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FURA-FF, AM

FURA-FF, AM Structure
FURA-FF, AM structure
CAS No.
348079-12-9
Chemical Name:
FURA-FF, AM
Synonyms
FURA-FF, AM;Fura-FF, AM [Fura-2FF, AM] *CAS 348079-12-9*;5-Oxazolecarboxylic acid, 2-[6-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-[2-[6-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-2,3-difluorophenoxy]ethoxy]-2-benzofuranyl]-, (acetyloxy)methyl ester
CBNumber:
CB8741336
Molecular Formula:
C43H43F2N3O24
Molecular Weight:
1023.8
MDL Number:
MFCD03456899
MOL File:
348079-12-9.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08
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FURA-FF, AM Properties

Boiling point 971.5±75.0 °C(Predicted)
Density 1.447±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: soluble
form A solid
pka 0.36±0.50(Predicted)
color Light yellow to yellow

FURA-FF, AM price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20416 Fura-FF AM ≥90% 348079-12-9 50μg $70 2026-04-30 Buy
ChemScene CS-0109218 Fura-FF AM 95.00% 348079-12-9 50??g $158 2026-06-04 Buy
Product number Packaging Price Buy
20416 50μg $70 Buy
CS-0109218 50??g $158 Buy

FURA-FF, AM Chemical Properties, Uses, Production

Description

Fura-FF AM is a cell-permeable acetoxymethyl ester of the fluorescence calcium indicator fura-FF (potassium salt) . As fura-FF AM enters cells, it is hydrolyzed by intracellular esterases to produce fura-FF. Fura-FF is a difluorinated derivative of the calcium indicator fura-2 . Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation.1 Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd(calcium) = 6 and 0.14 μM, respectively).1,2 However, the spectral properties of fura-FF and fura-2 are similar with fura-FF displaying excitation/emission spectra of 365/514 nm in the absence of calcium, with a shift to 339/507 nm in the presence of a high calcium concentration.3 Low affinity calcium dyes, including fura-FF, are preferred for studying compartments with high concentrations of calcium, such as mitochondria, or in cell systems that have relatively low calcium buffering capacities, such as neuronal dendrites and spines.4,5,6

Uses

Fura-FF AM is a cell-permeable acetoxymethyl ester of fura-FF, a dluorescent calcium indicator. Fura-FF AM is hydrolyzed by intracellular esterases to release fura-FF in cells. Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Compared to fura-2, fura-FF has a low affinity for calcium and is suitable for studying compartments with high concentrations of calcium.

References

1. Hyrc, K.L., Bownik, J.M., and Goldberg, M.P. Ionic selectivity of low-affinity ratiometric calcium indicators: mag-Fura-2, Fura-2FF and BTC Cell Calcium 27(2),75-86(2000).
2. Grynkiewicz, G., Poenie, M., and Tsien, R.Y. A new generation of Ca2+ indicators with greatly improved fluorescence properties J. Biol. Chem. 260(6),3440-3450(1985).
3. Ruggiu, A.A., Bannwarth, M., and Johnsson, K. Fura-2FF-based calcium indicator for protein labeling Org. Biomol. Chem. 8(15),3398-3401(2010).
4. Aponte, Y., Bischofberger, J., and Jonas, P. Efficient Ca2+ buffering in fast-spiking basket cells of rat hippocampus J. Physiol. 586(8),2061-2075(2008).
5. Canepari, M., Vogt, K., and Zecevic, D. Combining voltage and calcium imaging from neuronal dendrites Cell. Mol. Neurobiol. 28(8),1079-1093(2008).
6. Marcu, R., Neely, C.K., Karamanlidis, G., et al. Multi-parameter measurement of the permeability transition pore opening in isolated mouse heart mitochondria J. Vis. Exp. 67:4131,(2012).

FURA-FF, AM Preparation Products And Raw materials

Raw materials

Preparation Products

FURA-FF, AM Suppliers

Global Suppliers ( 27)
Supplier Tel Email Country ProdList Advantage
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7982 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Xi'an Biolite Biotech, Inc. 029-029-68064558 18502920169 xiaodong@tjbiolite.com China 2949 58
Absin Bioscience Inc. 13761418683 fengmj@univ-bio.com China 12045 58
Supplier Advantage
Beijing Ouhe Technology Co., Ltd 60
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
TargetMol Chemicals Inc. 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Xi'an Biolite Biotech, Inc. 58
Absin Bioscience Inc. 58

View Latest Price from FURA-FF, AM manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fura-FF AM pictures 2026-07-15 Fura-FF AM
348079-12-9
 $229.00 10g TargetMol Chemicals Inc.
  • Fura-FF AM pictures
  • Fura-FF AM
    348079-12-9
  • $229.00
  • TargetMol Chemicals Inc.

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Fura-FF, AM [Fura-2FF, AM] *CAS 348079-12-9* FURA-FF, AM 5-Oxazolecarboxylic acid, 2-[6-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-[2-[6-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-2,3-difluorophenoxy]ethoxy]-2-benzofuranyl]-, (acetyloxy)methyl ester 348079-12-9