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2-Methyl-6-nitroaniline

2-Methyl-6-nitroaniline Structure
2-Methyl-6-nitroaniline structure
CAS No.
570-24-1
Chemical Name:
2-Methyl-6-nitroaniline
Synonyms
2-AMINO-3-NITROTOLUENE;6-NITRO-O-TOLUIDINE;3-NITRO-2-AMINOTOLUENE;2-Amino-3-nitro toulene;NSC 286;NSC 52218;-6-nitroaniL;6-Nitro-o-tol;LABOTEST-BB LTBB000621;6-Nitro-2-Methylaniline
CBNumber:
CB8457596
Molecular Formula:
C7H8N2O2
Molecular Weight:
152.15
MDL Number:
MFCD00007744
MOL File:
570-24-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-04 16:00:12
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2-Methyl-6-nitroaniline Properties

Melting point 93-96 °C (lit.)
Boiling point 124 °C / 1mmHg
Density 1.19 g/cm3
refractive index 1.6276 (estimate)
Flash point 110 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility <1mg/l
pka -0.44±0.25(Predicted)
form Crystalline Powder
color Brownish
Water Solubility <0.1 g/100 mL at 23 ºC
BRN 1868029
Henry's Law Constant 4.6×101 mol/(m3Pa) at 25℃, Abraham and Jr. (2019)
Cosmetics Ingredients Functions HAIR DYEING
InChI 1S/C7H8N2O2/c1-5-3-2-4-6(7(5)8)9(10)11/h2-4H,8H2,1H3
InChIKey FCMRHMPITHLLLA-UHFFFAOYSA-N
SMILES Cc1cccc(c1N)[N+]([O-])=O
CAS DataBase Reference 570-24-1(CAS DataBase Reference)
EWG's Food Scores 1-4
FDA UNII OUP165YKBC
NIST Chemistry Reference 2-Methyl-6-nitroaniline(570-24-1)
EPA Substance Registry System 2-Methyl-6-nitroaniline (570-24-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301+H311+H331-H373-H410
Precautionary statements  P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P314
PPE Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes  T,N,Xi
Risk Statements  23/24/25-33-51/53
Safety Statements  28-36/37-45-61-28A
RIDADR  UN 2660 6.1/PG 3
WGK Germany  3
F  10
Hazard Note  Toxic
HazardClass  IRRITANT
HazardClass  6.1
PackingGroup  Ⅲ
HS Code  29214300
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 2
STOT RE 2
REACH Registrations Inactive
Limited Quantities 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
3 0

2-Methyl-6-nitroaniline price More Price(69)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M59408 2-Methyl-6-nitroaniline 99% 570-24-1 10g $83 2026-04-30 Buy
Sigma-Aldrich M59408 2-Methyl-6-nitroaniline 99% 570-24-1 100g $674 2023-06-20 Buy
TCI Chemical N0467 2-Methyl-6-nitroaniline >99.0%(GC) 570-24-1 25g $187 2026-04-30 Buy
TCI Chemical N0467 2-Methyl-6-nitroaniline >99.0%(GC) 570-24-1 250g $661 2026-04-30 Buy
TRC TRC-M323560-5G 2-Methyl-6-nitroaniline 570-24-1 5g $65 2026-06-03 Buy
Product number Packaging Price Buy
M59408 10g $83 Buy
M59408 100g $674 Buy
N0467 25g $187 Buy
N0467 250g $661 Buy
TRC-M323560-5G 5g $65 Buy

2-Methyl-6-nitroaniline Chemical Properties, Uses, Production

Uses

2-Methyl-6-nitroaniline is a compound useful in organic synthesis. Dyes and metabolites, Environmental Testing.

Chemical Properties

Redish-Brown Solid

Uses

2-Methyl-6-nitroaniline (cas# 570-24-1) is a compound useful in organic synthesis. Dyes and metabolites, Environmental Testing

General Description

Orange-yellow prisms or brown granular powder.

Air & Water Reactions

2-Methyl-6-nitroaniline is sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

2-Methyl-6-nitroaniline is incompatible with acids, acid chlorides, acid anhydrides, chloroformates, and strong oxidizers.

Fire Hazard

Flash point data for 2-Methyl-6-nitroaniline are not available, but 2-Methyl-6-nitroaniline is probably combustible.

