Pyridine, 5-bromo-2-ethyl-
- CAS No.
- 38749-90-5
- Chemical Name:
- Pyridine, 5-bromo-2-ethyl-
- Synonyms
- 5-Bromo-2-ethylpyridine;5-BroMo-2-ethylpyridin;5-BroMo-2-ethylpyidine;Pyridine, 5-bromo-2-ethyl-;Pyridine, 5-bromo-2-ethyl- (9CI);2-methylthiazole-37-carboxylic acid;Pyridine, 5-bromo-2-ethyl- ISO 9001：2015 REACH
- CBNumber:
- CB91454946
- Molecular Formula:
- C7H8BrN
- Molecular Weight:
- 186.05
- MDL Number:
- MFCD11226235
- MOL File:
- 38749-90-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933399990 |
Pyridine, 5-bromo-2-ethyl- price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR315121 | 5-Bromo-2-ethylpyridine 98% | 38749-90-5 | 1g | $66 | 2026-06-04 | Buy |
| Apolloscientific | OR315121 | 5-Bromo-2-ethylpyridine 98% | 38749-90-5 | 5g | $270 | 2026-06-04 | Buy |
| Apolloscientific | OR315121 | 5-Bromo-2-ethylpyridine 98% | 38749-90-5 | 25g | $1333 | 2026-06-04 | Buy |
| Apolloscientific | OR315121 | 5-Bromo-2-ethylpyridine 98% | 38749-90-5 | 100g | $4438 | 2026-06-04 | Buy |
| Activate Scientific | AS32362 | 5-Bromo-2-ethylpyridine 98% | 38749-90-5 | 1g | $73 | 2026-06-04 | Buy |
Pyridine, 5-bromo-2-ethyl- Chemical Properties, Uses, Production
Synthesis
624-28-2
557-20-0
38749-90-5
General procedure for the synthesis of 2-ethyl-5-bromopyridine from 2,5-dibromopyridine and diethylzinc: A suspension of 2,5-dibromopyridine (10 g, 42.21 mmol) and tetrakis(triphenylphosphine)palladium (Pd(PPh3)4, 2.43 g, 2.11 mmol) in tetrahydrofuran (THF, 100 mL) was slowly added to a suspension of 1 M diethyl Zinc (Et2Zn, 42.2 mL, 42.21 mmol). The reaction mixture was stirred at 0 °C for 30 min, then warmed up to room temperature and continued stirring for 1 h. The reaction was completed with saturated carbon dioxide. Upon completion of the reaction, the reaction was quenched with saturated sodium bicarbonate (NaHCO3) solution and extracted with ethyl acetate (EtOAc). The combined organic layers were washed sequentially with water and saturated saline, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with 4% ethyl acetate/petroleum ether as eluent to afford 5-bromo-2-ethylpyridine as a light yellow liquid (3 g, 38% yield). Thin layer chromatography (TLC) Rf value was 0.6 (10% ethyl acetate/petroleum ether).1H NMR (400MHz, CDCl3): δ 8.57 (d, J=2.4Hz, 1H), 7.72-7.69 (m, 1H), 7.06 (d, J=8.0Hz, 1H), 2.81-2.75 (m, 2H), 1.29 (t, J= 8.0 Hz, 3H).
References
[1] Patent: WO2015/36759, 2015, A1. Location in patent: Page/Page column 198
[2] Patent: US2014/275182, 2014, A1. Location in patent: Paragraph 0374; 0375
[3] Patent: US8912227, 2014, B1. Location in patent: Page/Page column 74
[4] Patent: WO2015/134038, 2015, A1. Location in patent: Page/Page column 90
Pyridine, 5-bromo-2-ethyl- Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 999 | 60 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
View Latest Price from Pyridine, 5-bromo-2-ethyl- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Pyridine, 5-bromo-2-ethyl-
38749-90-5
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-01-01 | Pyridine, 5-bromo-2-ethyl-
38749-90-5
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- Pyridine, 5-bromo-2-ethyl-
38749-90-5
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Pyridine, 5-bromo-2-ethyl-
38749-90-5
- $1.00
- 99%
- Career Henan Chemical Co
