3-(4-fluorophenyl)glutaric acid
- CAS No.
- 3449-63-6
- Chemical Name:
- 3-(4-fluorophenyl)glutaric acid
- Synonyms
- 3-(4-Fluorophenyl)pentanedioic acid;3-(4-fluorophenyl)glutaric acid;Pentanedioic acid, 3-(4-fluorophenyl)-;3-(4-fluorophenyl)pentan-1,5-dioic acid
- CBNumber:
- CB8907642
- Molecular Formula:
- C11H11FO4
- Molecular Weight:
- 226.2
- MDL Number:
- MFCD19352347
- MOL File:
- 3449-63-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P260-P280-P271 |
| HS Code | 2918199890 |
3-(4-fluorophenyl)glutaric acid price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC48529 | 3-(4-Fluorophenyl)pentanedioic acid 95% | 3449-63-6 | 100mg | $25 | 2026-06-04 | Buy |
| Apolloscientific | PC48529 | 3-(4-Fluorophenyl)pentanedioic acid 95% | 3449-63-6 | 250mg | $41 | 2026-06-04 | Buy |
| Activate Scientific | AS36553 | 3-(4-Fluorophenyl)pentanedioic acid 95% | 3449-63-6 | 1g | $184 | 2026-06-04 | Buy |
| Activate Scientific | AS36553 | 3-(4-Fluorophenyl)pentanedioic acid 95% | 3449-63-6 | 5g | $592 | 2026-06-04 | Buy |
| Synthonix | F54472 | 3-(4-Fluorophenyl)pentanedioic acid 95+% | 3449-63-6 | 100mg | $80 | 2026-05-06 | Buy |
3-(4-fluorophenyl)glutaric acid Chemical Properties,Uses,Production
Synthesis
349446-90-8
3449-63-6
2-(4-Fluorophenyl)-1,1,3-trimethoxycarbonylpropane (6.7 g, 21.5 mmol) was used as starting material and dissolved in methanol (100 ml). To this solution, aqueous sodium hydroxide solution (3N, 23 ml, 69 mmol) was slowly added at room temperature. The reaction mixture was stirred for 12 hours. After completion of the reaction, most of the solvent was removed by concentration under reduced pressure. Subsequently, water (20 ml) and concentrated hydrochloric acid (10 ml) were added to the concentrate and the mixture was heated to reflux under ice bath cooling. After cooling, the reaction mixture was extracted with ethyl acetate. The organic phases were combined and washed sequentially with water and saturated sodium chloride solution and then dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure to give the crude product. The crude product was purified by crystallization from ethyl acetate and washed with hexane to give finally 3-(4-fluorophenyl)glutaric acid (4.5 g, 93% yield) with a melting point of 145-147 °C. 1H-NMR (DMSO-d6) δ: 2.48 (2H, dd, J = 15.8,8.8 Hz), 2.64 (2H, dd, J = 15.8,6.2 Hz). 3.20-3.56 (1H, m), 7.00-7.20 (2H, m), 7.22-7.40 (2H, m), 12.1 (2H, br s).
References
[1] Patent: EP1411052, 2004, A1. Location in patent: Page 53-54
[2] Tetrahedron Asymmetry, 2001, vol. 12, # 3, p. 419 - 426
3-(4-fluorophenyl)glutaric acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-(4-fluorophenyl)glutaric acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Tongxin Bio-Tech Co., Ltd | 0523-86818997 18652728585 | sales@allyrise.com | China | 2986 | 60 |
| Chengdu Firster Pharmaceutical Co., Ltd. | 028-87078428 028-87074958 | chengzhenyong@cdfirster.com | China | 2580 | 60 |
| NovoChemy Ltd. | 86-(0)21-31261262 373522135 | sales@novochemy.com | China | 6491 | 58 |
| Suzhou Crst Pharmatech Co., Ltd. | 0512-62910395 17751098781 | sales@crstpharma.com | China | 497 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Hangzhou Molcore Biopharmatech Co.,Ltd | 400-711-5280 86-571-81025280 | sales@molcore.com | China | 9957 | 58 |
| Aikon International Limited | 025-66113011 19370895928 | qzhang@aikonchem.com | China | 15390 | 58 |
| Changzhou Liren Medical Technology Co. Ltd. | 0519-85859058 13915836899 | 2078957504@qq.com | China | 454 | 58 |
| Aishilun biotechnology (Shanghai) co., LTD | 021-50676523 18019098996 | info@acelybio.com | China | 3950 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
View Lastest Price from 3-(4-fluorophenyl)glutaric acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-07-25 | 3-(4-fluorophenyl)glutaric acid
3449-63-6
|
$1.00 | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd |
-
- 3-(4-fluorophenyl)glutaric acid
3449-63-6
- $1.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
