MMP-13 substrate, fluorogenic
- CAS No.
- Chemical Name:
- MMP-13 substrate, fluorogenic
- Synonyms
- 390 MMP FRET SUBSTRATE IV;MMP-13 substrate, fluorogenic;MCA-P-CHA-G-NVA-HA-DAP(DNP)-NH2;MCA-PRO-CHA-GLY-NVA-HIS-ALA-DPA-NH2;COLLAGENASE-3 SUBSTRATE, FLUOROGENIC;MCA-PRO-CHA-GLY-NVA-HIS-ALA-DAP(DNP)-NH2
- CBNumber:
- CB9106110
- Molecular Formula:
- C51H65N13O15
- Molecular Weight:
- 1100.14
- MDL Number:
- MFCD02179378
- MOL File:
- Mol file
MMP-13 substrate, fluorogenic price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 444235-M | MMP-13 Substrate, Fluorogenic A quenched fluorescence substrate for MMP-13 (collagenase-3; kcat/Km = 1.09 x 10⁶ M⁻¹s⁻¹). | 1 mg | $291 | 2026-04-30 | Buy | |
| Sigma-Aldrich | 444235-M | MMP-13 Substrate, Fluorogenic A quenched fluorescence substrate for MMP-13 (collagenase-3; kcat/Km = 1.09 x 10⁶ M⁻¹s⁻¹). | 1 unit | $271 | 2025-07-31 | Buy |
MMP-13 substrate, fluorogenic Chemical Properties, Uses, Production
Description
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. 7-methoxycoumarin-4-acetyl (Mca) is released by cleavage of Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2, of which the fluorescence can be used to quantify MMP-1, MMP-3 and MMP-26 activity.
Uses
Matrix metalloproteinases (MMP) are a family of zinc-dependent endopeptidases th at degrade matrix proteins. MMPs include collagenases, gelatinases, matrilysins, enamelysins, metalloelastases, stromelysins and other structural protein and receptor lysins. The activity of these enzymes is selectively inhibited or measured by appropriately labeled peptides. MCA-Pro-Cha-Gly-Nva-His-Ala-DNP-DPA-NH2 is used as a fluorogenic substrate for matrix metalloprotein-13 (collagenase-3, MMP-13).
Biological Activity
Primary Target
A quenched fluorescence substrate for MMP-13 (collagenase-3)', 'kcat/Km = 1.09 x 106 M-¹ sec-¹ for MMP-13 (collagenase-3)
Sequene
Mca-Pro-Cha-Gly-Nva-His-Ala-Dap(Dnp)-NH2
MMP-13 substrate, fluorogenic Preparation Products And Raw materials
Raw materials
Preparation Products
MMP-13 substrate, fluorogenic Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7446 | 58 |
| Phygene | 18059081430 | 2070812664@qq.com | China | 1232 | 58 |
