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Levocetirizine dihydrochloride

Levocetirizine dihydrochloride structure

CAS No.: 130018-87-0

Chemical Name:: Levocetirizine dihydrochloride

Synonyms: LEVOCETIRIZINE 2HCL;LEVOCETIRIZINE HCL;LEVOCETRIZINE DIHYDROCHLORIDE;(R)-Cetirizine diHCl (Levocetirizine diHCl);[2-[4-[(r)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride;DDDB;LevocetrizineHCl;Levocetirizine HCI;Levocitirizine 2HCL;LEVOCETIRIZINE DIHCL

CBNumber:: CB9135031

Molecular Formula:: C21H27Cl3N2O3

Molecular Weight:: 461.81

MDL Number:: MFCD07366507

MOL File:: 130018-87-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-18 07:23:31

Product description	Number	Pack Size	Price
Levocetirizine dihydrochloride ≥98% (HPLC)	L7795	10mg	$107
Levocetirizine dihydrochloride ≥98% (HPLC)	L7795	50mg	$415
Levocetirizine dihydrochloride United States Pharmacopeia (USP) Reference Standard	1359969	200mg	$440
Levocetirizine Dihydrochloride >98.0%(HPLC)(T)	L0264	1g	$91
Levocetirizine Dihydrochloride >98.0%(HPLC)(T)	L0264	5g	$274
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Levocetirizine dihydrochloride Properties

Melting point	215-220°C
alpha	D25 -12.79° (c = 1 in water)
storage temp.	room temp
solubility	H2O: ≥23mg/mL
form	powder
color	White to Almost white
Water Solubility	H2O: ≥23mg/mL
Merck	14,2022
Stability	Hygroscopic
InChI	InChI=1/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H/t21-;;/s3
InChIKey	PGLIUCLTXOYQMV-MGIYCFTINA-N
SMILES	C(O)(=O)COCCN1CCN([C@@H](C2=CC=C(Cl)C=C2)C2=CC=CC=C2)CC1.[H]Cl.[H]Cl \|&1:11,r\|
CAS DataBase Reference	130018-87-0(CAS DataBase Reference)
FDA UNII	SOD6A38AGA
NCI Drug Dictionary	levocetirizine dihydrochloride
UNSPSC Code	41116107
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H302-H400

Precautionary statements

Hazard Codes

Risk Statements

Safety Statements

RIDADR

UN 3077 9 / PGIII

WGK Germany

RTECS

AG0990000

HS Code

29335990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Aquatic Acute 1

NFPA 704

	0
2		0

Levocetirizine dihydrochloride price More Price(85)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	L7795	Levocetirizine dihydrochloride ≥98% (HPLC)	130018-87-0	10mg	$107	2026-04-30	Buy
Sigma-Aldrich	L7795	Levocetirizine dihydrochloride ≥98% (HPLC)	130018-87-0	50mg	$415	2026-04-30	Buy
Sigma-Aldrich	1359969	Levocetirizine dihydrochloride United States Pharmacopeia (USP) Reference Standard	130018-87-0	200mg	$440	2026-04-30	Buy
TCI Chemical	L0264	Levocetirizine Dihydrochloride >98.0%(HPLC)(T)	130018-87-0	1g	$91	2026-04-30	Buy
TCI Chemical	L0264	Levocetirizine Dihydrochloride >98.0%(HPLC)(T)	130018-87-0	5g	$274	2026-04-30	Buy

Product number	Packaging	Price	Buy
L7795	10mg	$107	Buy
L7795	50mg	$415	Buy
1359969	200mg	$440	Buy
L0264	1g	$91	Buy
L0264	5g	$274	Buy

Levocetirizine dihydrochloride Chemical Properties,Uses,Production

Uses

Anti Histaminic

Uses

Levocetirizine dihydrochloride has been used as standard in the thin layer chromatography optimization and in preparation of racemic cetirizine standard for subcritical fluid chromatography-tandem mass spectrometry analysis.

General Description

Levocetirizine dihydrochloride,(R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy] acetic acid dihydrochloride, (Xyzal) is awhite, crystalline powder and is water soluble. ThisR-enantiomer is has a 30-fold higher affinity than the S-enantiomer,and dissociates more slowly from H₁-receptors.Pharmacologically, it displays the same receptor and CNSselecitivity profile as the racemate, cetirizine,and thus the same therapeutic advantages. Levocetirizine isindicated for the relief of symptoms associated with allergicrhinitis (seasonal and perennial) in adults and children 6 yearsof age and older and for the treatment of the uncomplicatedskin manifestations of chronic idiopathic urticaria in adultsand children 6 years of age and older. Its pharmacokineticsand clearance profile are essentially the same as the racemate,cetirizine .

