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L-Alaninol

CAS No.
2749-11-3
Chemical Name:
L-Alaninol
Synonyms
L-ALANINOL;2-AMINOPROPANOL;H-ALA-OL;310399;L-2-Amino-1-propanol;(S)-2-AMINO-1-PROPANOL;L-Ala-ol;L-Alanino;L-ALANILOL;H-ALANINOL
CBNumber:
CB8693194
Molecular Formula:
C3H9NO
Molecular Weight:
75.11
MDL Number:
MFCD00064412
MOL File:
2749-11-3.mol
MSDS File:
SDS
Last updated:2026-01-13 11:27:12
Product description Number Pack Size Price
(S)-(+)-2-Amino-1-propanol 98% A76206 1g $48.7
(S)-(+)-2-Amino-1-propanol 98% A76206 10g $302
(S)-(+)-2-Amino-1-propanol >98.0%(GC)(T) A1085 1mL $28
(S)-(+)-2-Amino-1-propanol >98.0%(GC)(T) A1085 5mL $93
(S)-(+)-2-Amino-1-propanol >98.0%(GC)(T) A1085 25mL $277
More product size

L-Alaninol Properties

Melting point -2°C
alpha 21.8 º (c=2,ethanol)
Boiling point 72-73 °C11 mm Hg(lit.)
Density 0.965 g/mL at 25 °C(lit.)
refractive index n20/D 1.450
Flash point 145 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform, Methanol (Slightly)
Water Solubility Completely miscible in water
pka 12.88±0.10(Predicted)
form Oily Liquid
color Clear colorless to yellow
Specific Gravity 0.96
optical activity [α]20/D +18°, neat
Sensitive Hygroscopic
BRN 1718865
InChI 1S/C3H9NO/c1-3(4)2-5/h3,5H,2,4H2,1H3/t3-/m0/s1
InChIKey BKMMTJMQCTUHRP-VKHMYHEASA-N
SMILES C[C@H](N)CO
CAS DataBase Reference 2749-11-3(CAS DataBase Reference)
FDA UNII V403GH89L1
NIST Chemistry Reference 1-Propanol, 2-amino-, (S)-(2749-11-3)
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C,Xi
Risk Statements  34-36/37/38
Safety Statements  26-36/37/39-45-36
RIDADR  UN 2735 8/PG 2
WGK Germany  3
10-23
HazardClass  8
PackingGroup  III
HS Code  29221990
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Skin Corr. 1B
Limited Quantities 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
1
3 0

L-Alaninol price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A76206 (S)-(+)-2-Amino-1-propanol 98% 2749-11-3 1g $48.7 2025-07-31 Buy
Sigma-Aldrich A76206 (S)-(+)-2-Amino-1-propanol 98% 2749-11-3 10g $302 2025-07-31 Buy
TCI Chemical A1085 (S)-(+)-2-Amino-1-propanol >98.0%(GC)(T) 2749-11-3 1mL $28 2025-07-31 Buy
TCI Chemical A1085 (S)-(+)-2-Amino-1-propanol >98.0%(GC)(T) 2749-11-3 5mL $93 2025-07-31 Buy
TCI Chemical A1085 (S)-(+)-2-Amino-1-propanol >98.0%(GC)(T) 2749-11-3 25mL $277 2025-07-31 Buy
Product number Packaging Price Buy
A76206 1g $48.7 Buy
A76206 10g $302 Buy
A1085 1mL $28 Buy
A1085 5mL $93 Buy
A1085 25mL $277 Buy

L-Alaninol Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid

Uses

S-(+)-2-Amino-1-propanol is an aliphatic amino alcohol shown to induce an antiproliferative effect in B16 melanoma cells. S-(+)-2-Amino-1-propanol is used in the preparation of oxazolines which are of ten used as ligands in homogeneous catalysis.

Uses

(S)-(+)-2-Amino-1-propanol (L-Alaninol) may be used in the preparation of unsymmetrical tridentate Schiff base ligands via condensation with carbonyl compounds. It may also be used as a chiral auxillary for the preparation of tert-butyl 4-N-[(2-hydroxy-1-(S)-methyl)ethylamino]-2-methylene-4-(S)-phenyl-butyrate.

Definition

ChEBI: (S)-2-aminopropan-1-ol is a 2-aminopropan-1-ol that has S-configuration. It is a conjugate base of a (S)-2-aminopropan-1-ol(1+). It is an enantiomer of a (R)-2-aminopropan-1-ol.

Biochem/physiol Actions

Pseudomonas sp. strain KIE171 was able to grow with L-alaninol [S-(+)-2-amino-1-propanol] as the sole carbon source[1]. Wsch et al. found that mutant KIE171-BI transformed isopropylamine to L-alaninol, mutant KIE171-BII failed to do so.

