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4-Methylumbelliferyl-beta-D-glucopyranoside

4-Methylumbelliferyl-beta-D-glucopyranoside structure

CAS No.: 18997-57-4

Chemical Name:: 4-Methylumbelliferyl-beta-D-glucopyranoside

Synonyms: 4-METHYLUMBELLIFERYL BETA-D-GLUCOSIDE;4-Methylumbelliferyl β-D-glucopyranoside;MUD;MUG;MU-Glu;MUGGAL;MU-GAL;7-(B2;4-MU-GLU;GLC1-B-4MU

CBNumber:: CB8853266

Molecular Formula:: C16H18O8

Molecular Weight:: 338.31

MDL Number:: MFCD00063694

MOL File:: 18997-57-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-14 16:49:18

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4-Methylumbelliferyl-beta-D-glucopyranoside Properties

Melting point	258-263 °C (dec.)
Boiling point	394.46°C (rough estimate)
Density	1.522
refractive index	1.4430 (estimate)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	DMF: 5 mg/ml; DMSO: 50 mg/ml
pka	12.73±0.70(Predicted)
form	Powder
color	White to off-white
Water Solubility	Soluble in DMF or water
λmax	320nm(Buffer)(lit.)
BRN	94672
InChI	InChI=1/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13+,14+,15-,16-/s3
InChIKey	YUDPTGPSBJVHCN-ZDHZLMEDNA-N
SMILES	C12OC(C=C(C)C=1C=CC(O[C@H]1[C@H](O)[C@H]([C@@H](O)[C@@H](CO)O1)O)=C2)=O \|&1:11,12,14,15,17,r\|
CAS DataBase Reference	18997-57-4(CAS DataBase Reference)
UNSPSC Code	12352204
NACRES	NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes	T+
Risk Statements	26/27/28
Safety Statements	22-24/25
WGK Germany	3
F	3-10-21
HS Code	29389090

4-Methylumbelliferyl-beta-D-glucopyranoside price More Price(65)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M3633	4-Methylumbelliferyl β-D-glucopyranoside β-glucosidase substrate	18997-57-4	1g	$535	2026-04-30	Buy
Sigma-Aldrich	M3633	4-Methylumbelliferyl β-D-glucopyranoside β-glucosidase substrate	18997-57-4	5g	$2060	2026-04-30	Buy
TCI Chemical	M3022	4-Methylumbelliferyl β-D-Glucopyranoside >98.0%(HPLC)	18997-57-4	250mg	$24	2026-04-30	Buy
TCI Chemical	M3022	4-Methylumbelliferyl β-D-Glucopyranoside >98.0%(HPLC)	18997-57-4	1g	$66	2026-04-30	Buy
Cayman Chemical	20948	4-Methylumbelliferyl-β-D-Glucopyranoside ≥98%	18997-57-4	250mg	$36	2026-04-30	Buy

Product number	Packaging	Price	Buy
M3633	1g	$535	Buy
M3633	5g	$2060	Buy
M3022	250mg	$24	Buy
M3022	1g	$66	Buy
20948	250mg	$36	Buy

4-Methylumbelliferyl-beta-D-glucopyranoside Chemical Properties, Uses, Production

Description

4-Methylumbelliferyl-β-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of β-glucosidase and β-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel β-glucosidases, 4-MUG is used in assays to evaluate deficiency in β- glucocerebrosidase activity related to Gaucher disease. Hydrolysis of 4-MUG releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.

Chemical Properties

White Powder

Uses

4-Methylumbelliferyl β-D-glucopyranoside has been used as substrate:

in glucosylceramidase β enzyme activity assay in lysosome-enriched fractions from primary hippocampal neurons
in β-glucosidase assay during yeast fermentation
to assay glucocerebrosidase 1 (GBA1)-related glucosidase activity in macrophage cell line (RAW)

Uses

A fluorogenic substrate in the assay of -glucosidase.Fluorescence: max. Abs. 316nm; max. Em. 372nm; e x 10-3: 15

Uses

A fluorogenic substrate in the assay of -glucosidase. Fluorescence: max. Abs. 316nm; max. Em. 372nm; e x 10-3: 15

Definition

ChEBI: A beta-D-glucoside having a 4-methylumbelliferyl substituent at the anomeric position.

