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2-(METHYLTHIO)-2-THIAZOLINE

CAS No.
19975-56-5
Chemical Name:
2-(METHYLTHIO)-2-THIAZOLINE
Synonyms
2-(Methylthio)thiazoline;2-(METHYLTHIO)-2-THIAZOLINE;2-Thiazoline, 2-(methylthio)-;2-(Methylthio)-2-thiazoline>2-(METHYLMERCAPTO)-2-THIAZOLINE;2-(Methylsulfanyl)-1,3-thiazole;2-(Methylthio)-2-thiazoline 97%;2-(METHYLTHIO)-2-THIAZOLINE 99+%;4,5-dihydro-2-(methylthio)thiazole;2-(Methylthio)-4,5-dihydrothiazole
CBNumber:
CB8482787
Molecular Formula:
C4H7NS2
Molecular Weight:
133.24
MDL Number:
MFCD00005312
MOL File:
19975-56-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:16:24
Product description Number Pack Size Price
2-(Methylthio)-2-thiazoline 97% 250406 10g $183
2-(Methylthio)-2-thiazoline >98.0%(GC) M1262 5g $35
2-(Methylthio)-2-thiazoline >98.0%(GC) M1262 25g $172
2-(Methylthio)-2-thiazoline ≥98%(GC) 44155 5G $56.48
2-(Methylthio)-2-thiazoline ≥98%(GC) 44155 25G $262.59

2-(METHYLTHIO)-2-THIAZOLINE Properties

Boiling point 216-217 °C (lit.)
Density 1.226 g/mL at 25 °C (lit.)
refractive index n20/D 1.592(lit.)
Flash point 208 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form clear liquid
pka 4.74±0.10(Predicted)
color Colorless to Light yellow
BRN 106353
InChI 1S/C4H7NS2/c1-6-4-5-2-3-7-4/h2-3H2,1H3
InChIKey QFGRBBWYHIYNIB-UHFFFAOYSA-N
SMILES CSC1=NCCS1
FDA UNII H7RAG4X25D
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves
Safety Statements  23-24/25
RIDADR  UN 3334
WGK Germany  3
8-9-13
HS Code  29341000
Storage Class 10 - Combustible liquids
NFPA 704
1
2 0

2-(METHYLTHIO)-2-THIAZOLINE price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 250406 2-(Methylthio)-2-thiazoline 97% 19975-56-5 10g $183 2026-04-30 Buy
TCI Chemical M1262 2-(Methylthio)-2-thiazoline >98.0%(GC) 19975-56-5 5g $35 2026-04-30 Buy
TCI Chemical M1262 2-(Methylthio)-2-thiazoline >98.0%(GC) 19975-56-5 25g $172 2026-04-30 Buy
Chem-Impex 44155 2-(Methylthio)-2-thiazoline ≥98%(GC) 19975-56-5 5G $56.48 2026-05-19 Buy
Chem-Impex 44155 2-(Methylthio)-2-thiazoline ≥98%(GC) 19975-56-5 25G $262.59 2026-05-19 Buy
Product number Packaging Price Buy
250406 10g $183 Buy
M1262 5g $35 Buy
M1262 25g $172 Buy
44155 5G $56.48 Buy
44155 25G $262.59 Buy

2-(METHYLTHIO)-2-THIAZOLINE Chemical Properties,Uses,Production

Uses

thiazolidin e thione pharmaceutical intermediate

Uses

2-(Methylthio)-2-thiazoline has been used in the preparation of:

  • novel tri- and tetracyclic hetero systems, via reaction with heteroaromatic 2-aminoesters
  • 2-(2-chlorobenzylamino)-2-thiazoline

Synthesis

2-Thiazolethiol, 4,5-dihydro-

134469-06-0

Iodomethane

74-88-4

2-(METHYLTHIO)-2-THIAZOLINE

19975-56-5

General procedure for the synthesis of 2-methylthio-2-thiazoline from thiazolidine-2-thione and iodomethane: Thiazolidine-2-thione (2 g, 0.0168 mol) was dissolved in acetonitrile (20 ml) and iodomethane (1.04 ml, 0.0168 mol) was added. The reaction mixture was heated to reflux for 3 hours and subsequently cooled to room temperature. The reaction mixture was filtered and the white solid obtained was collected. The solid was poured into saturated potassium carbonate solution (20 ml) to form an oil. The oily substance was extracted with dichloromethane and the organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give a colorless liquid product (1.4 g, 63% yield).

References

[1] Synthetic Communications, 2006, vol. 36, # 22, p. 3339 - 3343
[2] Patent: CN105481846, 2016, A. Location in patent: Paragraph 0006; 0007
[3] Journal of the American Chemical Society, 1958, vol. 80, p. 3335,3338
[4] Journal of Organic Chemistry, 1961, vol. 26, p. 85 - 88
[5] Helvetica Chimica Acta, 1978, vol. 61, p. 3143 - 3148

134469-06-0
74-88-4
19975-56-5
Synthesis of 2-(METHYLTHIO)-2-THIAZOLINE from 2-Thiazolethiol, 4,5-dihydro- and Iodomethane

2-(METHYLTHIO)-2-THIAZOLINE Suppliers

Global( 113)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Finetech Industry Limited
+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9539 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471; sales@sarms4muscle.com China 10473 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 24597 58

View Lastest Price from 2-(METHYLTHIO)-2-THIAZOLINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(METHYLTHIO)-2-THIAZOLINE pictures 2019-12-24 2-(METHYLTHIO)-2-THIAZOLINE
19975-56-5
$1.00 1KG 98%min Career Henan Chemical Co
2-methylsulfanyl-4,5-dihydrothiazoline 2-Methylsulfanyl-4,5-dihydro-thiazole 2-(Methylsulfanyl)-4,5-dihydro-1,3-thiazole 2-(Methylthio)thiazoline 2-Thiazoline, 2-(methylthio)- 2-(METHYLMERCAPTO)-2-THIAZOLINE 2-(METHYLTHIO)-2-THIAZOLINE 2-(Methylthio)-4,5-dihydro-1,3-thiazole 2-(Methylthio)-4,5-dihydrothiazole 2-(Methylsulfanyl)-1,3-thiazole 4,5-dihydro-2-(methylthio)thiazole 2-Methylsulfanyl-4,5-dihydro-3H-1l4-thiazole Thiazole, 4,5-dihydro-2-(Methylthio)- 2-(METHYLTHIO)-2-THIAZOLINE 99+% 2-(Methylthio)-2-thiazoline 97% 2-(Methylthio)-2-thiazoline> 19975-56-5 C4H7NS2 Building Blocks Thiazolines/Thiazolidines Heterocyclic Building Blocks chemical additive pharmaceutical intermediate Building Blocks Chemical Synthesis Heterocyclic Building Blocks Thiazolines/Thiazolidines