Synthesis

Simply produce L-alaninol in high yield and good reproducibility by directly reducing an inorganic acid salt of an L-alanine ester with NaBH4. 3.0 mol of NaBH 4 was added and dissolved in 560 ml of cold water, and L-alanine ethyl ester hydrochloride 1. A solution of 0 mol dissolved in 560 ml of ethanol was added. The mixture was added dropwise at 20 ° C. over 5 hours and further aged at 20 to 28 ° C. to complete the reaction. After the reaction, excess NaBH 4 was decomposed with acetone, 1000 ml of ethyl acetate was introduced, and the precipitated inorganic substance was separated by filtration. The lower aqueous layer portion of the filtrate was extracted with 600 ml of ethyl acetate; the ethyl acetate layer was distilled under reduced pressure to remove the solvent and then vacuum distilled to yield L-alaninol.

Purification Methods

Purify it as for S-2-amino-3-methylbutan-1-ol below. [Beilstein 4 IV 1615.]

References

[1] Susana I de Azevedo Wsch. “Transformation of isopropylamine to L-alaninol by Pseudomonas sp. strain KIE171 involves N-glutamylated intermediates.”Applied and Environmental Microbiology (2002): 68.

485-47-2
2491-20-5
2749-11-3
Synthesis of L-Alaninol from Ninhydrin hydrate and L-Alanine methyl ester hydrochloride
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View Lastest Price from L-Alaninol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-Ala-ol pictures 2026-02-02 H-Ala-ol
2749-11-3
US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
L-Alaninol pictures 2026-01-05 L-Alaninol
2749-11-3
US $0.00 / removed 99.72% 10g TargetMol Chemicals Inc.
S-(+)-2-Amino-1-propano pictures 2025-12-03 S-(+)-2-Amino-1-propano
2749-11-3
US $125.00 / ASSAYS 1KG 99% 100kg Baoji Guokang Healthchem Co., Ltd.
  • H-Ala-ol pictures
  • H-Ala-ol
    2749-11-3
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • L-Alaninol pictures
  • L-Alaninol
    2749-11-3
  • US $0.00 / removed
  • 99.72%
  • TargetMol Chemicals Inc.
H-L-ALA-OL H-ALANINOL H-ALA-OL H-ALA-OL S-(+)-2 AMINO-PROPANOL 2-AMINOPROPANOL L-(+)-ALANINOL L-ALANINOL L-ALANILOL L-(+)-2-AMINO PROPANOL L-2-AMINO-PROPANOL L-Alaninols-(+)-2-amino propanol (2S)-(+)-2-Aminopropan-1-ol L-Alaninol, (2S)-(+)-2-Amino-1-hydroxypropane L-Alaninol SynonyMs: (S)-(+)-2-AMino-1-propanol (S)-(+)-2-AMino-1-propanol 98% 2-(2-AMinoethyl)-1,3-dioxolane, 98.0%(GC&T L-Alanino 310399 (S)-(+)-2-AMino-1-propanol, 98% 1GR L-2-Amino-1-propanol L-Alaninol≥ 99.9% (GC, Chiral purity) L-Alaninol,99%e.e. (S)-(+)-2-AMINO-1-PROPANOL (S)-2-AMINO-1-PROPANOL (S)-2-AMINO-PROPAN-1-OL L-Alaninol,98+% L-Alaninol (L-2-Amino-1-propanol) (+)-2-Aminopropan-1-ol (S)-(+)-Alaninol Aminopropanol,95% (S)-(+)-2-AMINO-1-PROPANOL, 98% (97% EE/ L-Alaninol(L-2-Amino-Propanol) L-Ala-ol VL-Alaninol S-(+)-ALANINOL:L-ALANINOL (S)-(+)-2-Amino-1-propanol,98% S-(+)-2-Alaninol (L- [(2S)-1-hydroxypropan-2-yl]ammonium (S)-(+)-2-Amino-1-propanol > 1-Propanol, 2-amino-, (2S)- (S)-(+)-2-AMINO-L-PROPANOL S-(+)-2-Amino-1-propanol USP/EP/BP L-Alaninol, 98% [(S)-(+)-2-Amino-1-propanol] Pirimicarb Impurity 5 (Pirimiphos Ethyl) (S)-(+)-2-Amino-1-propanol 2749-11-3 2749-11-2 11/3/2749 2749-11-03 27-49-1 C3H9NO Building Blocks Amino Acid Derivatives Chiral Resolution Reagents Chiral Resolving Reagents Organic Building Blocks Specialty Synthesis Oxygen Compounds