Biochem/physiol Actions

4-Methylumbelliferyl β-D-glucopyranoside is a synthetic enzymatic substrate for glycosidase. It has been used as substrate for the β- glucosidase from enterococci.

Purification Methods

4-Methylumbellifer-7-yl--Dglucopyranoside crystallises as the half hydrate from hot H2O. [Constantzas & Kocourek Collect Czech Chem Commun 24 1099 1959, De Re et al. Ann Chim (Rome) 4 9 2089 1959, Courtin-Duchateau & Veyrière Carbohydr Research 65 23, 29 1978, Beilstein 18 III/IV 5152, 8 IV 433, 18/7 V 616.]

References

[1] ALICIA HERNáNDEZ-GUZMáN. Purification and characterization of an extracellular β-glucosidase from Sporothrix schenckii[J]. FEBS Open Bio, 2016, 6 11: 1067-1077. DOI: 10.1002/2211-5463.12108
[2] RADOSAW KWAPISZEWSKI. A microfluidic device with fluorimetric detection for intracellular components analysis[J]. Biomedical Microdevices, 2011, 13 3: 431-440. DOI: 10.1007/s10544-011-9511-0
[3] MEERA SHANMUGANATHAN Philip B M. Inhibitor screening of pharmacological chaperones for lysosomal β-glucocerebrosidase by capillary electrophoresis[J]. Analytical and Bioanalytical Chemistry, 2011, 399 8: 2843-2853. DOI: 10.1007/s00216-011-4671-6

4-Methylumbelliferyl-beta-D-glucopyranoside Preparation Products And Raw materials

Raw materials

Preparation Products

4’-Methylumbelliferyl 2,3,4,-Tri-O-acetyl-6-O-trityl-β-D-glucopyranoside

4-Methylumbelliferyl-beta-D-glucopyranoside Suppliers

Global Suppliers ( 299)

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Samuel Pharmaceutical Co., Ltd.	0531-88821801 15192360884	605818151@qq.com	China	479	58
Jinan Shangbo Pharmaceutical Co., Ltd.	18253163690	yinxiuyang@shengquan.com	China	63	58
Linyi Californium Information Technology Co., Ltd.	13188735557	693256217@qq.com	China	212	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Feiyang Biotechnology Co., Ltd	0533-7866336 13573361699	sales@chemfy.com	China	524	62

Supplier	Advantage
Jinan Samuel Pharmaceutical Co., Ltd.	58
Jinan Shangbo Pharmaceutical Co., Ltd.	58
Linyi Californium Information Technology Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
INTATRADE GmbH	66
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Beijing HwrkChemical Technology Co., Ltd	55
Beijing Ouhe Technology Co., Ltd	60
Feiyang Biotechnology Co., Ltd	62

View Latest Price from 4-Methylumbelliferyl-beta-D-glucopyranoside manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-18	4-Methylumbelliferyl-beta-D-glucopyranoside 18997-57-4		10G	98%min	30kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-07-14	4-Methylumbelliferyl-β-D-Glucopyranoside 18997-57-4			99.89%	10g	TargetMol Chemicals Inc.
2021-07-02	4-Methylumbelliferyl-beta-D-glucopyranoside 18997-57-4	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

4-Methylumbelliferyl-beta-D-glucopyranoside
18997-57-4
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

4-Methylumbelliferyl-β-D-Glucopyranoside
18997-57-4
$0.00
99.89%
TargetMol Chemicals Inc.

