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MAC glucuronide α-hydroxy lactone-linked SN-38

MAC glucuronide α-hydroxy lactone-linked SN-38 Structure
MAC glucuronide α-hydroxy lactone-linked SN-38 structure
CAS No.
2246380-70-9
Chemical Name:
MAC glucuronide α-hydroxy lactone-linked SN-38
Synonyms
MAC glucuronide α-hydroxy lactone-linked SN-38;MAC glucuronide α-hydroxy lactone-linked SN-38
CBNumber:
CB85540538
Molecular Formula:
C50H54N6O20S
Molecular Weight:
1091.06
MDL Number:
MFCD32202363
MOL File:
2246380-70-9.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:57
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MAC glucuronide α-hydroxy lactone-linked SN-38 Properties

Boiling point 1399.8±65.0 °C(Predicted)
Density 1.63±0.1 g/cm3(Predicted)
pka 2.77±0.70(Predicted)
form Solid
color Light yellow to green yellow

MAC glucuronide α-hydroxy lactone-linked SN-38 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Arctom HY-128942 MAC glucuronide α-hydroxy lactone-linked SN-38 2246380-70-9 1mg $380 2026-05-26 Buy
Arctom HY-128942 MAC glucuronide α-hydroxy lactone-linked SN-38 2246380-70-9 5mg $1140 2026-05-26 Buy
Arctom HY-128942 MAC glucuronide α-hydroxy lactone-linked SN-38 2246380-70-9 10mg $2033 2026-05-26 Buy
Arctom HY-128942 MAC glucuronide α-hydroxy lactone-linked SN-38 2246380-70-9 25mg $4454 2026-05-26 Buy
Product number Packaging Price Buy
HY-128942 1mg $380 Buy
HY-128942 5mg $1140 Buy
HY-128942 10mg $2033 Buy
HY-128942 25mg $4454 Buy

MAC glucuronide α-hydroxy lactone-linked SN-38 Chemical Properties, Uses, Production

Uses

MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide α-hydroxy lactone-linked SN-38 agent linker. MAC glucuronide α-hydroxy lactone-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively[1].

IC 50

Camptothecins

References

[1] Lau UY, et al. Lactone Stabilization is Not a Necessary Feature for Antibody Conjugates of Camptothecins. Mol Pharm. 2018 Sep 4;15(9):4063-4072. DOI:10.1021/acs.molpharmaceut.8b00477

MAC glucuronide α-hydroxy lactone-linked SN-38 Preparation Products And Raw materials

Raw materials

Preparation Products

MAC glucuronide α-hydroxy lactone-linked SN-38 Suppliers

Global Suppliers ( 8)
Supplier Tel Email Country ProdList Advantage
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd. 0755-23251735 13302967066 sales@geneseqtools.com China 1466 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Nanchang Tianzhen Biotechnology Co., Ltd 13758194781 13173652190 522013271@qq.com China 2447 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai Kaisen Biotechnology Co., Ltd 17558870519 sales02@chemsoon.com China 1939 58
YantaiBio 13758194781; 13758194781 764619768@qq.com China 1773 58
Supplier Advantage
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd. 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nanchang Tianzhen Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Kaisen Biotechnology Co., Ltd 58
YantaiBio 58

2246380-70-9 (MAC glucuronide α-hydroxy lactone-linked SN-38) Related Search:

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MAC glucuronide α-hydroxy lactone-linked SN-38 MAC glucuronide α-hydroxy lactone-linked SN-38 2246380-70-9 ADC LINKER