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ChemicalBook >> CAS DataBase List >>3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)

3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)

3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) Structure
3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) structure
CAS No.
4322-58-1
Chemical Name:
3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)
Synonyms
-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one);3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one);3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one);3,3′-[(2-chlorophenyl)methylene]bis[4-hydroxy-2H-1-benzopyran-2-one;2H-1-Benzopyran-2-one, 3,3'-[(2-chlorophenyl)methylene]bis[4-hydroxy-
CBNumber:
CB86197889
Molecular Formula:
C25H15ClO6
Molecular Weight:
446.84
MDL Number:
MOL File:
4322-58-1.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) Properties

Melting point 198-199 °C
Boiling point 703.3±60.0 °C(Predicted)
Density 1.575±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:7): 0.14 mg/ml
form A crystalline solid
pka 4.20±1.00(Predicted)

3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29864 3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) ≥98% 4322-58-1 1mg $41 2026-04-30 Buy
Cayman Chemical 29864 3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) ≥98% 4322-58-1 5mg $157 2026-04-30 Buy
Cayman Chemical 29864 3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) ≥98% 4322-58-1 10mg $293 2026-04-30 Buy
Cayman Chemical 29864 3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) ≥98% 4322-58-1 25mg $680 2026-04-30 Buy
ChemScene CS-0299947 Urease-IN-17 98% 4322-58-1 1mg $154 2026-06-04 Buy
Product number Packaging Price Buy
29864 1mg $41 Buy
29864 5mg $157 Buy
29864 10mg $293 Buy
29864 25mg $680 Buy
CS-0299947 1mg $154 Buy

3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) Chemical Properties, Uses, Production

Description

3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) is a non-nucleotide inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; Ki = 50 μM).1,2 It also inhibits urease (IC50 = 84.53 μM for the Jack bean enzyme).3

Uses

Urease-IN-17 (9) is a urease inhibitor, with an IC50 of 84 μM[1].

References

1. Choudhary, M.I., Fatima, N., Khan, K.M., et al. New biscoumarin derivatives-cytotoxicity and enzyme inhibitory activities Bioorg. Med. Chem. 14(23),8066-8072(2006).
2. Onyedibe, K.I., Wang, M., and Sintim, H.O. ENPP1, an old enzyme with new functions, and small molecule inhibitors - A STING in the tale of ENPP1 Molecules 24(22),E4192(2019).
3. Khan, K.M., Iqbal, S., Lodhi, M.A., et al. Biscoumarin: New class of urease inhibitors; economical synthesis and activity Bioorg. Med. Chem. 12(8),1963-1968(2004).

3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) Preparation Products And Raw materials

Raw materials

Preparation Products

3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) Suppliers

Global Suppliers ( 10)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from 3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) pictures 2026-04-20 3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)
4322-58-1
 $133.00-963.00 10g TargetMol Chemicals Inc.

4322-58-1 (3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)) Related Search:

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3,3''-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) -((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) 2H-1-Benzopyran-2-one, 3,3'-[(2-chlorophenyl)methylene]bis[4-hydroxy- 3,3′-[(2-chlorophenyl)methylene]bis[4-hydroxy-2H-1-benzopyran-2-one 3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) 4322-58-1