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4-isobutyloxazolidine-2,5-dione

CAS No.
51248-35-2
Chemical Name:
4-isobutyloxazolidine-2,5-dione
Synonyms
DL-leucine NCA;ILE-NCA;H-DL-Leu-NCA;Einecs 257-083-3;Isobutyloxazolidine-2,5-dione;4-isobutyloxazolidine-2,5-dione;4-(2-Methylpropyl)-2,5-oxazolidinedione;4-(2-methylpropyl)oxazolidine-2,5-dione;2,5-Oxazolidinedione, 4-(2-methylpropyl)-;Isobutyloxazolidine-2,5-dione[H-DL-Leu-NCA
CBNumber:
CB8909732
Molecular Formula:
C7H11NO3
Molecular Weight:
157.17
MDL Number:
MFCD02684167
MOL File:
51248-35-2.mol
MSDS File:
SDS
Last updated:2026-05-28 04:53:24

4-isobutyloxazolidine-2,5-dione Properties

Melting point 47-48 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4))
Density 1.124±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 9.38±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2934999090

4-isobutyloxazolidine-2,5-dione price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR470083 4-Isobutyloxazolidine-2,5-dione 97% 51248-35-2 250mg $25 2026-06-04 Buy
Apolloscientific OR470083 4-Isobutyloxazolidine-2,5-dione 97% 51248-35-2 1g $30 2026-06-04 Buy
Apolloscientific OR470083 4-Isobutyloxazolidine-2,5-dione 97% 51248-35-2 5g $71 2026-06-04 Buy
Apolloscientific OR470083 4-Isobutyloxazolidine-2,5-dione 97% 51248-35-2 25g $312 2026-06-04 Buy
Synthonix B43775 Isobutyloxazolidine-2,5-dione 97+% 51248-35-2 250mg $24 2026-05-06 Buy
Product number Packaging Price Buy
OR470083 250mg $25 Buy
OR470083 1g $30 Buy
OR470083 5g $71 Buy
OR470083 25g $312 Buy
B43775 250mg $24 Buy

4-isobutyloxazolidine-2,5-dione Chemical Properties, Uses, Production

Preparation

A solution of phosgene(12.5% in toluene, 25 mL, 31.6 mmol) was added to a suspension of l-leucine (1.31 g, 10 mmol) in dioxane (30 mL) and ethyl acetate (25 mL) at 40 ℃ under a static atmosphere of nitrogen. After 4 h, the leucine had dissolved and then the excess phosgene was removed in a stream of nitrogen. The solvent was removed at 40 ℃ in vacuo and the residue was recrystallized from diethyl ether/light petroleum (bp 40–60 ℃) to yield colorless needles of 4-(2-methylpropyl)oxazolidine-2,5-dione (1.01 g, 69%).

32315-10-9
328-39-2
51248-35-2
Synthesis of 4-isobutyloxazolidine-2,5-dione from Triphosgene and DL-Leucine

4-isobutyloxazolidine-2,5-dione Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 41)
Supplier Tel Email Country ProdList Advantage
Shanghai civi chemical technology co.,Ltd 86-21-34053660 sale@labgogo.com China 9853 52
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Balmxy Pharmaceutical Co., Ltd 021-24206007 13764915196 sales@balmxy.com China 6959 55
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 1999 58
Accela ChemBio Inc. +1(858) 699-3322 marketing@accelachem.com United States 6022 65
ShangHai Movin Pharmaceutical Co., Ltd. 13681854265 info@moenpharm.com China 488 55
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 info@qiaochem.com China 6065 65
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Sichuan jiayinglai technology CO.,LTD 9018 15982359653 1394531348@qq.com China 2271 55
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58

View Latest Price from 4-isobutyloxazolidine-2,5-dione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ile-NCA pictures 2026-09-14 Ile-NCA
51248-35-2
1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
  • Ile-NCA pictures
  • Ile-NCA
    51248-35-2
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
4-isobutyloxazolidine-2,5-dione Einecs 257-083-3 NCA of N-carboxyanhydride of raceMic DL-leucine 4-(2-Methylpropyl)-2,5-oxazolidinedione ILE-NCA H-DL-Leu-NCA 4-(2-methylpropyl)oxazolidine-2,5-dione Isobutyloxazolidine-2,5-dione 2,5-Oxazolidinedione, 4-(2-methylpropyl)- Isobutyloxazolidine-2,5-dione[H-DL-Leu-NCA DL-leucine NCA 51248-35-2