SRI-29329
- CAS No.
- 2086809-58-5
- Chemical Name:
- SRI-29329
- Synonyms
- SRI-29329;SRI-29329, 10 mM in DMSO;Cyclin dependent kinase,inhibit,SRI29329,SRI-29329,Inhibitor,SRI 29329,CDK;N2-((1S,2S)-2-Aminocyclohexyl)-N6-(3-chlorophenyl)-9-isopropyl-9H-purine-2,6-diamine;9H-Purine-2,6-diamine, N2-[(1S,2S)-2-aminocyclohexyl]-N6-(3-chlorophenyl)-9-(1-methylethyl)-
- CBNumber:
- CB85867459
- Molecular Formula:
- C20H26ClN7
- Molecular Weight:
- 399.92
- MDL Number:
- MFCD32899878
- MOL File:
- 2086809-58-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
SRI-29329 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | LID80958 | N2-((1S,2S)-2-Aminocyclohexyl)-N6-(3-chlorophenyl)-9-isopropyl-9H-purine-2,6-diamine | 2086809-58-5 | 25mg | $1091.5 | 2026-06-04 | Buy |
| Biosynth | LID80958 | N2-((1S,2S)-2-Aminocyclohexyl)-N6-(3-chlorophenyl)-9-isopropyl-9H-purine-2,6-diamine | 2086809-58-5 | 50mg | $1518.5 | 2026-06-04 | Buy |
| ChemScene | CS-0083792 | SRI-29329 99.14% | 2086809-58-5 | 5mg | $271 | 2026-06-04 | Buy |
| ChemScene | CS-0083792 | SRI-29329 99.14% | 2086809-58-5 | 10mg | $433 | 2026-06-04 | Buy |
| ChemScene | CS-0083792 | SRI-29329 99.14% | 2086809-58-5 | 25mg | $812 | 2026-06-04 | Buy |
SRI-29329 Chemical Properties, Uses, Production
Uses
SRI-29329 is a specific CLK inhibitor, with IC50 values of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively[1].
Biological Activity
SRI-29329 is a specific CLK inhibitor, with IC50 values of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively[1]. SRI-29329 (compound 8) shows some modest (~5 fold) selectivity for CLK2 over CLK1 and CLK4 without significant CDK1,4,6 activity[1].
References
[1]. Yihui Shi, et al. A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore. Bioorg Med Chem Lett. 2017 Feb 1;27(3):406-412.
SRI-29329 Preparation Products And Raw materials
Raw materials
Preparation Products
SRI-29329 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2994 | 55 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9778 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Shanghai?Medlife?Pharm-Tech?Co.,?Ltd | 4000862158 18117107507 | vip@med-life.cn | China | 4999 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd | 025-5885952 15955137747 | sales@aikonchem.com | China | 8012 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
