CHGA antibody
- CAS No.
- Chemical Name:
- CHGA antibody
- Synonyms
- CHGA antibody;Rabbit Polyclonal CHGA Antibody
- CBNumber:
- CB85617214
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
CHGA antibody Chemical Properties, Uses, Production
Source
Rabbit
Applications
CHGA antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Recommended dilution range for Western blot is 1:500 ~ 1:1,000 and immunohistochemistry analysis is 1:100~200. Recommended starti
Reactivity
Human
Immunogen
Anti-human CHGA mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CHGA amino acids 19-131 purified from E. coli.
Background
Chromgranin-A is part of the neuroendocrine secretory protein family. CHGA is located in secretory vesicles of neurons and endocrine cells. Chromgranin-A is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. Chromgranin-A has numerous biological activities on some tissues and organs and exerts a large spectrum of homeostatic actions, including antifungal and antimicrobial effect, modulation of cell adhesion, and inhibition of parathyroid hormone secretion.
References
[1] Machado, J.D. et al. (2010) Cell Mol Neurobiol 30, 1181-7.
[2] Dominguez, N. et al. (2018) J Neurochem 144, 241-54.
[3] Weisbrod, A.B. et al. (2013) Horm Cancer 4, 165-75.
[4] Annaratone, L. et al. (2014) Endocr Pathol 25, 219-28.
[5] Ardill, J.E. and Erikkson, B. (2003) Endocr Relat Cancer 10, 459-62.
[6] Welin, S. et al. (2009) Neuroendocrinology 89, 302-7.
CHGA antibody Preparation Products And Raw materials
Raw materials
Preparation Products
CHGA antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Serenity BioSolutions Co., Ltd. | 027-19371278702 18008634902 | 19384116026@163.com | China | 3008 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Serenity BioSolutions Co., Ltd. | 58 |
