halenaquinone
- CAS No.
- 86690-14-4
- Chemical Name:
- halenaquinone
- Synonyms
- halenaquinone;(S)-12bβ-Methyl-1H-5-oxabenzo[k]acephenanthrylene-3,6,8,11(2H,12bH)-tetrone;1H-Benzo[6,7]phenanthro[10,1-bc]furan-3,6,8,11(2H,12bH)-tetrone, 12b-methyl-, (12bS)-
- CBNumber:
- CB91334875
- Molecular Formula:
- C20H12O5
- Molecular Weight:
- 332.31
- MDL Number:
- MOL File:
- 86690-14-4.mol
| Boiling point | 601.2±55.0 °C(Predicted) |
|---|---|
| Density | 1.501±0.06 g/cm3(Predicted) |
| FDA UNII | X57WT4EJ87 |
halenaquinone Chemical Properties, Uses, Production
Uses
Halenaquinone is a phosphatidylinositol 3-kinase inhibitor and can be isolated from the marine sponge Petrosia alfiani. Halenaquinone inhibits RANKL-induced osteoclastogenesis, and induces cell apoptosis in PC12 cells[1][2][3].
References
[1] Deborah M. Roll, et al. Halenaquinone, a pentacyclic polyketide from a marine sponge. ：Journal of the American Chemical Society.Vol 105/Issue 19.
[2] Tsukamoto S, et al. Halenaquinone inhibits RANKL-induced osteoclastogenesis. Bioorg Med Chem Lett. 2014;24(22):5315-5317. DOI:10.1016/j.bmcl.2014.09.043
[3] Fujiwara H, et al. Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells. Eur J Pharmacol. 2001;413(1):37-45. DOI:10.1016/s0014-2999(00)00944-4
halenaquinone Preparation Products And Raw materials
Raw materials
Preparation Products
halenaquinone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
