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Trimethylamine hydrochloride

CAS No.
593-81-7
Chemical Name:
Trimethylamine hydrochloride
Synonyms
TRIMETHYLAMMONIUM CHLORIDE;TRIMETHYLAMINE HCL;FEMA 3241;Trimthylamine bydrochloride;N, N-DIMETHYLMETHYLAMINE HCL;Trimethylamine monohydrochloride;Trimethylammonium monohydrochloride;Methanamine,N,N-dimethyl-,hydrochloride;HJ 1042-2019);TrimethylamineHcl99%
CBNumber:
CB8770378
Molecular Formula:
C3H10ClN
Molecular Weight:
95.57
MDL Number:
MFCD00012478
MOL File:
593-81-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
Trimethylamine hydrochloride 98% T72761 25g $25.6
Trimethylammonium chloride for synthesis 8.21178 5G $38.8
Trimethylammonium chloride for synthesis 8.21178 250g $128
Trimethylamine hydrochloride analytical standard 41284 100mg $95.6
Trimethylamine Hydrochloride >98.0%(N) T0465 100g $28
More product size

Trimethylamine hydrochloride Properties

Melting point 283-284 °C (dec.)(lit.)
Boiling point 132.32°C (rough estimate)
Density 0.9337 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index 1.4413 (estimate)
storage temp. Store below +30°C.
solubility SOLUBLE
form Crystalline Powder
color White to slightly cream
PH 5 (100g/l, H2O, 20℃)
Water Solubility SOLUBLE
Sensitive Hygroscopic
Merck 14,9710
BRN 3905063
Stability Hygroscopic
InChI 1S/C3H9N.ClH/c1-4(2)3;/h1-3H3;1H
InChIKey SZYJELPVAFJOGJ-UHFFFAOYSA-N
SMILES Cl[H].CN(C)C
LogP -2.25 at 25℃
CAS DataBase Reference 593-81-7(CAS DataBase Reference)
FDA UNII UW38SRM77K
NIST Chemistry Reference Methanamine,n,n-dimethyl-,hydrochloride(593-81-7)
EPA Substance Registry System Trimethylamine hydrochloride (593-81-7)
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38-38-36
Safety Statements  26-36-37/39
WGK Germany  1
RTECS  YH2700000
3-10
TSCA  TSCA listed
HS Code  29211190
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
Hazardous Substances Data 593-81-7(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 3090 mg/kg
NFPA 704
1
2 0

Trimethylamine hydrochloride price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T72761 Trimethylamine hydrochloride 98% 593-81-7 25g $25.6 2026-03-19 Buy
Sigma-Aldrich 8.21178 Trimethylammonium chloride for synthesis 593-81-7 5G $38.8 2026-03-19 Buy
Sigma-Aldrich 8.21178 Trimethylammonium chloride for synthesis 593-81-7 250g $128 2026-03-19 Buy
Sigma-Aldrich 41284 Trimethylamine hydrochloride analytical standard 593-81-7 100mg $95.6 2026-03-19 Buy
TCI Chemical T0465 Trimethylamine Hydrochloride >98.0%(N) 593-81-7 100g $28 2026-03-19 Buy
Product number Packaging Price Buy
T72761 25g $25.6 Buy
8.21178 5G $38.8 Buy
8.21178 250g $128 Buy
41284 100mg $95.6 Buy
T0465 100g $28 Buy

Trimethylamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

white to slightly cream crystalline powder

Uses

Trimethylamine hydrochloride is used in the manufacture of quaternary ammonium compounds, as insect attractant. It is also used as a raw material for the synthesis of choline chloride and ion exchange resins. Additionally, It acts as a cationic starch reagent, phase transfer catalyst, oil field chemicals, warning agent for natural gas and flotation agent.

Application

Trimethylamine hydrochloride(593-81-7) is a precursor to prepare aluminium chloride- trimethylamine hydrochloride ionic liquid, which is commonly used in electrodeposition of aluminum wires. It is also used in the synthesis of trimethylamine gallane, trimethylamine-borane and azido-bridged perovskite-type metal-organic frameworks (MOFs).

Definition

ChEBI: Trimethylamine hydrochloride is a hydrochloride salt formed by reaction of equimolar amounts of trimethylamine and hydrogen chloride. It contains a trimethylammonium.

Preparation

Trimethylamine hydrochloride can be synthesized through the reaction of trimethylamine (TMA) and hydrochloric acid (HCl). The synthesis reaction can be written as follows:
C3H9N+ HCl → C3H10ClN
The following steps are involved in obtaining trimethylamine hydrochloride:
Step 1: Evaporation of hydrochloric acid solution The hydrochloric acid solution is evaporated, first over a free flame, and later on a steam bath. This process results in concentration of the solution, which aids in the formation of trimethylamine hydrochloride crystals.
Step 2: Crystal formation and filtration As the solution becomes more and more concentrated, the trimethylamine hydrochloride crystals begin to form. The crystals are filtered periodically to remove them from the solution.
Step 3: Drying The filtered crystals are dried in an air bath for a few minutes, with a temperature range of 100-110°.
Step 4: Storage The air-dried crystals are then stored in a tightly closed bottle.
Step 5: Centrifugation (optional) If the trimethylamine hydrochloride crystals are centrifuged, the product is obtained pure and dry.
Overall, four runs yield an average of 710 g of pure trimethylamine hydrochloride and 82 g of slightly yellow-tinted product. This yield is equivalent to 89% of the theoretical amount based on ammonium chloride. The slight yellow coloration results from the evaporation of the last traces of solution.
DOI: 10.15227/orgsyn.001.0079

Flammability and Explosibility

Non flammable

Purification Methods

The salt crystallises from CHCl3, EtOH or n-propanol, and is dried under vacuum. It also crystallises from *benzene/MeOH, MeOH/diethyl ether and is dried under vacuum over paraffin wax and H2SO4. It is kept over P2O5 as it is hygroscopic.[Beilstein 4 H 262, 4 I 419, 4 IV 138.]

4637-24-5
593-81-7
Synthesis of Trimethylamine hydrochloride from N,N-Dimethylformamide dimethyl acetal
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View Lastest Price from Trimethylamine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Trimethylamine hydrochloride pictures 2026-04-30 Trimethylamine hydrochloride
593-81-7
US $10.00 / ASSAYS 1ASSAYS 99% 10 ton RongNa Biotechnology Co.,Ltd
Trimethylamine hydrochloride pictures 2026-04-30 Trimethylamine hydrochloride
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US $0.00-0.00 / G 1G 99% 1 ton/year Forest chemical technology
Trimethylamine hydrochloride pictures 2026-04-30 Trimethylamine hydrochloride
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US $100.00-75.00 / kg 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
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