Biochem/physiol Actions

Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.

Levocetirizine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Levocetirizine dihydrochloride Suppliers

Global( 587)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+86-17531190177	faithe@yan-xi.com	China	5838	58
RongNa Biotechnology Co.,Ltd	+86-86-13583358881 +8618560316533	Brad@rongnabiotech.com	China	3371	58
Wuhan Fortuna Chemical Co., Ltd	+86-27-59207850	info@fortunachem.com	China	5998	58
Changzhou Rokechem Technology Co., Ltd.	18758118018	sales001@rokechem.com	China	254	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2451	58
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	13343047651	admin@zlchemi.com	China	3689	58
Wuhan JiyunZen Tech Co., Ltd.	+86-18062099985	Amyjiyunzen@yeah.net	China	672	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
RongNa Biotechnology Co.,Ltd	58
Wuhan Fortuna Chemical Co., Ltd	58
Changzhou Rokechem Technology Co., Ltd.	58
Henan Bao Enluo International TradeCo.，LTD	58
airuikechemical co., ltd.	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Wuhan JiyunZen Tech Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from Levocetirizine dihydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-14	Levocetirizine dihydrochloride 130018-87-0	$10.00	1ASSAYS	99%	1 ton	RongNa Biotechnology Co.,Ltd
2026-08-14	Levocetirizine dihydrochloride 130018-87-0		1kg	98.0%~102.0%; USP41	1500kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-07-18	Levocetirizine dihydrochloride 130018-87-0		1kg	98%	1000kgs	Shaanxi Dideu New Materials Co. Ltd

Levocetirizine dihydrochloride
130018-87-0
$10.00
99%
RongNa Biotechnology Co.,Ltd

Levocetirizine dihydrochloride
130018-87-0
98.0%~102.0%; USP41
WUHAN FORTUNA CHEMICAL CO., LTD

Levocetirizine dihydrochloride
130018-87-0
$0.00
98%
Shaanxi Dideu New Materials Co. Ltd

Levocetirizine dihydrochloride Spectrum

Levocetirizine dihydrochloride(130018-87-0)¹HNMR Levocetirizine dihydrochloride(130018-87-0)¹HNMR

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LEVOCETIRIZINE DIHCL LEVOCETIRIZINE DIHYDROCHLORIDE [2-[4-[(R)-(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINYL]ETHOXY]-ACETIC ACID 2HCL (R)-Cetirizine (hydrochloride) LevocetrizineHCl LEVOCITIRIZINE DIHYDROCHLORIDE (R) -2-[2-[4-[(4-Chlorophenyl) phenylmethyl] piperazin-1-yl]ethoxy]acetic acid dihydrochloride (2-(4-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl)ethoxy)acetic acid dihydrochloride Levocitirizine 2HCL Levocetirizine dihydrochloride [2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride 2-[2-[4-[(R)-(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride DDDB Cetirizine hydrochloride sinistral (R)-Form dihydrochloride LEVOCETIRIZINE;(R)-CETIRIZINE (HYDROCHLORIDE) LevocetirizineDihydrochloride> Levocetirizine Dihydrochlorid Levocetirizine dihydrochloride USP/EP/BP Levocetirizine Hydrochloride Impurities Levocetirizine Dihydrochloride Powder Levocetirizine D4 DihydrochlorideQ: What is Levocetirizine D4 Dihydrochloride Q: What is the CAS Number of Levocetirizine D4 Dihydrochloride Q: What is the storage condition of Levocetirizine D4 Dihydrochloride Levocetirizine DihydrochlorideQ: What is Levocetirizine Dihydrochloride Q: What is the CAS Number of Levocetirizine Dihydrochloride Q: What is the storage condition of Levocetirizine Dihydrochloride Levocetirizine Dihydrochloride (1359969) (-)-Cetirizine Dihydrochloride Xyzal Dihydrochloride (R)-Cetirizine DiHCl Levocetirizine HCI LEVOCETIRIZINE HYDROCHLORIDE IP Levocetirizine Dihydrochloride, ≥ 98.0% Levocetirizine Dihydrochloride -IHS/IPS Levocetirizine dihydrochloride IMpurity Levocetirizine Dihydrochloride, 10 mM in DMSO (R)-Cetirizine diHCl (Levocetirizine diHCl) [2-[4-[(r)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride LEVOCETIRIZINE 2HCL LEVOCETIRIZINE HCL LEVOCETRIZINE DIHYDROCHLORIDE 130018-87-0 3008-87-0 C21H25ClN2O32ClH Antibiotics Levocitirizine 2HCl API Histamine receptor API's Levocetirizine