3,5-Dimethylisoxazole-4-carboxylic acid
- CAS No.
- 2510-36-3
- Chemical Name:
- 3,5-Dimethylisoxazole-4-carboxylic acid
- Synonyms
- AKOS PAO-1555;BUTTPARK 27\08-43;RARECHEM AL BO 0995;TIMTEC-BB SBB004158;3,5-dimethyl-4-isoxazolecarboxylate;diMethyl-1,2-oxazole-4-carboxylic acid;3,5-DIMETHYLISOXASOLE-4-CARBOXYLIC ACID;3,5-DIMETHYL-4-ISOXAZOLECARBOXYLIC ACID;3,5-Dimethylisoxazole-4-carboxylic acid;4-Isoxazolecarboxylic acid, 3,5-dimethyl-
- CBNumber:
- CB8710204
- Molecular Formula:
- C6H7NO3
- Molecular Weight:
- 141.12
- MDL Number:
- MFCD00051657
- MOL File:
- 2510-36-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 141-145 °C(lit.) |
|---|---|
| Boiling point | 258.14°C (rough estimate) |
| Density | 1.3710 (rough estimate) |
| refractive index | 1.4890 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 2.53±0.32(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| BRN | 115819 |
| InChI | 1S/C6H7NO3/c1-3-5(6(8)9)4(2)10-7-3/h1-2H3,(H,8,9) |
| InChIKey | IJEUISLJVBUNRE-UHFFFAOYSA-N |
| SMILES | Cc1noc(C)c1C(O)=O |
| CAS DataBase Reference | 2510-36-3(CAS DataBase Reference) |
| FDA UNII | HG288MUN8Q |
| NIST Chemistry Reference | 3,5-Dimethylisoxazole-4-carboxylic acid(2510-36-3) |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| Safety Statements | 24/25-36-22 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| NFPA 704 |
|
3,5-Dimethylisoxazole-4-carboxylic acid price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 637653 | 3,5-Dimethylisoxazole-4-carboxylic acid 98% | 2510-36-3 | 5g | $104 | 2022-05-15 | Buy |
| TCI Chemical | D4603 | 3,5-Dimethylisoxazole-4-carboxylic Acid >98.0%(HPLC)(T) | 2510-36-3 | 1g | $58 | 2026-04-30 | Buy |
| TCI Chemical | D4603 | 3,5-Dimethylisoxazole-4-carboxylic Acid >98.0%(HPLC)(T) | 2510-36-3 | 5g | $203 | 2026-04-30 | Buy |
| Apolloscientific | OR1283 | 3,5-Dimethylisoxazole-4-carboxylic acid 95 | 2510-36-3 | 5g | $59 | 2026-06-04 | Buy |
| Apolloscientific | OR1283 | 3,5-Dimethylisoxazole-4-carboxylic acid 95 | 2510-36-3 | 10g | $73 | 2026-06-04 | Buy |
3,5-Dimethylisoxazole-4-carboxylic acid Chemical Properties, Uses, Production
Chemical Properties
light beige powder
Synthesis
17147-42-1
2510-36-3
General procedure for the synthesis of 3,5-dimethylisoxazole-4-carboxylic acid from ethyl 3,5-dimethylisoxazole-4-carboxylate: to a mixture of ethyl 3,5-dimethyl-4-isoxazolecarboxylate (2.4 g, 14 mmol) in a solution of tetrahydrofuran (THF, 8 mL) and methanol (MeOH, 8 mL), an aqueous solution of 5 N sodium hydroxide (NaOH) (8.5 mL ). The reaction mixture was stirred at room temperature for 8 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure, followed by acidification with 6 N aqueous hydrochloric acid (HCl) to pH = 2. The precipitated white solid product was filtered, washed with water, and dried to afford 3,5-dimethylisoxazole-4-carboxylic acid (2.1 g, 94.0% yield). The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 2.72 (s, 3H), 2.49 (s, 3H).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 17, p. 2879 - 2884
[2] Justus Liebigs Annalen der Chemie, 1893, vol. 277, p. 174
[3] Journal of the American Chemical Society, 1967, vol. 89, p. 5461 - 5462
3,5-Dimethylisoxazole-4-carboxylic acid Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| New Energy Chemicals | 0515-82159099 13770142076 | info@njuchem.com | China | 251 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Latest Price from 3,5-Dimethylisoxazole-4-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
2510-36-3
|
$1.00 | 1kg | 98% | 100KG | Career Henan Chemical Co | |
 |
2019-07-06 | 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
2510-36-3
|
$8.00 | 1kg | 99% | 10tons | Career Henan Chemical Co |
-
- 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
2510-36-3
- $1.00
- 98%
- Career Henan Chemical Co
-
- 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
2510-36-3
- $8.00
- 99%
- Career Henan Chemical Co
2510-36-3 (3,5-Dimethylisoxazole-4-carboxylic acid) Related Search:
1of4