Synthesis

2-METHYLACETANILIDE

120-66-1

2-Methyl-6-nitroaniline

570-24-1

The general procedure for the synthesis of 2-methyl-6-nitroaniline from 2-methylacetanilide was carried out as follows: the modified Howard method [27] was used. Toluidine (1a or 1b; 53.5 mL, 0.5 mol) was slowly added to acetic anhydride (325 mL) in batches while maintaining constant stirring. The reaction solution was cooled to 12-13 °C in an ice-salt bath. Subsequently, 70% nitric acid (63 mL) was slowly added dropwise to the reaction mixture at a rate that maintained the temperature at 10-12 °C with constant stirring. The dropwise addition process took 2.5 h to complete, after which the solution was poured into 1.5 L of ice water. The resulting acetamide (3a, or a mixture of 3b and 3c) precipitate (as a cream-colored solid) was collected on a Brinell's funnel, washed with four 250 mL portions of ice water, and partially dried by suction. The wetted acetamide (3a, or a mixture of 3b and 3c) was mixed with 70% sulfuric acid (100 mL) and stirred at reflux for 3 hours. The acetamide 3b was separated from the reaction mixture by steam distillation to give the hydrolysis product of 2-methyl-6-nitroaniline (4b). After the distiller was cooled, the isolated bright orange needle-like crystals 4b were collected on a Brinell funnel and dried in a vacuum desiccator. If acetamide 3a was hydrolyzed, the warm reaction mixture was diluted with 350 mL of water and alkalized with 10% aqueous sodium hydroxide. After cooling to room temperature, 4-methyl-2-nitroaniline (4a) precipitated as a brown powder, which was separated by vacuum filtration, washed with three parts of 200 mL of water, and dried in a vacuum desiccator. The yields of compounds 4a and 4b were 53.6% (40.73 g) and 52.3% (39.78 g), respectively.

References

[1] Bulletin des Societes Chimiques Belges, 1969, vol. 78, p. 571 - 582
[2] Chemistry Letters, 1989, p. 1849 - 1852
[3] Journal of Medicinal Chemistry, 2012, vol. 55, # 13, p. 6047 - 6060
[4] Polyhedron, 2016, vol. 105, p. 137 - 149

2-Methyl-6-nitroaniline synthesis

98-33-9
570-24-1
Synthesis of 2-Methyl-6-nitroaniline from 2-Aminotoluene-5-sulfonic acid

2-Methyl-6-nitroaniline Preparation Products And Raw materials

Raw materials

2-Methylacetanilide 2-Azido-3-nitrotoluene o-Oxalotoluidide 2-Aminotoluene-5-sulfonic acid Sulfuric acid
2-Methyl-4-nitroacetanilide Acetic anhydride N-(2-Methyl-6-nitro-phenyl)-acetamide Nitric acid 4-Methyl-2-nitroaniline

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Preparation Products

2,1,3-Benzothiadiazole-4-carboxylic acid 2,1,3-Benzothiadiazol-4-ylmethanol,97% 4-(Bromomethyl)-2,1,3-benzothiadiazole 7-Nitroindazole 1H-Indazol-7-amine
2,1,3-Benzothiadiazole-4-carbaldehyde 2-Bromo-3-nitrotoluene 2,3-Dinitrobenzoic acid 4-methyl-1H-benzotriazole 3-Amino-2-bromo-benzoic acid methyl ester
4-broMo-3-Methylbenzene-1,2-diaMine 5-Bromo-7-nitro-1H-indazole Methyl 2-bromo-3-nitrobenzoate

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2-Methyl-6-nitroaniline Suppliers

Global Suppliers ( 437)
Supplier Tel Email Country ProdList Advantage
Jiangsu 01 Industrial Co., Ltd 0523-87653988 15105181882 519181683@qq.com China 131 58
Beijing Bainiannuan Sci.&Tec. Co., Ltd 13240490036 marymeng@bdnchem.com China 35 58
Greenspring Biotechnology (Jiangsu) Co., Ltd. 0523-87726088 13705266400 524535288@qq.com China 117 58
Nanbu County Chengxin Technology Co., Ltd. 0838-5675166 15883665058 nbcxkj@126.com China 956 55
Wuhan EnTai Technology Development Co,.Ltd 86-27-82330560 2536851935@qq.com China 346 69
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
Supplier Advantage
Jiangsu 01 Industrial Co., Ltd 58
Beijing Bainiannuan Sci.&Tec. Co., Ltd 58
Greenspring Biotechnology (Jiangsu) Co., Ltd. 58
Nanbu County Chengxin Technology Co., Ltd. 55
Wuhan EnTai Technology Development Co,.Ltd 69
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56

