Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-Boc-5-amino-2,3-dihydro-indole

1-Boc-5-amino-2,3-dihydro-indole

1-Boc-5-amino-2,3-dihydro-indole Structure
1-Boc-5-amino-2,3-dihydro-indole structure
CAS No.
129487-92-9
Chemical Name:
1-Boc-5-amino-2,3-dihydro-indole
Synonyms
1-Boc-5-aMinoindoline;5-AMINO-1-BOC-2,3-DIHYDROINDOLE;1-Boc-5-amino-2,3-dihydro-indole;1-Boc-2,3-dihydro-1H-indol-5-amine;tert-Butyl 5-aMinoindoline-1-carboxylate;2-Methyl-2-Propanyl 5-Amino-1-Indolinecarboxylate;tert-butyl 5-amino-2,3-dihydroindole-1-carboxylate;tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate;5-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;6-Amino-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester
CBNumber:
CB8683580
Molecular Formula:
C13H18N2O2
Molecular Weight:
234.29
MDL Number:
MFCD08059270
MOL File:
129487-92-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:51
Request For Quotation

1-Boc-5-amino-2,3-dihydro-indole Properties

Boiling point 385.2±41.0 °C(Predicted)
Density 1.177±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 5.44±0.20(Predicted)
form liquid
color Brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT
HS Code  2933998090

1-Boc-5-amino-2,3-dihydro-indole price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth EFA48792 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 129487-92-9 5g $531 2026-06-04 Buy
Apolloscientific OR305256 tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate >98% 129487-92-9 250mg $22 2026-06-04 Buy
Apolloscientific OR305256 tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate >98% 129487-92-9 1g $49 2026-06-04 Buy
Apolloscientific OR305256 tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate >98% 129487-92-9 5g $195 2026-06-04 Buy
Apolloscientific OR305256 tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate >98% 129487-92-9 25g $799 2026-06-04 Buy
Product number Packaging Price Buy
EFA48792 5g $531 Buy
OR305256 250mg $22 Buy
OR305256 1g $49 Buy
OR305256 5g $195 Buy
OR305256 25g $799 Buy

1-Boc-5-amino-2,3-dihydro-indole Chemical Properties, Uses, Production

Synthesis

TERT-BUTYL 5-NITRO-1H-INDOLE-1-CARBOXYLATE

166104-19-4

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE

129487-92-9

The general procedure for the synthesis of tert-butyl 5-aminoindoline-1-carboxylate from tert-butyl 5-nitro-1H-indole-1-carboxylate is as follows: XII; tert-butyl 5-amino-2,3-dihydro-indole-1-carboxylate; 6.8 g of tert-butyl 5-nitro-1H-indole-1-carboxylate was dissolved in 120 mL of methanol. To this solution was added 600 mg of 10% palladium carbon catalyst, followed by a hydrogenation reaction at room temperature for 1.5 hours. Upon completion of the reaction, the catalyst was removed by filtration and the solvent was evaporated under reduced pressure. The final product was 6 g of tert-butyl 5-aminoindoline-1-carboxylate in 100% yield of the theoretical value. The product was analyzed by mass spectrometry (ESI+) and showed m/z = 235 [M + H]+.

References

[1] Patent: WO2008/113760, 2008, A2. Location in patent: Page/Page column 92
[2] Patent: US2017/50964, 2017, A1. Location in patent: Paragraph 0734
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 23, p. 6481 - 6488
[4] Synthesis, 2007, # 10, p. 1509 - 1512

1-Boc-5-amino-2,3-dihydro-indole Preparation Products And Raw materials

Raw materials

1H-Indole-1-carboxylic acid, 2,3-dihydro-5-nitro-, 1,1-diMethylethyl ester tert-Butyl 5-nitro-1H-indole-1-carboxylate Methanol Hydrogen

Preparation Products

1-Boc-5-amino-2,3-dihydro-indole Suppliers

Global Suppliers ( 89)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Carbott PharmTech Inc. 0535-6385396 info@carbottpharm.com China 996 56
Chembon Pharmaceutical Co., Ltd. 028-84252981 18583719936 sales@chembon.com.cn China 854 64
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60
Shanghai Xiannuo Biotechnology Co., Ltd. 021-50718719 13918719472 China 978 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Shanghai Run-Biotech Co., Ltd. 021-57171705 13817537615 sales@run-biotech.com China 2280 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Supplier Advantage
J & K SCIENTIFIC LTD. 76
PharmaBlock Sciences (Nanjing),Inc. 55
Carbott PharmTech Inc. 56
Chembon Pharmaceutical Co., Ltd. 64
Spectrum Chemical Manufacturing Corp. 60
Shanghai Xiannuo Biotechnology Co., Ltd. 58
Nanjing Norris-Pharm Technology Co., Ltd 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Shanghai Run-Biotech Co., Ltd. 58
Bide Pharmatech Ltd. 60

View Latest Price from 1-Boc-5-amino-2,3-dihydro-indole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE pictures 2019-09-02 1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE
129487-92-9
 $1.00 1KG 98% 1lg; 2kg; 5kg; 10kg; 100kg Career Henan Chemical Co

1-Boc-5-amino-2,3-dihydro-indole Spectrum

1-BOC-5-AMINO-2,3-DIHYDRO-INDOLE(129487-92-9)1HNMR

129487-92-9 (1-Boc-5-amino-2,3-dihydro-indole) Related Search:

(4-Amino-2-methyl-phenyl)-carbamic acid tert-butyl ester 1-Boc-5-amino-2,3-dihydro-indole 4-(tert-Butoxycarbonylamino)aniline [2-(3-Amino-phenyl)-ethyl]-carbamic acid tert-butyl ester 1-Boc-indoline
tert-butyl 5-bromoindoline-1-carboxylate tert-butyl 5-bromofuran-2-carboxylate

1of2

tert-Butyl 5-amino-2,3-dihydro-1H-indole-1-carboxylate 1-Boc-5-aMinoindoline 2-Methyl-2-Propanyl 5-Amino-1-Indolinecarboxylate 5-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester >=97% 6-Amino-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester 1-Boc-2,3-dihydro-1H-indol-5-amine 5-AMINO-1-BOC-2,3-DIHYDROINDOLE 5-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER tert-butyl 5-amino-2,3-dihydroindole-1-carboxylate tert-Butyl 5-aMinoindoline-1-carboxylate 1H-Indole-1-carboxylic acid, 5-aMino-2,3-dihydro-, 1,1-diMethylethyl ester 1-Boc-5-amino-2,3-dihydro-indole 129487-92-9 pharmacetical