Eltoprazine Dihydrochloride
- CAS No.
- 143485-51-2
- Chemical Name:
- Eltoprazine Dihydrochloride
- Synonyms
- Eltoprazine 2HCl;Eltoprazine Dihydrochloride;Eltoprazine dihydrochloride, 10 mM in DMSO;1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine Dihydrochloride
- CBNumber:
- CB84673552
- Molecular Formula:
- C12H17ClN2O2
- Molecular Weight:
- 256.73
- MDL Number:
- MFCD32062904
- MOL File:
- 143485-51-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Eltoprazine Dihydrochloride price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | E1357 | Eltoprazine Dihydrochloride | 143485-51-2 | 10MG | $107 | 2026-04-30 | Buy |
| TCI Chemical | E1357 | Eltoprazine Dihydrochloride | 143485-51-2 | 50MG | $381 | 2026-04-30 | Buy |
| Biosynth | TFA48551 | Eltoprazine dihydrochloride | 143485-51-2 | 100mg | $1134 | 2026-06-05 | Buy |
| Chem-Impex | 37867 | Eltoprazine dihydrochloride ≥98%(HPLC) | 143485-51-2 | 10MG | $204.31 | 2026-05-19 | Buy |
| Chem-Impex | 37867 | Eltoprazine dihydrochloride ≥98%(HPLC) | 143485-51-2 | 50MG | $767.25 | 2026-05-19 | Buy |
Eltoprazine Dihydrochloride Chemical Properties,Uses,Production
Uses
Eltoprazine (DU 28853) dihydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine dihydrochloride shows antiaggressive and anxiogenic effects[1][2].
in vivo
Rats are chronically treated with Mianserin (10 mg/kg i.p.) or Eltoprazine (1 mg/kg i.p.) and are tested in the elevated plus-maze test for anxiety. Mianserin and Eltoprazine display opposite effects in the elevated plus-maze: Mianserin induces anxiolytic-like effects, while Eltoprazine shows anxiogenic-like ones[2].
References
[1] Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites in the rat brain: an autoradiographic study. Eur J Pharmacol. 1990 Feb 20;177(1-2):55-66. DOI:10.1016/0014-2999(90)90549-l
[2] Rocha B, et al. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262(1-2):125-31. DOI:10.1016/0014-2999(94)90035-3
Eltoprazine Dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Eltoprazine Dihydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| TCI Chemicals | 021-67121386, 800-988-0390 | Sales-CN@TCIchemicals.com | China | 5389 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6288 | 58 |
| CHG Opto-Electronic Corporation Limited | 2537653158 16621191650 | 2537653158@qq.com | China | 7135 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
View Lastest Price from Eltoprazine Dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Eltoprazine dihydrochloride
143485-51-2
|
$30.00-76.00 | 99.94% | 10g | TargetMol Chemicals Inc. |
-
- Eltoprazine dihydrochloride
143485-51-2
- $30.00-76.00
- 99.94%
- TargetMol Chemicals Inc.
