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1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE

CAS No.
129487-92-9
Chemical Name:
1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE
Synonyms
1-Boc-5-aMinoindoline;5-AMINO-1-BOC-2,3-DIHYDROINDOLE;1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE;1-Boc-2,3-dihydro-1H-indol-5-amine;tert-Butyl 5-aMinoindoline-1-carboxylate;2-Methyl-2-Propanyl 5-Amino-1-Indolinecarboxylate;tert-butyl 5-amino-2,3-dihydroindole-1-carboxylate;tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate;5-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;6-Amino-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester
CBNumber:
CB8683580
Molecular Formula:
C13H18N2O2
Molecular Weight:
234.29
MDL Number:
MFCD08059270
MOL File:
129487-92-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:42
Product description Number Pack Size Price
tert-Butyl5-Amino-2,3-dihydro-1H-indole-1-carboxylate T205238 50mg $45
5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 034352 500mg $98
5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 034352 1g $150
5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 034352 5g $525
tert-Butyl5-aminoindoline-1-carboxylate 5492AA 5g $637
More product size

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Properties

Boiling point 385.2±41.0 °C(Predicted)
Density 1.177±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form liquid
pka 5.44±0.20(Predicted)
color Brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT
HS Code  2933998090

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T205238 tert-Butyl5-Amino-2,3-dihydro-1H-indole-1-carboxylate 129487-92-9 50mg $45 2021-12-16 Buy
Matrix Scientific 034352 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 129487-92-9 500mg $98 2021-12-16 Buy
Matrix Scientific 034352 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 129487-92-9 1g $150 2021-12-16 Buy
Matrix Scientific 034352 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 129487-92-9 5g $525 2021-12-16 Buy
AK Scientific 5492AA tert-Butyl5-aminoindoline-1-carboxylate 129487-92-9 5g $637 2021-12-16 Buy
Product number Packaging Price Buy
T205238 50mg $45 Buy
034352 500mg $98 Buy
034352 1g $150 Buy
034352 5g $525 Buy
5492AA 5g $637 Buy

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Chemical Properties,Uses,Production

Synthesis

TERT-BUTYL 5-NITRO-1H-INDOLE-1-CARBOXYLATE

166104-19-4

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE

129487-92-9

The general procedure for the synthesis of tert-butyl 5-aminoindoline-1-carboxylate from tert-butyl 5-nitro-1H-indole-1-carboxylate is as follows: XII; tert-butyl 5-amino-2,3-dihydro-indole-1-carboxylate; 6.8 g of tert-butyl 5-nitro-1H-indole-1-carboxylate was dissolved in 120 mL of methanol. To this solution was added 600 mg of 10% palladium carbon catalyst, followed by a hydrogenation reaction at room temperature for 1.5 hours. Upon completion of the reaction, the catalyst was removed by filtration and the solvent was evaporated under reduced pressure. The final product was 6 g of tert-butyl 5-aminoindoline-1-carboxylate in 100% yield of the theoretical value. The product was analyzed by mass spectrometry (ESI+) and showed m/z = 235 [M + H]+.

References

[1] Patent: WO2008/113760, 2008, A2. Location in patent: Page/Page column 92
[2] Patent: US2017/50964, 2017, A1. Location in patent: Paragraph 0734
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 23, p. 6481 - 6488
[4] Synthesis, 2007, # 10, p. 1509 - 1512

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Preparation Products And Raw materials

Global( 87)Suppliers
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Capot Chemical Co.,Ltd.
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Chembon Pharmaceutical Co., Ltd.
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ATK CHEMICAL COMPANY LIMITED
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career henan chemical co
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Alchem Pharmtech,Inc.
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Shanghai UCHEM Inc.
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Zhejiang J&C Biological Technology Co.,Limited
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Hefei TNJ Chemical Industry Co.,Ltd.
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Nanjing Yushan Wanfang Biotechnology Co., Ltd.
+86-025-84918180 +86-18014482516 3552541679@qq.com China 997 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8467 58

View Lastest Price from 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE pictures 2019-09-02 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE
129487-92-9
US $1.00 / KG 1KG 98% 1lg; 2kg; 5kg; 10kg; 100kg Career Henan Chemical Co

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE Spectrum

tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate 1-Boc-5-aMinoindoline 2-Methyl-2-Propanyl 5-Amino-1-Indolinecarboxylate 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester >=97% 6-Amino-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester 1-Boc-2,3-dihydro-1H-indol-5-amine 5-AMINO-1-BOC-2,3-DIHYDROINDOLE 5-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER tert-butyl 5-amino-2,3-dihydroindole-1-carboxylate 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE tert-Butyl 5-aMinoindoline-1-carboxylate 1H-Indole-1-carboxylic acid, 5-aMino-2,3-dihydro-, 1,1-diMethylethyl ester 129487-92-9 pharmacetical