2-(METHYLTHIO)-2-THIAZOLINE
- CAS No.
- 19975-56-5
- Chemical Name:
- 2-(METHYLTHIO)-2-THIAZOLINE
- Synonyms
- 2-(Methylthio)thiazoline;2-(METHYLTHIO)-2-THIAZOLINE;2-Thiazoline, 2-(methylthio)-;2-(Methylthio)-2-thiazoline>2-(METHYLMERCAPTO)-2-THIAZOLINE;2-(Methylsulfanyl)-1,3-thiazole;2-(Methylthio)-2-thiazoline 97%;2-(METHYLTHIO)-2-THIAZOLINE 99+%;4,5-dihydro-2-(methylthio)thiazole;2-(Methylthio)-4,5-dihydrothiazole
- CBNumber:
- CB8482787
- Molecular Formula:
- C4H7NS2
- Molecular Weight:
- 133.24
- MDL Number:
- MFCD00005312
- MOL File:
- 19975-56-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-(Methylthio)-2-thiazoline 97% | 250406 | 10g | $183 |
| 2-(Methylthio)-2-thiazoline >98.0%(GC) | M1262 | 5g | $35 |
| 2-(Methylthio)-2-thiazoline >98.0%(GC) | M1262 | 25g | $172 |
| 2-(Methylthio)-2-thiazoline ≥98%(GC) | 44155 | 5G | $56.48 |
| 2-(Methylthio)-2-thiazoline ≥98%(GC) | 44155 | 25G | $262.59 |
| Boiling point | 216-217 °C (lit.) |
|---|---|
| Density | 1.226 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 208 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | 4.74±0.10(Predicted) |
| color | Colorless to Light yellow |
| BRN | 106353 |
| InChI | 1S/C4H7NS2/c1-6-4-5-2-3-7-4/h2-3H2,1H3 |
| InChIKey | QFGRBBWYHIYNIB-UHFFFAOYSA-N |
| SMILES | CSC1=NCCS1 |
| FDA UNII | H7RAG4X25D |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves | |||||||||
| Safety Statements | 23-24/25 | |||||||||
| RIDADR | UN 3334 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-9-13 | |||||||||
| HS Code | 29341000 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
2-(METHYLTHIO)-2-THIAZOLINE price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 250406 | 2-(Methylthio)-2-thiazoline 97% | 19975-56-5 | 10g | $183 | 2026-04-30 | Buy |
| TCI Chemical | M1262 | 2-(Methylthio)-2-thiazoline >98.0%(GC) | 19975-56-5 | 5g | $35 | 2026-04-30 | Buy |
| TCI Chemical | M1262 | 2-(Methylthio)-2-thiazoline >98.0%(GC) | 19975-56-5 | 25g | $172 | 2026-04-30 | Buy |
| Chem-Impex | 44155 | 2-(Methylthio)-2-thiazoline ≥98%(GC) | 19975-56-5 | 5G | $56.48 | 2026-05-19 | Buy |
| Chem-Impex | 44155 | 2-(Methylthio)-2-thiazoline ≥98%(GC) | 19975-56-5 | 25G | $262.59 | 2026-05-19 | Buy |
2-(METHYLTHIO)-2-THIAZOLINE Chemical Properties,Uses,Production
Uses
thiazolidin e thione pharmaceutical intermediate
Uses
2-(Methylthio)-2-thiazoline has been used in the preparation of:
- novel tri- and tetracyclic hetero systems, via reaction with heteroaromatic 2-aminoesters
- 2-(2-chlorobenzylamino)-2-thiazoline
Synthesis
134469-06-0
74-88-4
19975-56-5
General procedure for the synthesis of 2-methylthio-2-thiazoline from thiazolidine-2-thione and iodomethane: Thiazolidine-2-thione (2 g, 0.0168 mol) was dissolved in acetonitrile (20 ml) and iodomethane (1.04 ml, 0.0168 mol) was added. The reaction mixture was heated to reflux for 3 hours and subsequently cooled to room temperature. The reaction mixture was filtered and the white solid obtained was collected. The solid was poured into saturated potassium carbonate solution (20 ml) to form an oil. The oily substance was extracted with dichloromethane and the organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give a colorless liquid product (1.4 g, 63% yield).
References
[1] Synthetic Communications, 2006, vol. 36, # 22, p. 3339 - 3343
[2] Patent: CN105481846, 2016, A. Location in patent: Paragraph 0006; 0007
[3] Journal of the American Chemical Society, 1958, vol. 80, p. 3335,3338
[4] Journal of Organic Chemistry, 1961, vol. 26, p. 85 - 88
[5] Helvetica Chimica Acta, 1978, vol. 61, p. 3143 - 3148
2-(METHYLTHIO)-2-THIAZOLINE Preparation Products And Raw materials
Raw materials
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Preparation Products
2-(METHYLTHIO)-2-THIAZOLINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
View Lastest Price from 2-(METHYLTHIO)-2-THIAZOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-12-24 | 2-(METHYLTHIO)-2-THIAZOLINE
19975-56-5
|
$1.00 | 1KG | 98%min | Career Henan Chemical Co |
-

- 2-(METHYLTHIO)-2-THIAZOLINE
19975-56-5
- $1.00
- 98%min
- Career Henan Chemical Co
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