Eltoprazine Dihydrochloride
- CAS No.
- 143485-51-2
- Chemical Name:
- Eltoprazine Dihydrochloride
- Synonyms
- Eltoprazine 2HCl;Eltoprazine Dihydrochloride;Eltoprazine dihydrochloride, 10 mM in DMSO;1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine Dihydrochloride
- CBNumber:
- CB84673552
- Molecular Formula:
- C12H17ClN2O2
- Molecular Weight:
- 256.73
- MDL Number:
- MFCD32062904
- MOL File:
- 143485-51-2.mol
Eltoprazine Dihydrochloride price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | E1357 | Eltoprazine Dihydrochloride | 143485-51-2 | 10MG | $151 | 2024-03-01 | Buy |
| TCI Chemical | E1357 | Eltoprazine Dihydrochloride | 143485-51-2 | 50MG | $539 | 2024-03-01 | Buy |
| Chem-Impex | 37867 | Eltoprazinedihydrochloride,≥98%(HPLC) ≥98%(HPLC) | 143485-51-2 | 50MG | $666.27 | 2021-12-16 | Buy |
| Chem-Impex | 37867 | Eltoprazinedihydrochloride,98%(HPLC) 98%(HPLC) | 143485-51-2 | 10MG | $164.64 | 2021-12-16 | Buy |
Eltoprazine Dihydrochloride Chemical Properties,Uses,Production
Uses
Eltoprazine (DU 28853) dihydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine dihydrochloride shows antiaggressive and anxiogenic effects[1][2].
in vivo
Rats are chronically treated with Mianserin (10 mg/kg i.p.) or Eltoprazine (1 mg/kg i.p.) and are tested in the elevated plus-maze test for anxiety. Mianserin and Eltoprazine display opposite effects in the elevated plus-maze: Mianserin induces anxiolytic-like effects, while Eltoprazine shows anxiogenic-like ones[2].
References
[1] Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites in the rat brain: an autoradiographic study. Eur J Pharmacol. 1990 Feb 20;177(1-2):55-66. DOI:10.1016/0014-2999(90)90549-l
[2] Rocha B, et al. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262(1-2):125-31. DOI:10.1016/0014-2999(94)90035-3
Eltoprazine Dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Eltoprazine Dihydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32277 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38664 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7249 | 62 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28387 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23671 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23653 | 75 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| TCI Chemicals | 021-67121386, 800-988-0390 | Sales-CN@TCIchemicals.com | China | 5391 | 58 |
View Lastest Price from Eltoprazine Dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-22 | Eltoprazine dihydrochloride
143485-51-2
|
US $48.00-127.00 / mg | 99.94% | 10g | TargetMol Chemicals Inc. |
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- Eltoprazine dihydrochloride
143485-51-2
- US $48.00-127.00 / mg
- 99.94%
- TargetMol Chemicals Inc.