ChemicalBook >> CAS DataBase List >>Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)-

Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)-

CAS No.
465-90-7
Chemical Name:
Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)-
Synonyms
Hellebrigenin;3β,5,14-Trihydroxy-19-oxo-5β-bufa-20,22-dienolide;19-Oxo-3β,5,14-trihydroxy-5β-bufa-20,22-dienolide;Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3β,5β)-;Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)-;(3S,5S,10S,13R,14S,17R)-3,5,14-Trihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
CBNumber:
CB8876405
Molecular Formula:
C24H32O6
Molecular Weight:
416.50728
MDL Number:
MFCD01740826
MOL File:
465-90-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:42
Product description Number Pack Size Price
Bufotalidin AAA46590 50mg $920.5
Bufotalidin AAA46590 100mg $1473
Hellebrigenin 99.69% CS-0034272 5mg $347
Hellebrigenin BA3182 1mg $112
Hellebrigenin BA3182 5mg $288

Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- Properties

Melting point 175 °C(Solv: ethanol (64-17-5))
Boiling point 626.3±55.0 °C(Predicted)
Density 1.419±0.06 g/cm3(Predicted)
storage temp. 4°C, away from moisture and light
form Solid
pka 13.94±0.70(Predicted)
color White to off-white

Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth AAA46590 Bufotalidin 465-90-7 50mg $920.5 2026-06-04 Buy
Biosynth AAA46590 Bufotalidin 465-90-7 100mg $1473 2026-06-04 Buy
ChemScene CS-0034272 Hellebrigenin 99.69% 465-90-7 5mg $347 2026-06-04 Buy
ApexBio Technology BA3182 Hellebrigenin 465-90-7 1mg $112 2026-05-06 Buy
ApexBio Technology BA3182 Hellebrigenin 465-90-7 5mg $288 2026-05-06 Buy
Product number Packaging Price Buy
AAA46590 50mg $920.5 Buy
AAA46590 100mg $1473 Buy
CS-0034272 5mg $347 Buy
BA3182 1mg $112 Buy
BA3182 5mg $288 Buy

Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- Chemical Properties,Uses,Production

Uses

Hellebrigenin, one of bufadienolides belonging to cardioactive steroids, is isolated from traditional Chinese medicine Venenum Bufonis. Hellebrigenin induces DNA damage and cell cycle G2/M arrest. Hellebrigenin triggers mitochondria-mediated apoptosis.

References

[1] Deng LJ, et al. Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Chem Biol Interact. 2014 Aug 5;219:184-94. DOI:10.1016/j.cbi.2014.06.003

Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- Preparation Products And Raw materials

Raw materials

Preparation Products

Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- Suppliers

Global( 51)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +86-18080483897 sales@biopurify.com China 4616 58
career henan chemical co
+86-0371-86658258 factory@coreychem.com China 29780 58
Hefei Hangang Pharmaceutical Technology Co., Ltd.
+8618062405514 ada@ipurechemical.com China 10224 58
BOC Sciences
16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 38999 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11674 58
Aladdin Scientific
tp@aladdinsci.com United States 50108 58
Mensura Group Limited
18780014153 1058503172@qq.com China 2900 58
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3984 66
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56

View Lastest Price from Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- pictures 2020-02-18 Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)-
465-90-7
$8.00 1KG >98% HPLC 20 tons Career Henan Chemical Co

Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- Spectrum

Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- 19-Oxo-3β,5,14-trihydroxy-5β-bufa-20,22-dienolide 3β,5,14-Trihydroxy-19-oxo-5β-bufa-20,22-dienolide (3S,5S,10S,13R,14S,17R)-3,5,14-Trihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3β,5β)- Hellebrigenin 465-90-7