Antazoline
- CAS No.
- 91-75-8
- Chemical Name:
- Antazoline
- Synonyms
- Orosulfan;5512-M;Avissul;Azalone;Antastan;Antasten;Antistin;Antazolin;Antistine;Chemiopen
- CBNumber:
- CB8667315
- Molecular Formula:
- C17H19N3
- Molecular Weight:
- 265.35
- MDL Number:
- MFCD00047013
- MOL File:
- 91-75-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Antazoline | FA30098 | 1g | $150 |
| Antazoline | FA30098 | 2g | $150 |
| Antazoline | FA30098 | 5g | $285.55 |
| Antazoline | FA30098 | 10g | $542.6 |
| Antazoline | FA30098 | 25g | $999.5 |
| More product size | |||
| Melting point | 120-122° |
|---|---|
| Boiling point | 398.57°C (rough estimate) |
| Density | 0.9786 (rough estimate) |
| refractive index | 1.6080 (estimate) |
| pka | pKa 6.65(H2O t = 25 I = 0.05) (Uncertain) |
| form | A solid |
| color | White to off-white |
| Water Solubility | 663.4mg/L(30 ºC) |
| CAS DataBase Reference | 91-75-8(CAS DataBase Reference) |
| FDA UNII | DHA8014SS1 |
| NIST Chemistry Reference | Antazoline(91-75-8) |
| ATC code | R01AC04,R06AX05 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H302-H315-H319-H312 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Hazardous Substances Data | 91-75-8(Hazardous Substances Data) |
| Toxicity | LD50 oral in mouse: 398mg/kg |
Antazoline price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FA30098 | Antazoline | 91-75-8 | 1g | $150 | 2026-06-04 | Buy |
| Biosynth | FA30098 | Antazoline | 91-75-8 | 2g | $150 | 2026-06-04 | Buy |
| Biosynth | FA30098 | Antazoline | 91-75-8 | 5g | $285.55 | 2026-06-04 | Buy |
| Biosynth | FA30098 | Antazoline | 91-75-8 | 10g | $542.6 | 2026-06-04 | Buy |
| Biosynth | FA30098 | Antazoline | 91-75-8 | 25g | $999.5 | 2026-06-04 | Buy |
Antazoline Chemical Properties,Uses,Production
Chemical Properties
White, odorless crystalline powder with bitter taste. Sparingly soluble in alcohol and water; practically insoluble in benzene and ether.
Originator
Antistine HCl,Ciba,US,1948
Uses
Antihistaminic.
Definition
ChEBI: A member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug.
Manufacturing Process
15.4 parts of 2-chloromethylimidazoline hydrochloride, 45.8 parts of Nbenzylaniline and 150 parts of alcohol are heated in an oil bath at 100° to 110°C. After distilling off the alcohol, the reaction mass is maintained at this temperature for a further 3 hours and then triturated with water and 10 parts of sodium bicarbonate. The unconsumed benzylaniline is extracted with ether and the aqueous solution neutralized with dilute hydrochloric acid. By evaporating this solution and extracting the residue with alcohol there is obtained 2-(N-phenyl-N-benzylaminomethyl)imidazoline hydrochloride in the form of colorless crystals of melting point 227° to 229°C.
Therapeutic Function
Antihistaminic
Clinical Use
Antazoline is used for local application to the eye in allergic conjunctivitis.
Safety Profile
Poison by ingestion, subcutaneous, and intraperitoneal routes. An eye irritant. When heated to decomposition it emits toxic fumes of NOx.
Antazoline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3970 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32288 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Supplier | Advantage |
|---|---|
| career henan chemical co | 58 |
| CONIER CHEM AND PHARMA LIMITED | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
| BOC Sciences | 58 |
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| Amadis Chemical Company Limited | 58 |
| Mainchem Co., Ltd. | 55 |
| Bide Pharmatech Ltd. | 60 |
View Lastest Price from Antazoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Antazoline
91-75-8
|
$39.00-91.00 | 99.71% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-02-02 | Antazoline
91-75-8
|
$1.00 | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2024-08-20 | Antazoline
91-75-8
|
$7.00-13.00 | 1kg | 99.9% | 200ton | Hebei Ganmiao New material Technology Co., LTD |
-
- Antazoline
91-75-8
- $39.00-91.00
- 99.71%
- TargetMol Chemicals Inc.
-
- Antazoline
91-75-8
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Antazoline
91-75-8
- $7.00-13.00
- 99.9%
- Hebei Ganmiao New material Technology Co., LTD
