3beta,14,16beta-trihydroxy-5-betacard-20(22)-enolide 16-acetate
- CAS No.
- 465-15-6
- Chemical Name:
- 3beta,14,16beta-trihydroxy-5-betacard-20(22)-enolide 16-acetate
- Synonyms
- oleandrigenin;0leandrigenin;Oleandrisenin;16β-Acetoxy-3β,14-dihydroxy-5β-card-20(22)-enolide;16β-Acetyloxy-3β,14-dihydroxy-5β-card-20(22)-enolide;16β-Acetoxy-3β,14-dihydroxy-5β,14β-carda-20(22)-enolide;3beta,14,16beta-trihydroxy-5-betacard-20(22)-enolide 16-acetate;Card-20(22)-enolide, 16-(acetyloxy)-3,14-dihydroxy-, (3β,5β,16β)-;(3S,5R,8R,9S,10S,13R,14S,16S,17R)-3,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl acetate
- CBNumber:
- CB8929824
- Molecular Formula:
- C25H36O6
- Molecular Weight:
- 432.55
- MDL Number:
- MOL File:
- 465-15-6.mol
- MSDS File:
- SDS
| Melting point | 223 °C |
|---|---|
| Boiling point | 584.6±50.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| pka | 14.35±0.70(Predicted) |
| InChIKey | IWCNCUVTGOMGKG-LXDPVJNCNA-N |
| SMILES | [C@@H]1(O)C[C@]2([H])[C@](C)(CC1)[C@]1([H])[C@]([H])(C3(O)[C@@](CC1)(C)[C@@H](C1=CC(=O)OC1)[C@@H](OC(=O)C)C3)CC2 |&1:0,3,5,9,11,15,19,26,r| |
| FDA UNII | GQ25UYW4QV |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
3beta,14,16beta-trihydroxy-5-betacard-20(22)-enolide 16-acetate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0695163 | Oleandrigenin 98.42% | 465-15-6 | 1mg | $433 | 2026-06-04 | Buy |
| ChemScene | CS-0695163 | Oleandrigenin 98.42% | 465-15-6 | 5mg | $867 | 2026-06-04 | Buy |
| Arctom | HY-N11690 | Oleandrigenin 98.42% | 465-15-6 | 1mg | $380 | 2026-05-26 | Buy |
| Arctom | HY-N11690 | Oleandrigenin 98.42% | 465-15-6 | 5mg | $760 | 2026-05-26 | Buy |
3beta,14,16beta-trihydroxy-5-betacard-20(22)-enolide 16-acetate Chemical Properties, Uses, Production
Uses
Oleandrigenin is a potent cardiotonic steroid. Oleandrigenin shows Na+/K+-ATP-ase inhibiting and cytotoxic activities[1][2].
Definition
ChEBI: A steroid ester that is the 16-acetyl derivative of gitoxigenin.
References
[1] Fejedelem Z, et al. Synthesis of Cardiotonic Steroids Oleandrigenin and Rhodexin B. J Org Chem. 2021 Aug 6;86(15):10249-10262. DOI:10.1021/acs.joc.1c00985
[2] Michalak K, et al. Synthesis and evaluation of Na+/K+-ATP-ase inhibiting and cytotoxic in vitro activities of oleandrigenin and its selected 17β-(butenolidyl)- and 17β-(3-furyl)- analogues. Eur J Med Chem. 2020 Sep 15;202:112520. DOI:10.1016/j.ejmech.2020.112520
3beta,14,16beta-trihydroxy-5-betacard-20(22)-enolide 16-acetate Preparation Products And Raw materials
Raw materials
Preparation Products
3beta,14,16beta-trihydroxy-5-betacard-20(22)-enolide 16-acetate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Huzhou ZhanShu Biotechnology Co.,Ltd | 0572-8889530 18167260939 | zsubio@163.com | China | 412 | 58 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 18108052721 | 2850505130@qq.com | China | 5037 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| ChengDu YiRui Bio-Technology CO., LTD | 18224028459 18224028459 | yirui307@163.com | China | 996 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Shanghai Taopu Industrial Co., LTD | 15900573766 18018507602 | 3165608826@qq.com | China | 4406 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-029-81148696 18161915376 | 1027@dideu.com | China | 9989 | 58 |
| Shanghai Moqi Biological Technology Co., LTD | 13341702378 | 190129269@qq.com | China | 10000 | 58 |
