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4-Hydroxy carbazole

CAS No.
52602-39-8
Chemical Name:
4-Hydroxy carbazole
Synonyms
9H-CARBAZOL-4-OL;4-Hydroxycarbazole;SKF 106023;4-Carbazolol;qiangjibianzuo;9H-CARBAZOLE-4-OL;9-H-CARBAZOL-4-OI;p-HydroxycarBazole;4-hidroxy carbazol;4-Hydroxycarbazole>
CBNumber:
CB8663261
Molecular Formula:
C12H9NO
Molecular Weight:
183.21
MDL Number:
MFCD02178385
MOL File:
52602-39-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:43:49

4-Hydroxy carbazole Properties

Melting point 169-173 °C (lit.)
Boiling point 431.4±18.0 °C(Predicted)
Density 1.362±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightlty), Methanol (Slightly)
pka 9.87±0.30(Predicted)
form Powder
color Tan to cacao
InChI InChI=1S/C12H9NO/c14-11-7-3-6-10-12(11)8-4-1-2-5-9(8)13-10/h1-7,13-14H
InChIKey UEOHATPGKDSULR-UHFFFAOYSA-N
SMILES N1C2=C(C=CC=C2)C2=C1C=CC=C2O
CAS DataBase Reference 52602-39-8(CAS DataBase Reference)
FDA UNII 3D95E7727V
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
HS Code  29339900
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
REACH Registrations Active
NFPA 704
0
2 0

4-Hydroxy carbazole price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 543896 4-Hydroxycarbazole 95% 52602-39-8 5g $84.6 2026-04-30 Buy
TCI Chemical H1014 4-Hydroxycarbazole >98.0%(HPLC) 52602-39-8 1g $20 2026-04-30 Buy
TCI Chemical H1014 4-Hydroxycarbazole >98.0%(HPLC) 52602-39-8 5g $34 2026-04-30 Buy
Biosynth FH23935 4-Hydroxy carbazole 52602-39-8 250g $150 2026-06-04 Buy
Biosynth FH23935 4-Hydroxy carbazole 52602-39-8 100g $150 2026-06-04 Buy
Product number Packaging Price Buy
543896 5g $84.6 Buy
H1014 1g $20 Buy
H1014 5g $34 Buy
FH23935 250g $150 Buy
FH23935 100g $150 Buy

4-Hydroxy carbazole Chemical Properties, Uses, Production

Chemical Properties

Light-Yellow Solid

Uses

4-Hydroxy Carbazole (cas# 52602-39-8) is a compound useful in organic synthesis.

Synthesis

1,2,3,9-Tetrahydro-4(H)-carbazol-4-one

15128-52-6

4-Hydroxy carbazole

52602-39-8

Step 1: Preparation of 4-hydroxycarbazole; Nickel Nguyenay (35 g) was added to a reactor equipped with 1 L of water, followed by 1,2,3,9-tetrahydrocarbazol-4-one (50 g) and sodium hydroxide (15 g). The reaction mixture was heated to reflux and maintained for about 20 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was subsequently acidified to precipitate the solid product. The solid was collected by filtration and dried to give the crude 4-hydroxycarbazole. For further purification, the crude product can be dissolved in 10% sodium hydroxide solution, decolorized by activated carbon, and then the pH adjusted with dilute hydrochloric acid to precipitate the product. Finally, off-white to light gray 4-hydroxycarbazole crystals were obtained with a yield of about 50%.

References

[1] Journal of Organic Chemistry, 2006, vol. 71, # 22, p. 8384 - 8389
[2] Patent: WO2005/113502, 2005, A1. Location in patent: Page/Page column 14
[3] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 20, p. 2957 - 2961
[4] Journal of the Chemical Society, 1955, p. 3475
[5] Journal of Labelled Compounds and Radiopharmaceuticals, 2005, vol. 48, # 6, p. 407 - 419

Global Suppliers ( 512)
Supplier Tel Email Country ProdList Advantage
Jiujiang Yulite Pharmaceutical Technology Co., Ltd. 792-3901125 13222993784 sales@unite-pharm.com China 435 56
Shengyang Runze (Beijing) Technology Co., 17611011830 lyt001@syrz01.com China 179 58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd. 0513-82104991 18862997351 sales11@btcpharm.com China 859 58
Shanghai Taijilin Industrial Co., Ltd. 02150630626 17717886015 kate@tajilin.com China 1340 58
Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd 18317105404 marketing002@witofly.com China 1600 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81

View Latest Price from 4-Hydroxy carbazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
9H-Carbazol-4-ol pictures 2026-09-15 9H-Carbazol-4-ol
52602-39-8
1KG 98.0% 500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
4-Hydroxy carbazole pictures 2026-05-28 4-Hydroxy carbazole
52602-39-8
$9.00 1KG 99.9 1 ton Hebei Chuanghai Biotechnology Co,.LTD
9H-Carbazol-4-ol pictures 2026-03-20 9H-Carbazol-4-ol
52602-39-8
$10.00 100KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
4 HYDROXY 9(H)CARBAZOLE 4-Carbazolol SKF 106023 4-HYDROXYCARBAZOLE(CARVEDILOL INTERMEDIATE ) 9H-CARBAZOLE-4-OL p-HydroxycarBazole 9-H-CARBAZOL-4-OI 4-HYDROXYCARBAZOLE 98+% 4-Hydroxy carbazole(Carve. Intermediate) qiangjibianzuo 4-hidroxy carbazol 4-Hydroxycarbazole,9H-Carbazol-4-ol 4-Hydroxycarbazole, 98+% 5GR Carvedilol 4-Hydroxy Carbazole IMpurity 4-Hydroxycarbazole 52602-39-8 4-Hydroxycarbazole 95% 1-[3-[[oxo(propylamino)methyl]amino]phenyl]-3-propylurea 4-Hydroxycarbazole> 4-Hydoxycarbazole/9H-Carbazol-4-ol Carvedilol Intermediate 2 4-Hydroxycarbazole 9H-CARBAZOL-4-OL 52602-39-8 C12H19NO Building Blocks Carbazoles (for Conduting Polymer Research) Reagents for Conducting Polymer Research Carbazoles Heterocyclic Building Blocks Aromatics Heterocycles Carvedilol Intermediate PHARMACEUTICAL INTERMEDIATES Miscellaneous (intermediate of carvedilol) Aromatics Compounds Carbazoles Carbazoles (for Conduting Polymer Research) Functional Materials Reagents for Conducting Polymer Research 1