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4-Chlorothiazole-5-carboxaldehyde

4-Chlorothiazole-5-carboxaldehyde Structure
4-Chlorothiazole-5-carboxaldehyde structure
CAS No.
104146-17-0
Chemical Name:
4-Chlorothiazole-5-carboxaldehyde
Synonyms
4-Chlorothiazole-5-carbaldehyde;4-chloro-5-thiazolecarboxaldehyde;4-Chlorothiazole-5-carboxaldehyde;5-Thiazolecarboxaldehyde, 4-chloro-;4-chloro-1,3-thiazole-5-carbaldehyde;4-Chlorothiazole-5-carboxaldehyde?New;5-Thiazolecarboxaldehyde, 4-chloro- (9CI)
CBNumber:
CB8967473
Molecular Formula:
C4H2ClNOS
Molecular Weight:
147.58
MDL Number:
MFCD09837291
MOL File:
104146-17-0.mol
MSDS File:
SDS
Last updated:2026-05-28 04:33:52
Product description Number Pack Size Price
4-Chlorothiazole-5-carboxaldehyde 97% AS31028 1g $72
4-Chlorothiazole-5-carboxaldehyde 97% AS31028 5g $342
4-Chlorothiazole-5-carbaldehyde 309481 1.00g $65
4-Chlorothiazole-5-carbaldehyde 309481 5.00g $252
4-Chlorothiazole-5-carbaldehyde 309481 10.00g $444
More product size
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4-Chlorothiazole-5-carboxaldehyde Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
Appearance Light yellow to yellow Solid
InChI InChI=1S/C4H2ClNOS/c5-4-3(1-7)8-2-6-4/h1-2H
InChIKey GJTWEAFBOIYNLZ-UHFFFAOYSA-N
SMILES S1C(C=O)=C(Cl)N=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H302-H332-H335-H319-H312
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2934999090

4-Chlorothiazole-5-carboxaldehyde price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS31028 4-Chlorothiazole-5-carboxaldehyde 97% 104146-17-0 1g $72 2026-06-04 Buy
Activate Scientific AS31028 4-Chlorothiazole-5-carboxaldehyde 97% 104146-17-0 5g $342 2026-06-04 Buy
Matrix Scientific 309481 4-Chlorothiazole-5-carbaldehyde 104146-17-0 1.00g $65 2026-05-19 Buy
Matrix Scientific 309481 4-Chlorothiazole-5-carbaldehyde 104146-17-0 5.00g $252 2026-05-19 Buy
Matrix Scientific 309481 4-Chlorothiazole-5-carbaldehyde 104146-17-0 10.00g $444 2026-05-19 Buy
Product number Packaging Price Buy
AS31028 1g $72 Buy
AS31028 5g $342 Buy
309481 1.00g $65 Buy
309481 5.00g $252 Buy
309481 10.00g $444 Buy

4-Chlorothiazole-5-carboxaldehyde Chemical Properties,Uses,Production

Synthesis

Thiazole, 4-chloro-5-(1,3-dioxolan-2-yl)-

478489-73-5

4-Chlorothiazole-5-carboxaldehyde

104146-17-0

General procedure for the synthesis of 4-chlorothiazole-5-carbaldehyde (333): to a stirred solution of 4-chloro-5-(1,3-dioxolan-2-yl)thiazole (332, 1.1 g, 5.75 mmol) in THF (10 mL) was slowly added an aqueous 5N HCl solution (6 mL) at 0°C. The reaction mixture was gradually warmed up to room temperature and stirred continuously for 3 hours. The reaction progress was monitored by TLC. After completion of the reaction, the mixture was poured into brine (20 mL) and extracted with EtOAc (2 x 50 mL). The organic phases were combined, washed with saturated sodium bicarbonate solution (100 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford the target product 4-chlorothiazole-5-carbaldehyde (333, 800 mg, 95%) as a yellow oil.TLC conditions: 10% EtOAc/hexanes (Rf=0.3); 1H NMR (CDCl3, 500 MHz): δ 10.11 (s, 1H), 9.00 (s, 1H).