View Latest Price from 2-Methyl-6-nitroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methyl-6-nitroaniline pictures 2026-09-17 2-Methyl-6-nitroaniline
570-24-1
 $83.72 25Kg/Drum 99.0%HPLC 10tons/month Asia Chem I and E (Jiangsu) Co Ltd
2-Methyl-6-nitroaniline pictures 2026-05-28 2-Methyl-6-nitroaniline
570-24-1
 $10.70 10kg 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
2-Methyl-6-nitroaniline pictures 2025-05-23 2-Methyl-6-nitroaniline
570-24-1
 $10.00 1kg 99% 20 ton Hebei Zhuanglai Chemical Trading Co Ltd

2-Methyl-6-nitroaniline Spectrum

2-Methyl-6-nitroaniline(570-24-1)MS2-Methyl-6-nitroaniline(570-24-1)1HNMR2-Methyl-6-nitroaniline(570-24-1)13CNMR2-Methyl-6-nitroaniline(570-24-1)IR12-Methyl-6-nitroaniline(570-24-1)IR22-Methyl-6-nitroaniline(570-24-1)Raman

570-24-1 (2-Methyl-6-nitroaniline) Related Search:

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Thiophanate-methyl Tris(hydroxymethyl)aminomethane Aminoethoxyvinyl glycine hydrochloride

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6-NITRO-O-TOLUIDINE 2-METHYL-6-NITROBENZENAMINE 2-METHYL-6-NITROANILINE 2-NITRO-6-METHYLANILINE 2-AMINO-1-METHYL-3-NITROBENZENE Benzenamine, 2-methyl-6-nitro- LABOTEST-BB LTBB000621 2-Amino-3-nitrotoluene~6-Nitro-o-toluidine 2-Methyl-6-nitroaniline,(2-Amino-3-nitrotoluene 6-Nitro-2-Methylaniline 6-Nitro-o-tol Methylnitroaniline, 99% 2-Methyl-6-nitro-phenylamine 2-METHYL-6-NITROANILINE OEKANAL, 250 MG 1-AMINO-2-METHYL-6-NITROBENZENE 6-NITRO-ORTHO-TOLUIDINE 6-Nitro-o-toluidine (NH2=1) 2-METHYL-6-NITROANILINE 99% 2-Amino-3-nitrotoluene (2-Methyl-6-nitroaniline) 2-AMINO-3-NITROTOLUENE 99% 2-Methyl-6-nitroaniline,99% 2-Methyl-6-nitroaniline ,98% 2-Methyl-6-nitroaniline, 99% 25GR 1-Nitro-2-aMino-3-Methylbenzene NSC 286 NSC 52218 2-Amino-1-methyl-3-nitrobenzene 3-Nitro-2-aminotoluene 6-Nitro-o-toluidine 2-Amino-3-methylnitrobenzene 6-Nitro-o-toluidine(2-Methyl-6-nitroaniline) 2-Methyl-6-nitroaniline> -6-nitroaniL high quality 2-Methyl-6-nitroaniline 1 2-Methyl-6-nitroaniline ISO 9001：2015 REACH 2-Amino-3-nitro toulene 3-Nitro 2-Amino Toluene (2-Methyl 6-Nitro Aniline) C10207400 2-Amino-3-nitrotoluene 2-Amino-3-nitrotoluene, 98% 2-methyl-6-nitroaniline, 99%min 2-AMINO-3-NITROTOLUENE 3-NITRO-2-AMINOTOLUENE 570-24-1 NO2C6H3NH2CH3 Nitrogen Compounds Organic Building Blocks C7 Building Blocks Amines Phenyls & Phenyl-Het Building Blocks C7 Chemical Synthesis Nitrogen Compounds Organic Building Blocks Pharmaceutical intermediates amine| nitro-compound Miscellaneous Reagents Aromatics Compounds Aromatics