ChemicalBook >> CAS DataBase List >>L96.TEA
L96.TEA
- CAS No.
- 1159408-62-4
- Chemical Name:
- L96.TEA
- Synonyms
- L96.TEA;GalnAc-L96 TEA;GalNac-L96-Succinate, TEA salt;Triethylamine 4-[[(3R,5S)-1-[1-[[(2R,3R,4R,5R,6R)-3-Acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]-16,16-bis[[3-[[3-[5-[[(2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]pentanamido]propyl]amino]-3-oxopropoxy]methyl]-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oyl]-5-[[bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-pyrrolidinyl]ox;Butanedioic acid, 1-[(3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] ester, compd. with N,N-diethylethanamine (1:1);Triethylamine 4-(((3R,5S)-1-(1-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-16,16-bis((3-((3-(5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanamido)propyl)amino)-3-oxopropoxy)methyl)-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oyl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)pyrrolidin-3-yl)oxy)-4-oxobutanoate;Triethylamine 4-[[(3R,5S)-1-[1-[[(2R,3R,4R,5R,6R)-3-Acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]-16,16-bis[[3-[[3-[5-[[(2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]pentanamido]propyl]amino]-3-oxopropoxy]methyl]-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oyl]-5-[[bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-pyrrolidinyl]oxy]-4-oxobutanoate
- CBNumber:
- CB913592979
- Molecular Formula:
- C121H179N11O45.C6H15N
- Molecular Weight:
- 2608.96
- MDL Number:
- MOL File:
- 1159408-62-4.mol
Last updated:2025-08-21 14:05:29
L96.TEA Chemical Properties,Uses,Production
Uses
GalNAc-L96, a triantennary N-acetylgalactosamine (GalNAc), is a ligand of asialoglycoprotein receptor (ASGPR). GalNAc-L96 can be used to synthesize GalNAc-siRNA and can be used for oligonucleotide delivery[1].
References
[1] Anna Clua, et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules. 2022 Jun 20;27(12):3944. DOI:10.3390/molecules27123944
[2] JAYAPRAKASH K. NAIR. Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing[J]. Journal of the American Chemical Society, 2014, 136 49: 16958-16961. DOI: 10.1021/ja505986a
L96.TEA Preparation Products And Raw materials
Raw materials
Preparation Products
L96.TEA Suppliers
Global( 25)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Shenzhen Nexcon Pharmatechs Ltd. | +86-0755-89396905 +86-18025329037 | admin@nexconn.com | China | 3119 | 58 |
| Suzhou Biosyntech Co., Ltd | +86-13921151340 | sales2@biosyntech-suzhou.com | China | 104 | 58 |
| Shenzhen HwaGen Pharmaceutical Co.,Ltd | 18927339850 | xiaodong.shi@rafflespt.com | China | 277 | 58 |
| Wuhu Huaren Science and Technology Co., Ltd. | 0553-0553-5842013-801 18155347026 | jinhuaren@huarensh.com | China | 743 | 58 |
| Shenzhen Yuzhong Pharmaceutical Technology Co., Ltd. | 13414494621 | chenchao02lzu@126.com | China | 130 | 58 |
| Shochem(Shanghai)Co.,Ltd | +86-021-51783479 +86-13816874662 | info@shochem.com | China | 307 | 58 |
| Wuhan Ruilida Biomedical Technology Co., Ltd. | 18201884268 | magean83@163.com | China | 1809 | 58 |
| Suzhou Biosyntech Co., Ltd. | +86-0512-63001269 +86-13921151340 | sales@biosyntech-suzhou.com | China | 104 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62320 | 58 |
L96.TEA
Triethylamine 4-[[(3R,5S)-1-[1-[[(2R,3R,4R,5R,6R)-3-Acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]-16,16-bis[[3-[[3-[5-[[(2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]pentanamido]propyl]amino]-3-oxopropoxy]methyl]-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oyl]-5-[[bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-pyrrolidinyl]oxy]-4-oxobutanoate
GalnAc-L96 TEA
Triethylamine 4-[[(3R,5S)-1-[1-[[(2R,3R,4R,5R,6R)-3-Acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]-16,16-bis[[3-[[3-[5-[[(2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl]oxy]pentanamido]propyl]amino]-3-oxopropoxy]methyl]-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oyl]-5-[[bis(4-methoxyphenyl)(phenyl)methoxy]methyl]-3-pyrrolidinyl]ox
GalNac-L96-Succinate, TEA salt
Triethylamine 4-(((3R,5S)-1-(1-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-16,16-bis((3-((3-(5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanamido)propyl)amino)-3-oxopropoxy)methyl)-5,11,18-trioxo-14-oxa-6,10,17-triazanonacosan-29-oyl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)pyrrolidin-3-yl)oxy)-4-oxobutanoate
Butanedioic acid, 1-[(3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] ester, compd. with N,N-diethylethanamine (1:1)
1159408-62-4
GalNAc
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