References

[1] Patent: WO2015/138895, 2015, A1. Location in patent: Paragraph 000273
[2] Patent: US2010/298334, 2010, A1. Location in patent: Page/Page column 78
[3] Patent: WO2005/92885, 2005, A1. Location in patent: Page/Page column 94
[4] Patent: US2003/45546, 2003, A1
[5] Patent: WO2010/132999, 2010, A1. Location in patent: Page/Page column 148

4-Chlorothiazole-5-carboxaldehyde Preparation Products And Raw materials

Raw materials

Thiazole, 4-chloro-5-(1,3-dioxolan-2-yl)- Tetrahydrofuran Hydrochloric acid 1,4-Dioxane Water

Preparation Products

4-Chlorothiazole-5-carboxaldehyde Suppliers

Global( 92)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 9976 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Suzhou ARTK Medchem Co., Ltd. 		+8618118463618 sales1@artkmedchem.com China 39021 58
Shanghai Hanhong Scientific Co., Ltd. 		+undefined17612118332 Lucky@hanhonggroup.com China 5844 58
NANJING YINGWEN BIOTECHNOLOGY CO LTD 		+8613382787392 sales@aeechem.com China 10002 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Fuxin Pharmaceutical 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Labnetwork lnc. 		58
Aladdin Scientific 		58
Suzhou ARTK Medchem Co., Ltd. 		58
Shanghai Hanhong Scientific Co., Ltd. 		58
NANJING YINGWEN BIOTECHNOLOGY CO LTD 		58

4-Chlorothiazole-5-carboxaldehyde Spectrum

4-Chlorothiazole-5-carboxaldehyde(104146-17-0)1HNMR

104146-17-0(4-Chlorothiazole-5-carboxaldehyde)Related Search:

4-CHLORO-2-(1-METHYL-4-PIPERAZINYL)-5-THIAZOLECARBOXALDEHYDE 2-AMINO-4-CHLORO-5-THIAZOLECARBALDEHYDE 2,4-Dichloro-5-thiazolecarboxaldehyde 4-Chlorothiazole 4-CHLORO-2-PHENYLAMINO-THIAZOLE-5-CARBALDEHYDE
2-(4-ACETYLPIPERAZIN-1-YL)-4-CHLOROTHIAZOLE-5-CARBALDEHYDE 4-CHLORO-2-(1-METHYLIMIDAZOLYL-2-THIO)-5-THIAZOLECARBOXALDEHYDE 4-CHLORO-2-(2-BENZOXAZOLYLTHIO)-5-THIAZOLECARBOXALDEHYDE 4-CHLORO-2-(4-MORPHOLINO)-5-THIAZOLECARBOXALDEHYDE 4-CHLORO-2-(4-CARBOMETHOXYL-1-PIPERIDINYL)-5-THIAZOLECARBOXALDEHYDE
4-CHLORO-2-[(4-METHYLPHENYL)AMINO]-1,3-THIAZOLE-5-CARBALDEHYDE 4-CHLORO-2-(1-PIPERIDIN-4-OL)-5-THIAZOLECARBOXALDEHYDE 4-CHLORO-2-(1-PYRROLIDINO)-5-THIAZOLECARBOXALDEHYDE 4-CHLORO-2-[(N-METHYL-N'-3-PHENYLPROPYL)AMINO]-5-THIAZOLECARBOXALDEHYDE 4-CHLORO-2-(4-METHYLPYRIMIDINYL-2-THIO)-5-THIAZOLECARBOXALDEHYDE
4-CHLORO-2-(1-PIPERIDINO)-5-THIAZOLECARBOXALDEHYDE 4-CHLORO-2-(4-OXO-PIPERIDINYL)-5-THIAZOLECARBOXALDEHYDE 4-CHLORO-2-(TERT-BUTYLAMINO)-5-THIAZOLECARBOXALDEHYDE

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4-Chlorothiazole-5-carboxaldehyde 5-Thiazolecarboxaldehyde, 4-chloro- (9CI) 4-chloro-1,3-thiazole-5-carbaldehyde 4-chloro-5-thiazolecarboxaldehyde 5-Thiazolecarboxaldehyde, 4-chloro- 4-Chlorothiazole-5-carboxaldehyde?New 4-Chlorothiazole-5-carbaldehyde 104146-17-0 ALDEHYDE