IFLAB-BB F2108-0155
- CAS No.
- 95470-42-1
- Chemical Name:
- IFLAB-BB F2108-0155
- Synonyms
- IFLAB-BB F2108-0155;Ethyl 2-Bromo-4-methylimidazole-5-carboxylate;Ethyl 2-bromo-4-methyl-1H-imidazole-5-carboxylate;Ethyl 2-broMo-5-Methyl-4H-iMidazole-4-carboxylate;ethyl 2-broMo-5-Methyl-1H-iMidazole-4-carboxylate;2-Bromo-4-methyl-1H-imidazole-5-carboxylic acid ethyl ester;2-Bromo-5-methyl-4H-imidazole-4-carboxylic acid ethyl ester;2-BROMO-5-METHYL-1H-IMIDAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;2-BROMO-5-METHYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;1H-Imidazole-5-carboxylic acid,2-bromo-4-methyl-,ethyl ester
- CBNumber:
- CB8828095
- Molecular Formula:
- C7H9BrN2O2
- Molecular Weight:
- 233.06
- MDL Number:
- MFCD09033863
- MOL File:
- 95470-42-1.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
IFLAB-BB F2108-0155 price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 128216 | Ethyl2-bromo-4-methyl-1H-imidazole-5-carboxylate 97% | 95470-42-1 | 1g | $672 | 2021-12-16 | Buy |
| Matrix Scientific | 131730 | Ethyl2-bromo-5-methyl-1H-imidazole-4-carboxylate 97% | 95470-42-1 | 5g | $1008 | 2021-12-16 | Buy |
| Matrix Scientific | 131730 | Ethyl2-bromo-5-methyl-1H-imidazole-4-carboxylate 97% | 95470-42-1 | 25g | $3024 | 2021-12-16 | Buy |
| Ambeed | A315640 | Ethyl2-bromo-4-methyl-1H-imidazole-5-carboxylate 97% | 95470-42-1 | 25g | $1173 | 2021-12-16 | Buy |
| Alichem | 95470421 | Ethyl2-bromo-4-methyl-1H-imidazole-5-carboxylate | 95470-42-1 | 10g | $1333.78 | 2021-12-16 | Buy |
IFLAB-BB F2108-0155 Chemical Properties,Uses,Production
Synthesis
51605-32-4
95470-42-1
General procedure: The synthesis of ethyl 2-bromo-4-methyl-1H-imidazole-5-carboxylate (EV-AT8648-001) from ethyl 4-methyl-5-imidazolecarboxylate was performed as follows: Step 1: To a stirred solution of ethyl 4-methyl-1H-imidazole-5-carboxylate (CAS 51605-32-4, 500 mg, 3.24 mmol) in a mixture of acetonitrile (10 mL) and chloroform (10 mL), N-bromosuccinimide (577 mg, 3.24 mmol) was added. The reaction was carried out under nitrogen protection with stirring at room temperature for 18 hours. Upon completion of the reaction, the reaction mixture was concentrated and the residue was purified by fast column chromatography (eluent: 10-100% ethyl acetate/heptane gradient) to afford 560 mg (73% yield) of the target product, ethyl 2-bromo-4-methyl-1H-imidazole-5-carboxylate (EV-AT8648-001), as an off-white solid. LCMS analysis (Method D): retention time 0.87 min, mass spectrum m/z = 233/235 ([M+H]+).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 12, p. 3669 - 3674
[2] Patent: WO2017/147102, 2017, A1. Location in patent: Paragraph 00167-00168
[3] Patent: WO2008/111794, 2008, A1. Location in patent: Page/Page column 27
[4] Patent: US2009/156615, 2009, A1. Location in patent: Page/Page column 19
[5] Patent: US2015/284358, 2015, A1. Location in patent: Paragraph 0126; 0127; 0128
IFLAB-BB F2108-0155 Preparation Products And Raw materials
Raw materials
Preparation Products
IFLAB-BB F2108-0155 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
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| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
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| Acorn PharmaTech Co., Ltd. | 025-58395930 | sales@acornpharma.com | China | 982 | 60 |
| CEG Chemical Science&Technology Co., Ltd. | Mobile:13665161512 | China | 1785 | 58 | |
| Bide Pharmatech Ltd. | 400-164-7117 13681763483 | product02@bidepharm.com | China | 42446 | 60 |
