ChemicalBook >> CAS DataBase List >>9-METHOXYCANTHIN-6-ONE

9-METHOXYCANTHIN-6-ONE

CAS No.
74991-91-6
Chemical Name:
9-METHOXYCANTHIN-6-ONE
Synonyms
9-METHOXYCANTHIN-6-ONE;8-methoxycanthin-6-one;9-Methoxycanthin-6-one, 10 mM in DMSO;9-Methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one;6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one,9-methoxy-;explants,fibrous,Inhibitor,9 Methoxycanthin 6 one,inhibit,anti-tumour,roots,cultures,9Methoxycanthin6one,callus
CBNumber:
CB8757982
Molecular Formula:
C15H10N2O2
Molecular Weight:
250.25
MDL Number:
MFCD07779123
MOL File:
74991-91-6.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
9-Methoxycanthin-6-one 99.80% CS-0058761 5mg $217
9-Methoxycanthin-6-one 99.80% CS-0058761 10mg $347
9-Methoxycanthin-6-one 99.80% CS-0058761 25mg $650
9-Methoxycanthin-6-one 99.80% CS-0058761 50mg $964
9-Methoxycanthin-6-one 99.80% CS-0058761 100mg $1284
More product size

9-METHOXYCANTHIN-6-ONE Properties

Melting point 181.6 °C(Solv: acetone (67-64-1))
Boiling point 384.1±42.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
pka 4.49±0.20(Predicted)
form Solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

9-METHOXYCANTHIN-6-ONE price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0058761 9-Methoxycanthin-6-one 99.80% 74991-91-6 5mg $217 2026-06-04 Buy
ChemScene CS-0058761 9-Methoxycanthin-6-one 99.80% 74991-91-6 10mg $347 2026-06-04 Buy
ChemScene CS-0058761 9-Methoxycanthin-6-one 99.80% 74991-91-6 25mg $650 2026-06-04 Buy
ChemScene CS-0058761 9-Methoxycanthin-6-one 99.80% 74991-91-6 50mg $964 2026-06-04 Buy
ChemScene CS-0058761 9-Methoxycanthin-6-one 99.80% 74991-91-6 100mg $1284 2026-06-04 Buy
Product number Packaging Price Buy
CS-0058761 5mg $217 Buy
CS-0058761 10mg $347 Buy
CS-0058761 25mg $650 Buy
CS-0058761 50mg $964 Buy
CS-0058761 100mg $1284 Buy

9-METHOXYCANTHIN-6-ONE Chemical Properties,Uses,Production

Uses

9-Methoxycanthin-6-one is a canthin-6-one alkaloid from the intact plant parts and callus cultures of Eurycoma longifolia (Tongkat Ali). Canthin-6-one alkaloids were evaluated for their cytotoxic activity against a HT-1080 human fibrosarcoma cell line.

Definition

ChEBI: An indole alkaloid that is the 9-methoxy derivative of canthin-6-one. Isolated from Eurycoma longifolia and Simaba multiflora, it exhibits cytotoxic activity towards human cancer cell lines.

Synthesis

1kg of bitter wood herbs were crushed and extracted with 10 liters of 75% ethanol by heating for 2 times, each time for 2 hours, combined with the extract, vacuum recovery of ethanol at 60 , the pH was adjusted to 11 with concentrated ammonia, extracted with equal volume of ethyl acetate for 2 times, combined with the extract, recovered the ethyl acetate, the residue was dissolved with 0.5% hydrochloric acid, and then the above steps were repeated with the concentration of ammonia to adjust pH - - ethyl acetate extraction. The total alkaloid was 17.1g. 600g of column chromatography silica gel (200-300 mesh) was loaded with chloroform, 10g of total alkaloid was dissolved in anhydrous ethanol, and 15g of column chromatography silica gel (100-120 mesh) was mixed with samples, and the samples were eluted with chloroform-methanol gradient after sample elution (starting solvent was chloroform), and the samples were collected in 250ml. Once, TLC check, combined with the same items, recovery of solvent, the total alkaloids of refined bitter wood 4.1g, high performance liquid chromatography (HPLC) method, 4,5-dimethoxy ferrocyanidinone, 4-methoxy-5-hydroxy ferrocyanidinone, the total content of the two according to the weight/weight of 83% (w/w). 600g of column chromatography silica gel (200-300 mesh) with chloroform wet method to load the column, take 10g of total alkaloids dissolved in anhydrous ethanol, and then dissolve the total alkaloids into the water. Alkaloids dissolved in anhydrous ethanol, 15g column chromatography silica gel (100-120 mesh) mixing samples, on the sample to chloroform methanol gradient elution (starting solvent for chloroform), 250ml collected once, TLC check, combined with the same item, repeated silica gel column chromatography, can be obtained 4,5-dimethoxy ferrocephalos 2.1g, HPLC normalization check purity of 98.7%; can be obtained 4-methoxy-5 4-methoxy-5-hydroxyferricyclohexanone 1.7g, HPLC normalization check purity 98.2%.

9-METHOXYCANTHIN-6-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 65)Suppliers
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TargetMol Chemicals Inc.
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BOC Sciences
16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc.
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Zibo Hangyu Biotechnology Development Co., Ltd
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Aladdin Scientific
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J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 aileen@chemfaces.com China 6904 55
Shanghai YuanYe Biotechnology Co., Ltd. 13636370518 shyysw007@163.com China 89667 60

View Lastest Price from 9-METHOXYCANTHIN-6-ONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
9-Methoxycanthin-6-one pictures 2026-07-27 9-Methoxycanthin-6-one
74991-91-6
$67.00-263.00 99.89% 10g TargetMol Chemicals Inc.

9-METHOXYCANTHIN-6-ONE Spectrum

9-METHOXYCANTHIN-6-ONE 9-Methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one 8-methoxycanthin-6-one 6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one,9-methoxy- explants,fibrous,Inhibitor,9 Methoxycanthin 6 one,inhibit,anti-tumour,roots,cultures,9Methoxycanthin6one,callus 9-Methoxycanthin-6-one, 10 mM in DMSO 74991-91-6 Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals