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ChemicalBook >> CAS DataBase List >>6-Chloro-2,3-diaminotoluene

6-Chloro-2,3-diaminotoluene

6-Chloro-2,3-diaminotoluene Structure
6-Chloro-2,3-diaminotoluene structure
CAS No.
673487-36-0
Chemical Name:
6-Chloro-2,3-diaminotoluene
Synonyms
4-Chloro-3-Methylbenzene-1,2-diaMine;6-CHLORO-2,3-DIAMINOTOLUENE;Phloroglucinol Impurity 241;4-Chloro-3-methyl-1,2-benzenediamine;1,2-Benzenediamine, 4-chloro-3-methyl-;Daridorexant Hydrochloride Impurity 127
CBNumber:
CB8837804
Molecular Formula:
C7H9ClN2
Molecular Weight:
156.61
MDL Number:
MFCD09026957
MOL File:
673487-36-0.mol
MSDS File:
SDS
Last updated:2026-05-28 06:17:29
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6-Chloro-2,3-diaminotoluene Properties

Melting point 46-47 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
Boiling point 305.6±37.0 °C(Predicted)
Density 1.281±0.06 g/cm3(Predicted)
storage temp. 2-8°C, protect from light
pka 3.65±0.10(Predicted)
Appearance Brown to reddish brown Solid
FDA UNII YJ4RCR5WCS

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

6-Chloro-2,3-diaminotoluene price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS39996 4-Chloro-3-methylbenzene-1,2-diamine 97% 673487-36-0 1g $124 2026-06-04 Buy
Activate Scientific AS39996 4-Chloro-3-methylbenzene-1,2-diamine 97% 673487-36-0 5g $369 2026-06-04 Buy
Matrix Scientific 134507 4-Chloro-3-methylbenzene-1,2-diamine 673487-36-0 250.00mg $37 2026-05-18 Buy
Matrix Scientific 134507 4-Chloro-3-methylbenzene-1,2-diamine 673487-36-0 1.00g $69 2026-05-18 Buy
Matrix Scientific 134507 4-Chloro-3-methylbenzene-1,2-diamine 673487-36-0 5.00g $223 2026-05-18 Buy
Product number Packaging Price Buy
AS39996 1g $124 Buy
AS39996 5g $369 Buy
134507 250.00mg $37 Buy
134507 1.00g $69 Buy
134507 5.00g $223 Buy

6-Chloro-2,3-diaminotoluene Chemical Properties,Uses,Production

Uses

6-Chloro-2,3-diaminotoluene is a white solid powder at room temperature and pressure, with significant alkalinity and strong nucleophilicity. Due to the presence of two amino units in the ortho position of the benzene ring, it can undergo condensation reactions with aldehydes to prepare corresponding benzimidazole derivatives. This reaction is widely used to prepare benzimidazole drugs and bioactive molecules. It is an intermediate in organic synthesis and medicinal chemistry, such as Nemonapride.

Synthesis

A solution of 3-chloro-2-methyl-6-nitroaniline in a mixture of acetic acid and water was heated to 90 C, to which iron powder was added. The resulting reaction mixture was further heated at 90 C for 2 hours. At the end of the reaction the reaction mixture was cooled to room temperature and poured into ice, then the pH was adjusted to 8 and ethyl acetate was added to the reaction mixture. The resulting mixture was filtered and the organic phase was separated, the resulting organic layer was dried with anhydrous sodium sulfate, filtered to remove the desiccant and the resulting filtrate was concentrated under vacuum. The resulting residue was purified by column chromatography on silica gel, eluting with pentane:ethyl acetate to give 6-chloro-2,3-diaminotoluene.

6-Chloro-2,3-diaminotoluene Preparation Products And Raw materials

Raw materials

Preparation Products

6-Chloro-2,3-diaminotoluene Suppliers

Global( 96)Suppliers
Supplier Tel Email Country ProdList Advantage
Tianjin and Sinde Biotechnology Co., Ltd. 15022315965; 18502259037 sales_hxd@163.com China 385 58
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai yirong biology science and technology co., ltd 18049974220 3060526242@qq.com China 999 60
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Jinan LuoHe PharmaTech Co., Ltd. 86-0531-68658065 15726150375 1071018499@qq.com China 525 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Shanghai Changyan Chem & Tech Co., Ltd. 021-20242659 18930833303 sales@changyanchem.cn China 4998 55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291 tcy@tcypharm.com China 8696 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9995 55
Supplier Advantage
Tianjin and Sinde Biotechnology Co., Ltd. 58
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai yirong biology science and technology co., ltd 60
Bide Pharmatech Ltd. 60
Jinan LuoHe PharmaTech Co., Ltd. 58
Shanghai Kewel Chemical Co., Ltd. 50
Shanghai Changyan Chem & Tech Co., Ltd. 55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 58
Amadis Chemical Company Limited 58
Hubei Yangxin Medical Technology Co., Ltd. 55

View Lastest Price from 6-Chloro-2,3-diaminotoluene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Chloro-2,3-diaminotoluene pictures 2026-06-30 6-Chloro-2,3-diaminotoluene
673487-36-0
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
Daridorexant Impurity pictures 2025-12-16 Daridorexant Impurity
673487-36-0
 10mg 99%+ HPLC 1000 Moxin Chemicals
4-Chloro-3-methylbenzene-1,2-diamine pictures 2025-11-19 4-Chloro-3-methylbenzene-1,2-diamine
673487-36-0
 1kg 98% 1000kg Shanghai Joiny Pharmaceutical Co.,LTD

6-Chloro-2,3-diaminotoluene Spectrum

6-Chloro-2,3-diaminotoluene(673487-36-0)1HNMR

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6-CHLORO-2,3-DIAMINOTOLUENE 1,2-Benzenediamine, 4-chloro-3-methyl- Phloroglucinol Impurity 241 4-Chloro-3-Methylbenzene-1,2-diaMine Daridorexant Hydrochloride Impurity 127 4-Chloro-3-methyl-1,2-benzenediamine 673487-36-0