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D-erythro-Sphingosine, D9

CAS No.
2377379-55-8
Chemical Name:
D-erythro-Sphingosine, D9
Synonyms
D-erythro-Sphingosine, D9
CBNumber:
CB910326069
Molecular Formula:
C18H28D9NO2
Molecular Weight:
308.55
MDL Number:
MOL File:
2377379-55-8.mol
MSDS File:
SDS
Last updated:2025-07-27 11:21:25

D-erythro-Sphingosine, D9 Properties

Boiling point 445.922±45.00 °C(Press: 760.00 Torr)(predicted)
Density 0.940±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility Chloroform: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid

D-erythro-Sphingosine, D9 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24371 Sphingosine-d9 (d18:1) ≥99%deuteratedforms(d1-d9) 2377379-55-8 1mg $516 2026-04-30 Buy
Cayman Chemical 24371 Sphingosine-d9 (d18:1) ≥99% deuterated forms (d1-d9) 2377379-55-8 1 mg $469 2024-03-01 Buy
ChemScene CS-0627116 Sphingosine-d9 d18:1 2377379-55-8 1mg $1116 2026-06-04 Buy
aablocks AA01X6CB Sphingosine-d9 (d18:1) ≥99%deuteratedforms(d1-d9) 2377379-55-8 1mg $516 2026-06-01 Buy
Product number Packaging Price Buy
24371 1mg $516 Buy
24371 1 mg $469 Buy
CS-0627116 1mg $1116 Buy
AA01X6CB 1mg $516 Buy

D-erythro-Sphingosine, D9 Chemical Properties, Uses, Production

Description

Sphingosine-d9 is intended for use as an internal standard for the quantification of sphingosine by GC- or LC-MS. Sphingosine is formed primarily from the breakdown of ceramide.1 Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.1 Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.2,3,4

Uses

Sphingosine-d9 (d18:1) (D-eytho-Sphigosie C18-d9) is deuterium labeled Sphingosine (d18:1)[1].

References

1. Hannun, Y.A., Luberto, C., and Argraves, K.M. Enzymes of sphingolipid metabolism: From modular to integrative signaling Biochemistry 40(16),4893-4903(2001).
2. Takuwa, Y., Takuwa, N., and Sugimoto, N. The Edg family G protein-coupled receptors for lysophospholipids: Their signaling properties and biological activities J. Biochem. 131(6),767-771(2002).
3. Ishii, I., Fukushima, N., Ye, X., et al. Lysophospholipid receptors: Signaling and biology Annu. Rev. Biochem. 73,321-354(2004).
4. Kluk, M.J., and Hla, T. Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors Biochim. Biophys. Acta 1582(1-3),72-80(2002).

D-erythro-Sphingosine, D9 Preparation Products And Raw materials

Raw materials

Preparation Products

D-erythro-Sphingosine, D9 Suppliers

Global Suppliers ( 6)
Supplier Tel Email Country ProdList Advantage
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1978 58
CHINA ISOTOPE CO., LIMITED 02151600108 13062666369 info@isotopechem.com China 4721 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
D-erythro-Sphingosine, D9 2377379-55-8