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Methyl 4-chlorosalicylate

Methyl 4-chlorosalicylate structure

CAS No.: 22717-55-1

Chemical Name:: Methyl 4-chlorosalicylate

Synonyms: Nsc300575;Methyl 4-chlorosalicylate;Methyl 4-chloro-2-hydroxybenzoate;4-Chloro-2-hydroxy-benzoic acid Methyl ester;Benzoic acid, 4-chloro-2-hydroxy-, Methyl ester;JR-13528, Methyl 4-chloro-2-hydroxybenzoate, 97%

CBNumber:: CB91457619

Molecular Formula:: C8H7ClO3

Molecular Weight:: 186.59

MDL Number:: MFCD03407436

MOL File:: 22717-55-1.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:46

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Methyl 4-chlorosalicylate Properties

Boiling point	127 °C(Press: 15 Torr)
Density	1.354±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	8.79±0.10(Predicted)
form	solid
color	tan

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338
Hazard Codes	Xi
HS Code	2916399090

Methyl 4-chlorosalicylate price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	M340405	Methyl4-Chloro-2-hydroxybenzoate	22717-55-1	100mg	$60	2021-12-16	Buy
AK Scientific	J50165	Methyl4-chloro-2-hydroxybenzoate	22717-55-1	100g	$450	2021-12-16	Buy
Apolloscientific	OR59351	Methyl4-chloro-2-hydroxybenzoate	22717-55-1	25g	$631	2021-12-16	Buy
SynQuest Laboratories	2629-5-15	Methyl 4-chloro-2-hydroxybenzoate	22717-55-1	25g	$696	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0014215	METHYL 4-CHLORO-2-HYDROXYBENZOATE 95.00%	22717-55-1	1G	$765.23	2021-12-16	Buy

Product number	Packaging	Price	Buy
M340405	100mg	$60	Buy
J50165	100g	$450	Buy
OR59351	25g	$631	Buy
2629-5-15	25g	$696	Buy
HCH0014215	1G	$765.23	Buy

Methyl 4-chlorosalicylate Chemical Properties,Uses,Production

Synthesis

5106-98-9

22717-55-1

1. Synthesis of methyl 4-chloro-2-hydroxybenzoate (2f): 4-chloro-2-hydroxybenzoic acid (200 g, 1.16 mol) was mixed with 40 ml of concentrated hydrochloric acid and added to 400 ml of methanol, followed by addition of sulfuric acid. The reaction mixture was heated to reflux for 20 hours. After completion of the reaction, the solvent was removed by evaporation under reduced pressure. The residue was poured into saturated aqueous Na2CO3 solution and extracted with ether (3 x 500 ml). The organic layers were combined, dried with anhydrous Na2SO4 and the solvent was evaporated to give the crude product 2f (191.6 g, 88.6% yield) as an oil. The product was used for subsequent reactions without further purification.IR (pure) showed absorption peaks: 3150 (OH), 1728 (C=O) and 1678 (C=O) cm-1.1H NMR (CDCl3) δ: 10.27 (br s, 1H, OH), 7.47 (d, 1H, J=8Hz, Ar-H), 6.80 (d, 1H, J=2Hz, Ar-H). 2Hz, Ar-H), 6.63 (d, 1H, Ar-H), 3.85 (s, 3H, OCH3).

References

[1] Patent: US4888353, 1989, A
[2] Patent: EP234872, 1991, B1
[3] Patent: US6313310, 2001, B1
[4] Patent: US5484763, 1996, A
[5] Patent: US4420476, 1983, A

Methyl 4-chlorosalicylate Preparation Products And Raw materials

Raw materials

4-Chlorosalicylic acid Methanol Iodomethane Sulfuric acid

Preparation Products

Methyl 2,4-dihydroxybenzoate 6-CHLOROBENZO[D]ISOXAZOL-3-OL Benzoicacid,2-(carboxymethoxy)-4-chloro-

Methyl 4-chlorosalicylate Suppliers

Global( 83)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2161	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
RR Scientific LLC	+86-13917743231	sales@rrscientific.com	United States	878	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24727	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19183	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33338	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

Supplier	Advantage
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
RR Scientific LLC	58
HANGZHOU LEAP CHEM CO., LTD.	58
Aromsyn Co., Ltd.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58

View Lastest Price from Methyl 4-chlorosalicylate manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-01-15	methyl4-chloro-2-hydroxybenzoate 22717-55-1	US $0.00 / KG	1KG	98.2%	100 tons	Honest Joy Holdings Limited
	2019-07-06	22717-55-1 22717-55-1	US $1.00 / KG	1KG	98%	200kg	Career Henan Chemical Co

methyl4-chloro-2-hydroxybenzoate
22717-55-1
US $0.00 / KG
98.2%
Honest Joy Holdings Limited

22717-55-1
22717-55-1
US $1.00 / KG
98%
Career Henan Chemical Co

Methyl 4-chlorosalicylate Spectrum

Methyl 4-chlorosalicylate(22717-55-1)¹HNMR

22717-55-1(Methyl 4-chlorosalicylate)Related Search:

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Nsc300575 4-Chloro-2-hydroxy-benzoic acid Methyl ester Benzoic acid, 4-chloro-2-hydroxy-, Methyl ester Methyl 4-chloro-2-hydroxybenzoate Methyl 4-chlorosalicylate JR-13528, Methyl 4-chloro-2-hydroxybenzoate, 97% 22717-55-1 blocks Carboxes