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Lepadin H

Lepadin H Structure
Lepadin H structure
CAS No.
412328-25-7
Chemical Name:
Lepadin H
Synonyms
Lepadin H;2,4-Octadienoic acid, (2S,3R,4aS,5S,8aR)-decahydro-5-[(5R)-5-hydroxyoctyl]-2-methyl-3-quinolinyl ester, (2E,4E)-
CBNumber:
CB914133795
Molecular Formula:
C26H45NO3
Molecular Weight:
419.64
MDL Number:
MOL File:
412328-25-7.mol
Last updated:2025-08-21 22:16:43
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Lepadin H Properties

Boiling point 528.415±25.00 °C(Press: 760.00 Torr)(predicted)
Density 1.011±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 15.258±0.20(predicted)

Lepadin H Chemical Properties,Uses,Production

Uses

Lepadin H is a marine alkaloid and ferroptosis inducer. Lepadin H exhibits significant cytotoxicity, promotes p53 expression, increases ROS production and lipid peroxidation, decreases SLC7A11 and GPX4 levels, and upregulates ACSL4 expression. Lepadin H induces ferroptosis through the p53-SLC7A11-GPX4 pathway[1].

References

[1] Wang W, et al. Marine Alkaloid Lepadins E and H Induce Ferroptosis for Cancer Chemotherapy. J Med Chem. 2023 Aug 24;66(16):11201-11215. DOI:10.1021/acs.jmedchem.3c00659

Lepadin H Preparation Products And Raw materials

Raw materials

Preparation Products

Lepadin H Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19962 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5925 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29579 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Nantong QuanYi Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58

View Lastest Price from Lepadin H manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lepadin H pictures 2025-08-21 Lepadin H
412328-25-7
 US $3400.00-2580.00 / mg 10g TargetMol Chemicals Inc.
  • Lepadin H pictures
  • Lepadin H
    412328-25-7
  • US $3400.00-2580.00 / mg
  • TargetMol Chemicals Inc.
Lepadin H 2,4-Octadienoic acid, (2S,3R,4aS,5S,8aR)-decahydro-5-[(5R)-5-hydroxyoctyl]-2-methyl-3-quinolinyl ester, (2E,4E)- 412328-25-7