4-Methylumbelliferyl-beta-D-glucopyranoside
18997-57-4
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

4-Methylumbelliferyl-beta-D-glucopyranoside Spectrum

4-Methylumbelliferyl-beta-D-glucopyranoside(18997-57-4)¹HNMR

18997-57-4 (4-Methylumbelliferyl-beta-D-glucopyranoside) Related Search:

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4-METHYLUMBELLIFERYL-BETA-D-GLUCO-PYRANOSIDE FOR FLUORESCENCE 99+% 4-METHYLUMBELLIFERYL BETA-D-GLUCOSIDE CRYSTALLINE 4-METHYLUMBELLIFERYL-b-D-GLUCOPYRANOSIDE extrapure 4-methylumberiferryl-beta-D-glucopyranoside 4-Methylumbelliferryl-β-D-glucoside 7-(β-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one 7-(β-D-Glucopyranosyloxy)-4-methylcoumarin 4-Methylumbelliferyl-beta-D-glucopyranoside,99% 4-Methylumbellifery-β-D-glucopyranoside 4-Methylumbelliferyl β-D-glucopyranoside ,98% MU-Glu 3-MethyluMbelliferyl β-D-glucopyranoside 4-MethyluMbelliferyl-beta-D-glucopyranoside, 99% 500MG 4-MethyluMbelliferyl Glucopyranoside 4-Methylumbelliferyl β-D-glucopyranosid 4-Methylumbelliferyl-beta-D-glucoside *CAS 18997-57-4* 4-Methylumbelliferyl β-D-glucopyranoside,MUD 4-Methyl-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one 4-methyl-7-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-2-one 4-methylumbelliferylglucoside 7-(beta-d-glucopyranosyloxy)-4-methyl-2h-1-benzopyran-2-on MUD MUGGAL MUGLUCOSIDE MUG MU-GAL MUGALACTOSIDE METHYLUMBELLIFERYL-B-D-GALACTOPYRANOSIDE, 4- METHYLUMBELLIFERYL-B-D-GLUCOPYRANOSIDE, 4- GLC1-B-4MU 4-METHYLUMBELLIFERYL B-D-GALACTOPYRANOSIDE 4-METHYLUMBELLIFERYL-B-D-GALACTOSIDE 4-MU-BETA-D-GLC 4-MU-BETA-D-GAL 7-HYDROXY-4-METHYLCUMARIN-BETA-D-GALACTOPYRANOSID 7-HYDROXY-4-METHYLCUMARIN-BETA-D-GLUCOPYRANOSID 4-METHYLUMBELLIFERYL-B-D-GLUCOPYRANOSIDE 4-METHYLUMBELLIFERYL-B-D-GLUCOSIDE 4'-METHYLUMBELLIFERYL-BETA-D-GLUCOPYRANOSIDE 4-METHYLUMBELLIFERYL-BETA-D-GLUCOPYRANOSIDE 3-Methylumbelliferyl 7-(beta-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one 4-METHYLUMBELLIFERYL-SS-D-GLUCOPYRANOSIDE 2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-4-methyl- 4-Methylumbelliferyl-beta-D-glucopyranoside USP/EP/BP 4-Methylumbelliferyl β-D-Glucoside 7-(B2 -D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one 4-Methylumbelliferyl-β-D- Glucopyranoside extrapure 2H-1-Benzopyran-2-one,7-(b-D-glucopyranosyloxy)-4-methyl- 4-MU-GLU 4-MU-β-Gluc fluorogenic,substrate,4 Methylumbelliferyl β D Glucopyranoside,Inhibitor,chromogenic,4MethylumbelliferylβDGlucopyranoside,inhibit,4-methylumbelliferyl,fluorescent 4-Methylumbelliferone- β- D-glucoside MU-GLU, Fluorogenic beta-glucosidase substrate 4-Methylumbelliferyl β-D-glucopyranoside 7-(β-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one 4-methyloneacyl-Β-D-pyransacharideacidglycoside