H-AVPIAQK-OH
- CAS No.
- 401913-57-3
- Chemical Name:
- H-AVPIAQK-OH
- Synonyms
- AVPIAQK;H-AVPIAQK-OH;SMAC N7 PROTEIN;SMAC-N7 PEPTIDE;H-ALA-VAL-PRO-ILE-ALA-GLN-LYS-OH;SMAC PROTEIN (1-7) (HUMAN, MOUSE);Smac-N7、Second Mitochondria-derived Activator of Caspase;L-Lysine, L-alanyl-L-valyl-L-prolyl-L-isoleucyl-L-alanyl-L-glutaminyl-;Smac-N7 Peptide trifluoroacetate salt H-Ala-Val-Pro-Ile-Ala-Gln-Lys-OH trifluoroacetate salt;Mitochondrial Diablo HoMolog (1-7) (huMan, Mouse), Second Mitochondria-derived Activator of Caspase (1-7) (huMan, Mouse), SMac Protein (1-7) (huMan, Mouse)
- CBNumber:
- CB8685443
- Molecular Formula:
- C33H59N9O9
- Molecular Weight:
- 725.88
- MDL Number:
- MFCD03458534
- MOL File:
- 401913-57-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 1147.315±65.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.223±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | -20°C |
| form | lyophilized solid |
| pka | 3.274±0.10(predicted) |
| color | white |
| Water Solubility |
water: 1mg/mL DMSO: 5mg/mL |
| Sequence | Ala-Val-Pro-Ile-Ala-Gln-Lys |
| UNSPSC Code | 12352200 |
H-AVPIAQK-OH price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 567370 | Smac-N7 Peptide | 401913-57-3 | 5mg | $437 | 2023-01-07 | Buy |
| Biosynth | PP45749 | H-AVPIAQK-OH | 1mg | $165 | 2026-06-04 | Buy | |
| Biosynth | PP45749 | H-AVPIAQK-OH | 10mg | $190 | 2026-06-04 | Buy | |
| Biosynth | FS109919 | Smac-N7 Peptide trifluoroacetate salt | 401913-57-3 | 1mg | $274.44 | 2026-06-04 | Buy |
| Biosynth | PP45749 | H-AVPIAQK-OH | 100mg | $349 | 2026-06-04 | Buy |
H-AVPIAQK-OH Chemical Properties,Uses,Production
Uses
Smac-N7 peptide, the seven N-terminal amino acid of the mitochondrial protein Smac (second mitochondria-derived activator of caspase), cannot pass through the cell membrane[1].
Biological Activity
Cell permeable: no', 'Kd ~800 nM in binding to the BIR2 and BIR3 (baculovirus IAP repeat) domains of XIAP (X-linked inhibitor of apoptosis proteins)', 'Primary Target
Promotes the catalytic activity of caspase-9 in the presence of XIAP', 'Product does not compete with ATP.', 'Reversible: no
References
[1] S Heckl, et al. A novel polyarginine containing Smac peptide conjugate that mediates cell death in tumor and healthy cells. Med Chem. 2008 Jul;4(4):348-54. DOI:10.2174/157340608784872217
H-AVPIAQK-OH Preparation Products And Raw materials
Raw materials
Preparation Products
H-AVPIAQK-OH Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 | Caroline@youngshechem.com | China | 4725 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Nanjing TGpeptide Biotechnology Co.,Ltd. | 18115476705 | sales@tgpeptide.com | China | 3058 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 13336126704 | sales7@gotopbio.com | China | 2987 | 58 |
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