethanesulphonylfluoride99%;Trifluoromethanesulphonyl fluoride 99%;Trifluoromethanesulfonic acid fluoride
CBNumber:
CB8449496
Molecular Formula:
CF4O2S
Molecular Weight:
152.07
MDL Number:
MFCD00042402
MOL File:
335-05-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:43

Trifluoromethanesulfonyl fluoride Properties

Boiling point -25°C
Density 1.729±0.06 g/cm3(Predicted)
CAS DataBase Reference 335-05-7(CAS DataBase Reference)
EPA Substance Registry System Methanesulfonyl fluoride, trifluoro- (335-05-7)

SAFETY

Risk and Safety Statements

Hazard Codes  T
Risk Statements  20-34
Safety Statements  26-36/37/39
RIDADR  3308
TSCA  TSCA listed
HazardClass  GAS, TOXIC

Trifluoromethanesulfonyl fluoride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
SynQuest Laboratories 6162-2-01 Trifluoromethanesulfonyl fluoride 98% 335-05-7 100g $495 2026-05-22 Buy
SynQuest Laboratories 6162-2-01 Trifluoromethanesulfonyl fluoride 98% 335-05-7 25g $790 2021-12-16 Buy
Matrix Scientific 004450 Trifluoromethanesulfonyl fluoride 98% 335-05-7 25g $850 2021-12-16 Buy
American Custom Chemicals Corporation HCH0027318 TRIFLUOROMETHANESULFONYL FLUORIDE 95.00% 335-05-7 25G $1380.23 2021-12-16 Buy
Product number Packaging Price Buy
6162-2-01 100g $495 Buy
6162-2-01 25g $790 Buy
004450 25g $850 Buy
HCH0027318 25G $1380.23 Buy

Trifluoromethanesulfonyl fluoride Chemical Properties, Uses, Production

Preparation

103 g (1.78 mol) of 1% aqueous potassium fluoride was fed into a 500 mL pressure-resistant reaction vessel, cooled to 5°C with ice water, and degassed under vacuum. 100 g (0.595 mol) of trifluoromethanesulfonyl chloride was added. The reactor was sealed and the temperature was slowly increased, and stirred for 4 hours at an internal temperature of 40–50°C. At this point, the reactor pressure was 0.94 MPa. The gas inside the reactor was circulated through a condenser cooled to -40°C to -20°C and collected using a liquid nitrogen-cooled trap. 80.3 g of the collected material was obtained. Gas chromatography (GC) analysis confirmed the formation of trifluoromethanesulfonyl fluoride, yielding a purity of 98.9% and a yield of 88% (99% conversion, 89% selectivity).

Uses

Trifluoromethanesulfonyl fluoride is used as an intermediate in organic synthesis for the synthesis of sulfonic anhydrides, sulfonyl halides and their derivatives, and other substances.

Trifluoromethanesulfonyl fluoride Suppliers

Global Suppliers ( 41)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Aemon Chemical 0086-755-86198205 acinfo@aemonchem.com China 1928 57
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9656 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
VladaChem GmbH +49-7246-3082843 +86-18411632868 info@vladachem.de Germany 1854 58
Dayang Chem (Hangzhou) Co.,Ltd. +86-0571-88938639 17705817739 info@dycnchem.com China 52451 58
CONIER CHEM AND PHARMA LIMITED sales@conier.com China 49906 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 contact@trustwe.com China 5771 58
Pushan Industry (Shaanxi) Co., Ltd. 029-81310890 18165209495 2929288192@qq.com China 9949 58
PFC-MSF methanesulfonylfluoride,trifluoro- trifluoromethanesulfonyl fluoride CF4O2S trifluoro-methanesulfonylfluorid trifluoromethylsulfonylfluoride TRIFLUOROMETHANESULPHONYL FLUORIDE Trifluorometansulfonyl fluoride Trifluoromethanesulfonic acid fluoride Trifluoromethanesulphonyl fluoride 99% Trifluoromethanesulphonylfluoride99% Trifluoromethanesulfonyl fluoride 335-05-7 CF4O2S CF3SO2F