N-Isopropyl-N'-phenyl-1,4-phenylenediamine
- CAS No.
- 101-72-4
- Chemical Name:
- N-Isopropyl-N'-phenyl-1,4-phenylenediamine
- Synonyms
- IPPD;4010na;Diafen FP;N-isopropyl-N'-phenyl-p-phenylenediamine;4010 NA;Antioxidant IPPD;N-isopropyl-N`-phenylenediamine;n-isopropyl-n-phenyl-4-phenylenediamine;S-IP;GIGS
- CBNumber:
- CB8475891
- Molecular Formula:
- C15H18N2
- Molecular Weight:
- 226.32
- MDL Number:
- MFCD00026348
- MOL File:
- 101-72-4.mol
- MSDS File:
- SDS
| Melting point | 72-76°C |
|---|---|
| Boiling point | 161°C |
| Density | 1,17 g/cm3 |
| vapor pressure | 0.007Pa at 20℃ |
| refractive index | 1.5000 (estimate) |
| Flash point | 161°C/1mm |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), DMSO (Slightly, Sonicated) |
| form | Solid |
| pka | 6.76±0.32(Predicted) |
| color | Grey to Very Dark Grey |
| biological source | rabbit |
| Water Solubility | <0.1 g/100 mL at 18 ºC |
| Sensitive | Air Sensitive |
| Henry's Law Constant | 7.0×103 mol/(m3Pa) at 25℃, HSDB (2015) |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| LogP | 2.77 at 20℃ |
| CAS DataBase Reference | 101-72-4(CAS DataBase Reference) |
| Indirect Additives used in Food Contact Substances | N-ISOPROPYL-N'-PHENYL-P-PHENYLENEDIAMINE |
| FDA 21 CFR | 177.2600 |
| EWG's Food Scores | 2 |
| FDA UNII | 0M7PSL4100 |
| NIST Chemistry Reference | P-phenylenediamine, n-isopropyl-n'-phenyl-(101-72-4) |
| EPA Substance Registry System | N-Isopropyl-N'-phenyl-p-phenylenediamine (101-72-4) |
| UNSPSC Code | 12352203 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317-H400-H410 | |||||||||
| Precautionary statements | P262-P273-P280g-P501a | |||||||||
| Hazard Codes | Xi,N,Xn | |||||||||
| Risk Statements | 36/37/38-50/53-43-22 | |||||||||
| Safety Statements | 26-36-61-60-37-24 | |||||||||
| RIDADR | 3077 | |||||||||
| RTECS | ST2650000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29215900 | |||||||||
| Hazardous Substances Data | 101-72-4(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 oral in rat: 720mg/kg | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
N-Isopropyl-N'-phenyl-1,4-phenylenediamine price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4503330 | Anti-DARPP-32, N-Terminal antibody produced in rabbit affinity isolated antibody | 101-72-4 | 100μG | $560 | 2026-04-30 | Buy |
| Sigma-Aldrich | S362956 | N-ISOPROPYL-N'-PHENYL-1,4-PHENYLENEDIAMINE Aldrich | 101-72-4 | 1g | $172 | 2023-06-20 | Buy |
| TCI Chemical | P0327 | 4-Isopropylaminodiphenylamine >98.0%(HPLC)(T) | 101-72-4 | 25g | $19 | 2026-04-30 | Buy |
| TCI Chemical | P0327 | 4-Isopropylaminodiphenylamine >98.0%(HPLC)(T) | 101-72-4 | 500g | $83 | 2026-04-30 | Buy |
| Cayman Chemical | 40725 | IPPD ≥95% | 101-72-4 | 100g | $30 | 2026-04-30 | Buy |
N-Isopropyl-N'-phenyl-1,4-phenylenediamine Chemical Properties, Uses, Production
Chemical Properties
dark grey to black solid
Uses
Protection of rubbers against oxidation, ozone, flex-cracking, and poisoning by copper and manganese.
Uses
N-Isopropyl-N-phenyl-4-phenyle-nediamine is used in protection of rubber against oxidation, ozone, flex-cracking, and poisoning by copper and manganese; antidegradant in natural rubber, styrene-butadiene, nitrile-butadiene, butadiene, and chloroprene rubber.
Uses
This rubber chemical is used as an antioxidant. The main occupational sources are tyres.
Definition
ChEBI: The N-substituted diamine that is 1,4-phenylenediamine substituted at one N with an isopropyl group and at the other with a phenyl group.
Synthesis Reference(s)
The Journal of Organic Chemistry, 29, p. 1265, 1964 DOI: 10.1021/jo01028a511
General Description
Dark gray to black flakes or brown-black small chip-like solid with an aromatic odor.
Air & Water Reactions
May be sensitive to heat, air, light and moisture during long term storage. Insoluble in water.
Reactivity Profile
N-Isopropyl-N'-phenyl-1,4-phenylenediamine reacts with oxidizing agents . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Fire Hazard
N-Isopropyl-N'-phenyl-1,4-phenylenediamine is combustible.
Flammability and Explosibility
Non flammable
Contact allergens
This rubber chemical is used as an antioxidant and antiozonant. The main occupational sources are tires.



N-Isopropyl-N'-phenyl-1,4-phenylenediamine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei long Kang Sheng Fine Chemical Co., Ltd. | 027-027-83850368 18140587623 | 3052398675@qq.com | China | 1000 | 58 |
| Wuxi Bingju Trading Co., Ltd. | 19850261379 | 931732006@qq.com | China | 78 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Record Tech (Shanghai) Co., LTD | 13761627472 | 183009664@qq.com | China | 659 | 62 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
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- Sep 30,2025
View Latest Price from N-Isopropyl-N'-phenyl-1,4-phenylenediamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-18 | N-Isopropyl-N'-phenyl-1,4-phenylenediamine
101-72-4
|
1kg/bag | ≥98% | 50 T/Month | Hebei Qujie Technology Co., Ltd. | ||
![]() |
2026-09-18 | N-Isopropyl-N'-phenyl-1,4-phenylenediamine
101-72-4
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
![]() |
2026-09-10 | N-Isopropyl-N-Phenyl-1,4-Phenylenediamin
101-72-4
|
96.69% | 10g | TargetMol Chemicals Inc. |
-

- N-Isopropyl-N'-phenyl-1,4-phenylenediamine
101-72-4
- $0.00
- ≥98%
- Hebei Qujie Technology Co., Ltd.
-

- N-Isopropyl-N'-phenyl-1,4-phenylenediamine
101-72-4
- 0.99
- RongNa Biotechnology Co.,Ltd
-

- N-Isopropyl-N-Phenyl-1,4-Phenylenediamin
101-72-4
- $0.00
- 96.69%
- TargetMol Chemicals Inc.






